NEI CENTER CORE GRANT FOR VISION RESEARCH

NEI 中心视觉研究核心资助

• 批准号: 9336307
• 负责人: BELA ANAND-APTE
• 金额: $ 63.4万
• 依托单位: CLEVELAND CLINIC LERNER COM-CWRU
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2021-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9336307
• 关键词: Affect; Anterior; Basic Science; Blindness; Center Core Grants; Cilia; Clinic; Collaborations; Conflict (Psychology); Core Grant; Cornea; Data; Development; Disease; Ectopia Lentis; Eligibility Determination; Environment; Epithelial; Equipment; Event; Extracellular Matrix; Eye; Faculty; Fostering; Funding; Generations; Goals; Grant; Health Services Accessibility; Health Services Research; Image; Immunity; Individual; Informatics; Institutes; Institution; Keratin; Keratitis; Laboratories; Liver; Molecular; Patients; Performance; Photoreceptors; Productivity; Research; Research Infrastructure; Research Personnel; Research Support; Resolution; Resources; Retina; Role; Scientist; Series; Services; Structure; Supervision; Support Groups; Techniques; Technology; Translational Research; Vision; Vision research; Visual system structure; base; cost; cost effective; data acquisition; elastography; equipment acquisition; human disease; instrumentation; models and simulation; mouse model; new technology; operation; prevent; programs; ranpirnase; retina blood vessel structure; skills

The overall aim of this NEI Core Grant for Vision Research is to facilitate the application of important technologies in the analysis of the structure, function and disease mechanisms that affect the visual system. The long-term goal of the investigators served by this grant is to preventing blindness and restoring vision. To this end we will develop a series of core modules that will provide state-of-the-art instrumentation and technologies required for vision research. The three core modules are: (1) Ocular Imaging Module; (2) Functional Vision Module; and (3) Molecular Informatics Module. These modules contain equipment that will be maintained and operated by highly skilled technicians that are supervised by established R01 funded investigators. Consolidating these technologies into these modules allow us to bring these techniques and skills to all potential users in our program, which we anticipate will increase productivity in the user laboratories and avoid duplication of equipment and effort. Successful operation of these three modules will bring the best of these technologies to each of the NEI RO1 supported laboratories in this institution. We also envision that these core modules will enhance and sustain the collaborative scientific environment that is a strong feature of the research group supported by these modules. The modules will also enhance productivity and increase collaboration among the participating investigators. These modules will also allow junior investigators to have access to services and research strategies that will help generate preliminary data to support new RO1 application.

这项NEI核心赠款对视觉研究的总体目的是促进应用 在结构，功能和疾病分析中重要的技术 影响视觉系统的机制。调查人员服务的长期目标 这笔赠款是防止失明和恢复视力。为此，我们将发展 一系列核心模块将提供最新的仪器和 视力研究所需的技术。三个核心模块是：（1）眼 成像模块； （2）功能视觉模块； （3）分子信息学模块。 这些模块包含将由高技能维护和操作的设备 由既定R01资助的研究人员监督的技术人员。合并 这些模块中的这些技术使我们能够将这些技术和技能带给所有人 我们计划中的潜在用户，我们预计这将提高用户的生产率 实验室，避免重复设备和努力。这些成功的操作 三个模块将把这些技术中的最好的模块带入每个NEI RO1 该机构的支持实验室。我们还设想这些核心模块将 增强和维持协作科学环境，这是 这些模块支持的研究小组。模块也将增强 生产力并提高参与研究人员之间的协作。这些 模块还将允许初级调查人员获得服务和研究 将有助于生成初步数据以支持新的RO1应用程序的策略。