Factors Associated with Insulin Reluctance in Individuals with Type 2 Diabetes

2 型糖尿病患者胰岛素抵抗的相关因素

基本信息

批准号：
7630520
负责人：
Soohyun Nam
金额：
$ 0.78万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-05-14 至 2009-08-13
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7630520
关键词：
Accounting Acute Address Adult Affect American Applications Grants Attitude Behavior Belief Caring Centers for Disease Control and Prevention (U.S.)Chronic Disease Clinical Cross-Sectional Studies Diabetes Mellitus Disease Dose Education Educational Intervention Educational workshop Ethnic group Exposure to Health Health Personnel Health Professional Healthcare Systems Individual Insulin Knowledge Linear Regressions Medical Modeling Non-Insulin-Dependent Diabetes Mellitus Participant Patient Care Patients Perception Personal Satisfaction Population Prevalence Psychosocial Factor Public Health Questionnaires Research Research Design Research Personnel Risk Self Efficacy Self Management Testing Time Training United States Work design diabetic patient glycemic control pre-doctoral predictive modeling prevent psychologic satisfaction statistics

项目摘要

DESCRIPTION (provided by applicant): The purpose of this training grant application (F31) is to provide predoctoral support that will allow this investigator to examine the factors associated with a reluctance to use insulin therapy in individuals with type 2 diabetes. Common misconceptions about the need for transitioning to insulin therapy may affect a patient's ability to agree to and participate in self-management of type 2 diabetes using the prescribed therapy. Current approaches to address reluctance to begin and/or increase insulin therapy are largely educational, using classes and workshops to change attitudes and behavior. Little research exists, however, to determine which factors influence patients' reluctance to use insulin therapy. Therefore, the overall purpose of this study is to identify the factors related to reluctance to initiate insulin therapy (Insulin Reluctance= IR) in individuals with type 2 diabetes. The specific aims are 1) to examine the actual predictors of IR and to describe the relationship among IR in individuals with type 2 diabetes and their sociodemographic, biomedical, and psychosocial factors; and 2) to develop predictive model of IR. To accomplish these aims, a descriptive, correlational, cross-sectional study design will be used. All participants (n=139) will be asked to complete a study questionnaire. Descriptive statistics, uhivariate and bivariate analyses and multiple linear regression will be performed. To describe the relationship among IR, sociodemographic factors, biomedical factors, and psychosocial factors, Pearson correlation coefficients will be computed. To develop a predictive model of IR, multiple linear regression will be conducted. First the overall R-square of the complete model will be examined for significance. If the overall model is significant, the unique contribution of each separate variable in explaining the variance of IR will be tested. Given the significant burden of diabetes, public health care systems are seeking increasingly effective means of providing diabetes care. The proposed study will contribute to knowledge about IR, specifically about more appropriate clinical approaches for health professionals to use in working with type 2 diabetes patients. Thus, health care providers can make the transition to insulin therapy easier and facilitate timely introduction of insulin therapy to achieve optimal glycemic control. Furthermore, study findings may guide more effective educational interventions to reduce psychological barriers to insulin treatment.

描述（由申请人提供）：本培训补助金申请 (F31) 的目的是提供博士前支持，使研究者能够检查与 2 型糖尿病患者不愿使用胰岛素治疗相关的因素。关于转向胰岛素治疗的必要性的常见误解可能会影响患者同意并参与使用处方疗法自我管理 2 型糖尿病的能力。目前解决不愿意开始和/或增加胰岛素治疗的方法主要是教育性的，利用课程和研讨会来改变态度和行为。然而，很少有研究来确定哪些因素会影响患者不愿意使用胰岛素治疗。因此，本研究的总体目的是确定 2 型糖尿病患者不愿开始胰岛素治疗（胰岛素抵抗 = IR）的相关因素。具体目标是 1) 检查 IR 的实际预测因素，并描述 2 型糖尿病患者的 IR 与其社会人口统计学、生物医学和心理社会因素之间的关系； 2) 开发 IR 预测模型。为了实现这些目标，将使用描述性、相关性、横断面研究设计。所有参与者 (n=139) 将被要求填写一份研究问卷。将进行描述性统计、单变量和双变量分析以及多元线性回归。为了描述 IR、社会人口因素、生物医学因素和心理社会因素之间的关系，将计算皮尔逊相关系数。为了开发 IR 的预测模型，将进行多元线性回归。首先，将检查完整模型的整体 R 方的显着性。如果整体模型显着，则将检验每个单独变量在解释 IR 方差方面的独特贡献。鉴于糖尿病的巨大负担，公共卫生保健系统正在寻求越来越有效的方法来提供糖尿病护理。拟议的研究将有助于增进对 IR 的了解，特别是了解卫生专业人员在治疗 2 型糖尿病患者时使用的更合适的临床方法。因此，医疗保健提供者可以使向胰岛素治疗的过渡变得更容易，并促进及时引入胰岛素治疗以实现最佳血糖控制。此外，研究结果可能指导更有效的教育干预措施，以减少胰岛素治疗的心理障碍。