Gender Identity and HIV Risk II

性别认同和艾滋病毒风险 II

• 批准号: 8063089
• 负责人: MICHAEL H MINER
• 金额: $ 62.03万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-30 至 2013-01-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8063089
• 关键词: AIDS prevention; Address; Affect; Alcohol or Other Drugs use; Alcohols; Anus; Area; Attitude; Behavior; Behavioral; Body Image; Characteristics; Companions; Computers; Control Groups; Data; Data Analyses; Data Collection; Development; Effectiveness; Enrollment; Ethics; Evaluation; Female; Future; Gender; Gender Identity; Gender Role; General Population; Goals; Grant; HIV; HIV Infections; Health; Healthy People 2010; Hormones; Individual; Injection of therapeutic agent; Internet; Intervention; Interview; Knowledge; Learning; Measures; Mediation; Methods; Minority; Modeling; Participant; Persons; Pharmaceutical Preparations; Play; Population; Population Heterogeneity; Prevention Research; Prevention education; Preventive Intervention; Procedures; Public Health; Qualitative Research; Randomized Controlled Trials; Recruitment Activity; Reporting; Research; Research Personnel; Respondent; Risk; Risk Behaviors; Role; Rural; Sampling; Self Efficacy; Sex Behavior; Sex Orientation; Sexual Health; Sexual Partners; Silicones; Stigmata; Surveys; Target Populations; Testing; Time; United States; United States National Institutes of Health; Unsafe Sex; Vagina; Vulnerable Populations; Woman; Women' s Role; Work; base; behavior change; cofactor; condoms; cost; design; experience; follow-up; health disparity; high risk; high risk behavior; improved; innovation; instrument; interest; knowledge base; male; men; peer; programs; prototype; response; safer sex; satisfaction; self esteem; sex; social stigma; success; theories; therapy design; therapy development; transgender; transmission process; virtual

DESCRIPTION (provided by applicant): This application is a revised submission for a 5-year competitive continuation to grant 1R01-DA015269, Gender Identity and HIV Risk. The long-range goal of our research is to reduce HIV transmission among individuals stigmatized for their gender nonconformity and diversity, a goal consistent with the Healthy People 2010 objective to reduce the nation's health disparities. Key findings from our prior work were: a) a national sample of these individuals can be effectively reached via the Internet; b) differences in sex, gender identity/role, and sexual orientation are associated with important differences in HIV risk behavior; c) individuals in the female role are particularly vulnerable to HIV infection through the high risk behavior of the men with whom they interact. We propose to build on these findings by investigating the HIV risk behavior and cofactors of this population's high risk male partners (N=400), using online survey and interview methods successfully applied in the original project (Aim 1). These results will help inform the development of a theory- driven, Internet-based, HIV prevention intervention for individuals who are stigmatized for their gender non- conformity (Aim 2). The intervention will be modeled on an offline HIV intervention shown, in an uncontrolled trial, to reduce risk behavior in the target population. After user-testing and refinement of the prototype online intervention, we will conduct a randomized controlled trial (N=600) to evaluate its efficacy in improving health and reducing HIV risk behavior (Aim 3). This study is innovative in that a) few interventions exist for this minority population and even fewer have been adequately evaluated; b) the intervention will combine HIV prevention and behavior change theories with principles of e-learning; c) the entire study will be implemented online. Our team is highly experienced in HIV prevention research with diverse and vulnerable populations, the benefits/challenges of Internet-based research (online recruitment, data collection, intervention adaptation), and sexual health theory and measures. The project has public health significance in that the minority population targeted for intervention is at high risk for HIV infection, and the men with whom they interact not only pose a risk to them, but also to the general population. If proven effective, the online intervention can be implemented with little additional cost to reduce gender-related HIV risks on a large scale, nationally and internationally, even among highly stigmatized groups.

描述（由申请人提供）：本申请是对5年竞争性延续的修订提交，以授予1R01-DA015269，性别认同和HIV风险。我们研究的远程目标是减少因性别不合格和多样性而受到污名化的个人的艾滋病毒传播，这是与《健康人》 2010年目标一致的目标，以减少国家的健康差异。我们先前工作的主要发现是：a）可以通过互联网有效地达到这些人的全国样本； b）性别，性别认同/角色和性取向的差异与艾滋病毒风险行为的重要差异有关； c）女性角色中的个人特别容易受到与与之互动的男性的高风险行为的影响。我们建议使用在原始项目中成功采用的在线调查和访谈方法（AIM 1），提出通过调查该人群高风险男性伴侣的艾滋病毒风险行为和辅助因子（n = 400）的基础（n = 400）。这些结果将有助于为基于互联网的艾滋病毒预防理论的艾滋病毒预防干预措施的发展提供信息，以针对因性别不符合性而受到污名的个人（AIM 2）。该干预措施将以在不受控制的试验中显示的离线HIV干预措施进行建模，以减少目标人群的风险行为。在用户测试和完善原型在线干预措施之后，我们将进行一项随机对照试验（n = 600），以评估其在改善健康和降低HIV风险行为方面的功效（AIM 3）。这项研究具有创新性，因为a）对这一少数群体的干预措施很少，对经过充分评估的干预措施甚至更少； b）干预将结合预防HIV和行为的理论与电子学习原则相结合； c）整个研究将在线实施。我们的团队在艾滋病毒预防研究方面具有丰富的经验，具有不同和脆弱的人群，基于互联网的研究的好处/挑战（在线招聘，数据收集，干预适应）以及性健康理论和措施。该项目具有公共卫生的意义，因为少数派针对干预的少数族裔对艾滋病毒感染有很高的风险，而与之相互作用的男人不仅对他们有风险，而且对普通人群构成风险。如果被证明有效，在线干预措施几乎没有额外的成本可以减少与性别相关的艾滋病毒风险，即使在国际上，即使在高度污名化的群体中也是如此。