BIOINFORMATICS CORE

生物信息学核心

• 批准号: 8716057
• 负责人: Benjamin L King
• 金额: $ 99.65万
• 依托单位: MOUNT DESERT ISLAND BIOLOGICAL LAB
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8716057
• 关键词: Bioinformatics; Biological; Biomedical Research; Collaborations; Computer Analysis; Consult; Consultations; Data Set; Data Storage and Retrieval; Delaware; Educational workshop; Faculty; Goals; Institution; Maine; Mentors; MicroRNAs; NCI Scholars Program; New Hampshire; Research; Research Personnel; Research Project Grants; Research Support; Research Training; Rhode Island; Series; Services; Students; Technical Expertise; Technology; Training; Vermont; Work; comparative; computer infrastructure; cyber infrastructure; data management; experience; functional genomics; innovation; novel; tool

The Maine IDeA Network for Biomedical Research Excellence (ME-INBRE) Bioinformatics Core will support research in comparative functional genomics by providing essential consulting and training in data management, bioinformatic and statistical analysis. Biomedical research increasingly utilizes highthroughput technologies, and the Core will provide specialized expertise to faculty and their students for managing, analyzing and interpreting results from large data sets. Highly experienced Core staff will provide consultation services, as well as access to analysis tools and computational infrastructure, to support analysis workflows. Analysis tools include the innovative miRMiner tool developed by Core staff to analyze known and novel microRNAs. The Bioinformatics Core will leverage regional collaborations and cyberinfrastructure through the Northeast Cybennfrastructure Consortium (NECC) that ME-INBRE cofounded with four other IDeA states to expand regional cyberinfrastructure and conduct collaborative cyberenabled research. Through the Northeast Bioinformatics Collaborative (NEBC), the Core will work with INBRE Bioinformatics Core staff in Delaware, New Hampshire, Rhode Island, and Vermont on consulting projects to support Maine faculty and collaborate on delivering bioinformatics training to faculty and students. Regional cyberinfrastructure will be used for intensive computations and centralized data storage, sharing and backup. A series of bioinformatics workshops will be given both within Maine and also regionally through the NEBC to provide research training to ME-INBRE Investigators, Research Training Faculty, and students, along with other Maine faculty and students. The Core will also host the new Bioinformatics Scholars Program to provide individually mentored bioinformatics research projects for students at MEINBRE institutions. In summary, the Core will provide the intellectual and technical expertise and training in bioinformatics that ME-INBRE Investigators and Research Training Faculty need to accomplish their research goals.

缅因州生物医学研究卓越研究网络（ME-INBRE）生物信息学核心将支持 通过在数据中提供必要的咨询和培训，对比较功能基因组学的研究 管理，生物信息学和统计分析。生物医学研究越来越多地利用了高通量 技术，核心将为教师及其学生提供专业的专业知识 管理，分析和解释大型数据集的结果。经验丰富的核心人员将提供 咨询服务以及获得分析工具和计算基础架构的访问，以支持 分析工作流程。分析工具包括由核心人员开发的创新Mirminer工具来分析 已知和新颖的microRNA。生物信息学核心将利用区域合作和 通过东北Cybennfradstructure联盟（NECC）的网络基础设施，我企业共同创立了 与其他四个思想状态一起扩展区域网络基础设施并进行协作网络培养 研究。通过东北生物信息学合作（NEBC），核心将与 特拉华州，新罕布什尔州，罗德岛和佛蒙特州的Inbre BioInformatics核心人员在咨询 支持缅因州教职员工的项目，并协作为教师和学生提供生物信息学培训。 区域网络基础设施将用于密集计算和集中数据存储，共享 和备份。将在缅因州和区域内进行一系列生物信息学研讨会 通过NEBC，向我的研究培训提供研究培训，研究培训学院和 学生，以及其他缅因州的教职员工。核心还将托管新的生物信息学 学者计划为Meinbre的学生提供单独指导的生物信息学研究项目 机构。总而言之，核心将提供智力和技术专业知识和培训 我的生物信息学，我企业的研究人员和研究培训教师需要完成他们的生物信息学 研究目标。