Community-led Action Research in Oncology: Pandemic-appropriate Radiotherapy Innovations Evaluated for LMICs

社区主导的肿瘤学行动研究：针对中低收入国家评估适合流行病的放射治疗创新

• 批准号: 10380931
• 负责人: Steven D Leach
• 金额: $ 17.18万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2021-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10380931
• 关键词: 2019-nCoV; Action Research; Address; Back; COVID-19; COVID-19 pandemic; Cancer Center; Cancer Control; Caribbean region; Cities; Clinic; Clinical; Communities; Community Healthcare; Comprehensive Cancer Center; Consensus; Country; Data Collection; Development; Disease; Ensure; Evaluation; Future; Goals; Health; Healthcare; Honduras; Hygiene; Infection prevention; International; Knowledge; Latin America; Latin American; Maintenance; Malignant Neoplasms; Manuals; Medical Oncologist; Medical Oncology; Medical Societies; Mentors; Methods; Morbidity - disease rate; New Hampshire; Norris Cotton Cancer Center; Oncology; Participant; Patients; Phase; Physicians; Preparation; Procedures; Process; Quality of Care; Radiation Oncology; Radiation therapy; Reporting; Research; Research Technics; Resources; Risk; Route; Safety; Schedule; Scientist; Series; Source; Teleconferences; Testing; United States National Institutes of Health; Virus; base; cancer care; cancer therapy; care outcomes; community based participatory research; community center; cost; design; evidence base; experience; infection risk; innovation; insight; interest; low and middle-income countries; mortality; multidisciplinary; multimodality; operation; pandemic disease; public health emergency; research study; response; safety and feasibility; safety testing; ventilation

ABSTRACT Community-led Action Research in Oncology – Pandemic-appropriate Radiotherapy Innovations Evaluated for LMICs (CLARO PARTE for LMICs) This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA- 21-033. This participatory action research (PAR) study will assess radiotherapy (RT) innovations in partnership with oncology professionals in Latin America and the Caribbean (LAC). We will leverage global experience and relationships of the Community-led Action Research in Oncology (CLARO) global oncology research team at Norris Cotton Cancer Center (NCCC) and involve RT professionals throughout LAC in evaluating “frugal innovations,” which were developed during the COVID-19 pandemic and are defined as the creation of unexpected solution that are simpler and disruptive alternatives to provide adequate healthcare within reach of everyone (Tran et al. 2016). Our overall goal is to identify frugal innovations and evaluate them for safety, efficiency, quality, feasibility, acceptability, and potential potency, to assess adaptability for use in future pandemics, or other public health emergencies. Phase 1 involves convening LAC RT professionals in a Project ECHOTM (Extension for Community Healthcare Outcomes) tele-mentoring partnership to share frugal innovations devised by their clinics during the COVID-19 pandemic. The Latin-American and Caribbean Society for Medical Oncology (SLACOM) will facilitate a panel of RT professionals joining the teleconferences. In Phase 2, physicians and scientists experienced in radiation oncology and innovation will evaluate innovations for effects on virus control, maintenance of clinical operations, and continuance of quality care by a multidisciplinary team applying international standards. The innovations that meet standards will advance to Phase 3, returning to the panel of LAC RT professionals where participants will engage in a Delphi consensus- building process to assess feasibility, acceptability within their setting, and potential potency. Relying on highly participatory and iterative processes, which are the hallmarks of Participatory Action Research (PAR), we will move from data collection and reflection to action and improvement, leveraging relationships between NCCC’s CLARO and SLACOM. Ultimately, we will develop a manual of scalable frugal RT innovations suitable for LMICs in a pandemic. Innovations will be organized topically: routing, hygiene, ventilation, PPE, and scheduling, etc. and further organized in matrixes by high/low impact and high/low cost.

抽象的 社区主导的肿瘤学行动研究 - 适合大流行的放射治疗创新 评估LMIC（LMIC的Claro Parte） 该申请是为了响应特殊利益通知（NOSI）而提交 21-033。这项参与行动研究（PAR）研究将评估放疗（RT）创新 拉丁美洲和加勒比海（LAC）的肿瘤专业人士。我们将利用全球经验， 社区主导的肿瘤学行动研究（CLARO）全球肿瘤研究团队的关系 诺里斯棉花癌中心（NCCC），并涉及整个LAC的RT专业人员评估“节俭 创新，“是在19009年大流行期间开发的，被定义为创造 意外的解决方案是更简单，更破坏性的替代方案，可提供足够的医疗保健 每个人（Tran等，2016）。我们的总体目标是确定节俭的创新并为了安全性进行评估， 效率，质量，可行性，可接受性和潜在效力，以评估将来使用的适应性 大流行病或其他公共卫生紧急情况。第1阶段涉及在项目中召集LAC RT专业人员 Echotm（社区医疗保健结果的扩展）远程合作伙伴关系以分享节俭 在COVID-19-19大流行期间，其诊所设计的创新。拉丁美洲和加勒比海 医学肿瘤学协会（Slacom）将促进由RT专业人员组成的专业人士。 在第二阶段，医生和科学家在放射肿瘤学和创新方面经历了评估 创新对病毒控制的影响，维持临床操作以及通过 多学科团队采用国际标准。符合标准的创新将提高到 第三阶段，返回LAC RT专业人员小组，参与者将参与Delphi共识 - 构建过程以评估可行性，可接受性和潜在效力。高度依赖 参与性和迭代过程，这是参与式行动研究（PAR）的标志，我们将 从数据收集和反思转变为行动和改进，利用NCCC之间的关系 克拉洛和斯拉科姆。最终，我们将制定一本可扩展的节俭RT创新手册 大流行中的LMIC。创新将局部组织：路由，卫生，通风，PPE和 日程安排等，并通过高/低冲击和高成本以矩阵进行进一步组织。