Mindfulness training with HIV-positive youth and adult family members to improve treatment adherence

对艾滋病毒呈阳性的青少年和成年家庭成员进行正念训练，以提高治疗依从性

基本信息

批准号：
9480702
负责人：
Julie Anne Denison
金额：
$ 12.83万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-05-01 至 2021-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9480702
关键词：
Accounting Address Adherence Adolescent Adolescent Behavior Adult Advisory Committees African American Age Alcohol or Other Drugs use Asthma Award Awareness Baltimore Behavior Behavioral Caring Characteristics Chronic Disease Chronically Ill Cities Clinic Cognitive Committee Members Conduct Disorder Conflict (Psychology)Counseling Data Data Analyses Development Diabetes Mellitus Disease Economically Deprived Population Educational Intervention Environment Family Family Caregiver Family Characteristics Family member Friends Funding Future Gender Generations Goals Group Meetings HIV HIV Infections HIV Seropositivity Health Home environment Individual Intervention Intervention Studies Intervention Trial Interview K-Series Research Career Programs Knowledge Logistics Maryland Medical Mental Health Mentored Research Scientist Development Award Mentors Methods Mind-Body Method Mindfulness Training Minority Morbidity - disease rate Outcome Parents Participant Pathway Analysis Peer Group Perinatal Pharmaceutical Preparations Pilot Projects Population Process Reading Research Research Methodology Research Personnel Research Training Risk Role Schools Scientist Self Management Social Environment Social Network Statistical Methods Structure Supervision Support System Surveys Testing Training United States United States National Institutes of Health Universities Viral Well in self Work Yoga Youth adolescent health age effect antiretroviral therapy base behavior change behavioral outcome body-mind career coping evidence base faculty mentor family support follow-up improved intergenerational medication compliance mindfulness mindfulness intervention mindfulness meditation mindfulness-based stress reduction mortality physical conditioning public health relevance response satisfaction senior faculty skills social statistics support network systems research theories therapy adherence treatment adherence urban underserved virology

项目摘要

DESCRIPTION (provided by applicant): The purpose of the proposed Mentored Research Scientist Career Development Award (K01) is to promote Dr. Denison's development as an independent scientist in mindfulness research with a focus on family-based mindful approaches to support HIV outcomes among adolescents living with HIV (ALHIV). ALHIV have low rates of medication adherence, increasing their risk for HIV-related morbidities and mortality. Current strategies to improve adherence, such as peer group meetings and adherence counseling, rely on educational and cognitive approaches often targeting individual behavior change without addressing the familial and social context where HIV management occurs. This career development award challenges this paradigm by examining if mindfulness offered to ALHIV and an adult family caregiver, that targets awareness of thought rather than changing the content of thought, supports the self-regulatory and medication adherence behaviors of ALHIV in Baltimore City, Maryland. The study's specific aims are to: (1) assess the family support networks among 191 participants in the parent R01. Data will characterize family support network composition and characteristics to inform family caregiver definitions and participant selection for Aims 2 and 3. (2) Examine the effects of MBSR on family support relationships and the logistics of a two-generation MBSR intervention, by conducting qualitative in-depth interviews with 20 ALHIV and 20 adult family members; and (3) examine the acceptability and feasibility of a pilot MBSR intervention among 25 ALHIV and adult family member pairs to improve adolescent adherence to ART through increased family support. The Johns Hopkins University is an ideal environment for this proposed training where the candidate will receive guidance throughout the award from Senior Faculty mentors and advisory committee members with expertise in mindfulness research and topics related to implementing mindfulness in this adolescent population, such as adolescent health, statistical methods and family-based interventions. Through a combination of directed readings, coursework, and supervised research opportunities, this mentoring team will support Dr. Denison in achieving her training goals to (1) gain expertise in mindfulness theory, interventions and research methods; (2) refine and test a two generation mindfulness-based stress reduction intervention; (3) develop statistical skills in network and dyadic data analysis; and 4) enhance knowledge of family-based interventions methods and theory. The candidate's training and research plan will provide the skills and preliminary data for Dr. Denison to pursue funding and successfully become an independent researcher in mindfulness and family-based mindful approaches to improve self-management among chronically ill adolescents.

描述（由申请人提供）：拟议的指导研究科学家职业发展奖（K01）的目的是促进丹尼森博士作为正念研究的独立科学家的发展，重点是基于家庭的正念方法，以支持青少年的艾滋病毒结果艾滋病毒感染者 (ALHIV) 的药物依从率较低，增加了艾滋病毒相关发病率和死亡率的风险，目前提高依从性的策略（例如同伴小组会议和依从性咨询）依赖于教育和认知方法。通常以个人行为改变为目标，而不涉及艾滋病毒管理发生的家庭和社会背景，该职业发展奖通过检查是否向 ALHIV 和成年家庭护理人员提供正念，以思想意识而不是改变思想内容来挑战这一范式，支持马里兰州巴尔的摩市 ALHIV 患者的自我调节和药物依从性行为。该研究的具体目的是：(1) 评估 R01 中 191 名参与者的家庭支持网络。告知家庭照顾者的定义和目标 2 的参与者选择和 3. (2) 通过对 20 名 ALHIV 和 20 名成年家庭成员进行定性深入访谈，检查 MBSR 对家庭支持关系和两代人 MBSR 干预措施的影响；(3) 检查可接受性和可行性；在 25 名 ALHIV 患者和成年家庭成员中进行试点 MBSR 干预，通过增加家庭支持来提高青少年对 ART 的依从性。约翰霍普金斯大学是这项拟议培训的理想环境，候选人将在整个获奖过程中获得高级教师的指导。导师和咨询委员会成员在正念研究和与在青少年群体中实施正念相关的主题（例如青少年健康、统计方法和基于家庭的干预措施）方面具有专业知识，通过结合定向阅读、课程作业和监督研究机会，这种指导。团队将支持 Denison 博士实现她的培训目标：(1) 获得正念理论、干预措施和研究方法方面的专业知识；(2) 完善和测试基于两代正念的减压干预措施；(3) 发展网络统计技能；和二元数据分析；以及4)增强对基于家庭的干预方法和理论的了解。候选人的培训和研究计划将为丹尼森博士提供技能和初步数据，以寻求资助并成功成为正念和基于家庭的正念方法的独立研究员，以改善自我管理。在患有慢性病的青少年中。