Approaches to Curtail Endometrial Cancer Incidence and Mortality

减少子宫内膜癌发病率和死亡率的方法

基本信息

批准号：
10796487
负责人：
Michele L. Cote
金额：
$ 2.7万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2023-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10796487
关键词：
Address African American population American Association of Cancer Research American Cancer Society Applications Grants Area Awareness Biology Cancer Control Cancer Survivor Cessation of life Classification Collaborations Continuance of life Country Coupled Data Development Diagnosis Disease Disparity Distress Early Diagnosis Endometrial Carcinoma Epidemiology Etiology Future Genetic Goals Gynecologic Oncology Hereditary Malignant Neoplasm Hereditary Neoplastic Syndromes Heterogeneity High Risk Woman Histologic Incidence Intake Intervention Knowledge Lead Malignant Female Reproductive System Neoplasm Malignant Neoplasms Manuscripts Methods Michigan Modeling Molecular Molecular Analysis Molecular Biology Molecular Epidemiology Monitor Morbidity - disease rate Not Hispanic or Latino Omega-3 Fatty Acids Oncology Outcome Pap smear Paper Pathology Population Heterogeneity Prevention Prognosis Publishing Quality of life Research Research Personnel Risk Reduction Seminal Stage at Diagnosis Survival Rate The Cancer Genome Atlas Time Uterine Cancer Uterine hemorrhage Uterus Woman Work anticancer research black women cancer risk clinical practice cohort dietary early detection biomarkers genetic association improved insight meetings metabolomics microbiome mortality multidisciplinary novel novel marker patient population racial disparity risk prediction survivorship symposium tumor tumor DNA

项目摘要

ABSTRACT Endometrial cancer incidence rates continue to rise, and it is the most common gynecologic cancer among women in the US. Distressingly, unlike most other cancers, the survival rates have been stagnant over the last several decades. There is a significant racial disparity in survival, with non-Hispanic black women having the poorest outcomes regardless of stage at diagnosis or histologic subtype. The reasons for this disparity, as well as other gaps in knowledge, such as approaches to monitor high risk women, or understanding survivorship issues, stand in the way of reducing the burden of endometrial cancer. This symposium will bring together experts from the fields of epidemiology, biology, pathology, oncology, genetics, and clinical practice to exchange knowledge and ideas. The discussions generated at and from this symposium will guide research to reduce incidence, morbidity and mortality from this disease. We plan a two-day symposium to be held in Detroit, Michigan, in June 2020. There will be seven sessions on specific topics, each with three to four speakers and a discussion leader. At the end of the second day, there will be group discussion sessions to develop priorities for future research that will identify the research initiatives that will have the greatest impact on reducing risk and improving survival from this common disease.

抽象的子宫内膜癌发病率持续上升，是最常见的妇科癌症美国的女性。令人痛苦的是，与大多数其他癌症不同，生存率在过去几年一直停滞不前几十年。生存方面存在显着的种族差异，非西班牙裔黑人女性的生存率无论诊断阶段或组织学亚型如何，结果都是最差的。造成这种差距的原因还有由于其他知识差距，例如监测高危妇女的方法或了解幸存者的方法问题，阻碍减轻子宫内膜癌的负担。本次研讨会将汇聚来自流行病学、生物学、病理学、肿瘤学、遗传学和临床实践领域的专家交流知识和想法。本次研讨会上产生的讨论将指导研究减少这种疾病的发病率、发病率和死亡率。我们计划于 2020 年 6 月在密歇根州底特律举行为期两天的研讨会。将有七场会议具体主题，每个主题有三到四名发言人和一名讨论主持人。第二天结束时，有将进行小组讨论，以确定未来研究的优先事项，从而确定研究将对降低这种常见疾病的风险和提高生存率产生最大影响的举措。