GERIATRIC EXERCISE TRAINING FOR FITNESS (GETFIT)

老年健身运动训练 (GETFIT)

• 批准号: 7608132
• 负责人: KRISANN K OURSLER
• 金额: $ 1.98万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608132
• 关键词: Acquired Immunodeficiency Syndrome; Adult; Aerobic; Age; Aging; American; Body Composition; Complex; Computer Retrieval of Information on Scientific Projects Database; Cross-Sectional Studies; Disease; Elderly; Exercise; Funding; Grant; Gray unit of radiation dose; HIV; Individual; Institution; Intervention; Numbers; Patients; Performance; Physical Function; Population; Rehabilitation therapy; Research; Research Personnel; Resources; Source; Training; United States National Institutes of Health; age effect; age related; aged; antiretroviral therapy; fitness; outcome forecast

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The number of Americans over age 50 with AIDS has increased more than 5-fold. Older adults with HIV have a worse prognosis than their younger counterparts. With advances in antiretroviral therapy, and the graying of the population, the number of HIV-infected older Americans will increase even further, clearly defining a need for age-related interventions. Little is known about the impact of age on functional performance in HIV-infected individuals and whether exercise training can ameliorate the marked physical deconditioning in older HIV-infected patients. Results from the proposed research will begin to identify the critical factors in the complex relationship of aging, HIV, and comorbid disease and their effect on physical functioning. We will conduct a cross-sectional study of 90 HIV-infected adults aged 21 to 50+ years to determine the effect of aging on physical functioning (peak aerobic capacity) and body composition in HIV-infected adults. We hypothesize that older HIV-infected individuals have an accelerated decline in physical functioning that is in part modifiable with exercise rehabilitation interventions.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 50 岁以上的美国人患有艾滋病的人数增加了 5 倍多。感染艾滋病毒的老年人比年轻人的预后更差。随着抗逆转录病毒疗法的进步和人口老龄化，感染艾滋病毒的美国老年人数量将进一步增加，这清楚地表明需要采取与年龄相关的干预措施。关于年龄对艾滋病毒感染者功能表现的影响以及运动训练是否可以改善老年艾滋病毒感染者明显的身体机能失调，人们知之甚少。拟议研究的结果将开始确定衰老、艾滋病毒和共病疾病之间复杂关系的关键因素及其对身体功能的影响。我们将对 90 名年龄在 21 岁至 50 岁以上的 HIV 感染者进行横断面研究，以确定衰老对 HIV 感染者的身体机能（峰值有氧能力）和身体成分的影响。我们假设老年艾滋病毒感染者的身体机能加速下降，这在一定程度上可以通过运动康复干预来改变。