Development of minocycline as a neuroimmune therapy for alcohol use disorder

开发米诺环素作为酒精使用障碍的神经免疫疗法

• 批准号: 10378321
• 负责人: Daniel Roche
• 金额: $ 3.14万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-05 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10378321
• 关键词: Administrative Supplement; Birth; COVID-19 pandemic; Caregivers; Child; Childbirth; Development; Direct Costs; Grant; K-Series Research Career Programs; Manuscripts; Mentored Research Scientist Development Award; Mentors; Minocycline; Neuroimmune; Paternity Leave; Productivity; Research; Research Assistant; Research Project Grants; Role; Training; United States National Institutes of Health; Wife; alcohol use disorder; care providers; career development; experience; interest; research study; response

Project Summary/Abstract This supplement application is in response to the Notice of Special Interest (NOT-OD-20-054): Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars. The PI is in the fourth year of his K01 Mentored Research Scientist Development Award, and his wife gave birth to their first child on 05/18/2020. The PI and his wife have alternated being the sole care providers over the past 10+ months since childbirth. The PI was on official paternity leave until 12/14/20, and his role as sole caregiver until this return date significantly impeded his manuscript and grant productivity, K01 training experiences, and K01 research study progress; all difficulties were further compounded due to the COVID-19 pandemic. The PI is requesting 6 months of research assistant support ($29,092 in direct costs) to support the completion of his delayed K01 research project and to facilitate his return to full productivity post-childbirth.

项目摘要/摘要 此补充申请是响应特殊利益通知（NOT-OD-20-054）： 行政补充剂以促进研究连续性和NIH指导职业的保留 发展（K）奖获得者和学者。 PI在他的K01指导研究的第四年 科学家发展奖和他的妻子于2020年5月18日生下了第一个孩子。 PI和他的妻子 自分娩以来，过去10个月以来，已经成为唯一的护理提供者。 PI是正式的 父亲恋离开直到12/14/20，他作为唯一护理人员的角色直到这个回报日期极大地阻碍了他的 手稿和授予生产力，K01培训经验以及K01研究进度；所有困难 由于19号大流行，因此进一步复杂了。 PI要求6个月的研究助理 支持（直接费用为29,092美元），以支持完成其延迟K01研究项目的完成并促进 他恢复了孩子后的全部生产力。