Mechanisms of Retinal Vascular Permeability in Diabetes

糖尿病视网膜血管通透性的机制

• 批准号: 8166420
• 负责人: David Antonetti
• 金额: $ 21.54万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166420
• 关键词: Advanced Glycosylation End Products; Alanine; Biochemical; Blindness; Blood Vessels; Blood-Retinal Barrier; CCL2 gene; Cattle; Cell Death; Cell Proliferation; Cell division; Cell membrane; Cells; Complex; Cytoplasm; Data; Development; Diabetes Mellitus; Diabetic Retinopathy; Disease; Dose; Elements; Endocytosis; Endosomes; Endothelial Cells; Epithelial; FDA approved; Figs - dietary; Functional disorder; Funding; Gene Deletion; Gene Expression; Goals; Golgi Apparatus; Growth Factor; Hyperglycemia; Hyperlipidemia; Hyperplasia; Immigration; Inflammatory; Integral Membrane Protein; Interleukin-1; Laboratories; Lead; Life; Link; Literature; Mass Spectrum Analysis; Measures; Medical; Metabolic; Molecular; Mus; Mutate; Mutation; Oxygen; Pathogenesis; Pathway interactions; Permeability; Phenotype; Phosphorylation; Phosphorylation Site; Proliferating; Protein Isoforms; Protein Kinase C; Proteins; Publishing; Rattus; Receptor Gene; Regulation; Research; Retina; Retinal; Retinal Diseases; Role; Signal Pathway; Signal Transduction; Site; Small Interfering RNA; Stomach; Structure of retinal pigment epithelium; Testing; Therapeutic; Therapeutic Intervention; Tight Junctions; Time; Tube; Tumor Necrosis Factor Receptor; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; Ubiquitination; United States; Vascular Endothelial Cell; Vascular Endothelial Growth Factors; Vascular Permeabilities; angiogenesis; atypical protein kinase C; base; cell growth; cellular imaging; comparative; cytokine; epsin; immunocytochemistry; in vivo; inhibitor/antagonist; macular edema; mutant; new therapeutic target; novel; novel therapeutics; occludin; overexpression; prevent; protein kinase C beta; public health relevance; research study; response; therapeutic target; trafficking