CHOICES-TEEN: Efficacy of a Bundled Risk Reduction Intervention for Juvenile Justice Females

CHOICES-TEEN：针对青少年司法女性的捆绑风险降低干预措施的功效

• 批准号: 10796649
• 负责人: Danielle Elizabeth Parrish
• 金额: $ 9.92万
• 依托单位: BAYLOR UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-15 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10796649
• 关键词: Adolescent; Affect; Alcohols; Behavior; Collection; Complex; Data; Data Analyses; Equation; Evidence based intervention; Exposure to; Female; Goals; Growth; HIV/STD; Health; Imprisonment; Intervention; Intervention Studies; Interview; Justice; Life Experience; Logistic Regressions; Manuscripts; Marijuana; Mediating; Mentorship; Modeling; Population; Pregnancy; Preparation; Prevention Research; Qualitative Research; Regression Analysis; Research; Research Personnel; Risk; Risk Behaviors; Risk Reduction; Suggestion; Teenagers; Testing; United States National Institutes of Health; clinical trial analysis; efficacy evaluation; efficacy testing; ethnic minority; experience; high risk; high risk sexual behavior; juvenile justice system; novel; parent grant; sexual risk behavior; skills; substance use; treatment arm; treatment effect; young woman

Project Summary/Abstract Parent Grant: Adolescent young women involved with juvenile justice settings engage in multiple health risk behaviors that place them at risk for HIV/STIs and pregnancy affected by alcohol and marijuana. This study aims to test the efficacy of CHOICES-TEEN (CT) in reducing the risks of substance-exposed pregnancy (SEP) and HIV/STIs among juvenile justice-involved young women. Proposed Diversity Supplement: While a substantive portion of justice- involved adolescent young women have been exposed to parental incarceration, and these adolescents were at higher risk of substance use and sexual risk behaviors, extant interventions for at-risk adolescents demonstrate limited effects on those with parental incarceration experiences. This diversity supplement aims to determine the efficacy of CT for adolescent young women with parental incarceration experiences by additional quantitative analyses of data collected by the parent grant and collection and analysis of qualitative interview data from a subsample with parental incarceration experiences following completion of the final 9-month assessment. Specifically, Aim 1 will utilize multilevel logistic regression analyses and latent growth curve modeling to determine the potential differential efficacy of CT in reducing the risks of SEP and HIV/STIs among adolescent young women who have experienced parental incarceration. In Aim 2, multilevel Bayesian structural equation modeling will be employed to evaluate the mediating treatment effects of the mechanisms of action for CT by parental incarceration. In Aim 3, qualitative interviews will be conducted with 20 adolescent young women in the intervention arm to explore their lived experiences of parental incarceration that may impact the efficacy and acceptability of CT and collect their suggestions for adaptations. The proposed diversity supplement research serves as a natural extension of the parent grant while offering a novel opportunity for a promising new investigator to initiate a new line of prevention research focused on adolescents with parental incarceration experiences and receive mentorship from a strong team of experienced researchers. This diversity supplement will help the candidate gain skills and experience in intervention research, complex quantitative analysis of clinical trial data, qualitative research, and manuscript preparation. Moreover, data from this study will inform a K01 application on developing new or adapted interventions (such as CT) for adolescents with parental incarceration experiences, with the long-term goal of testing its efficacy in a larger R01 study. This diversity supplement will significantly contribute to the candidate’s trajectory to becoming an independent NIH researcher.

项目摘要/摘要 父母赠款：参与青少年司法环境的青少年年轻妇女参与 多种健康风险行为，使他们面临艾滋病毒/性传播疾病的风险 酒精和大麻。这项研究旨在测试选择选择效率（CT） 少年司法司法公正的风险（SEP）和艾滋病毒/性传播疾病的风险 年轻女性。拟议的多样性补充：虽然司法大部分 涉及青少年的年轻妇女已经接触了父母的进化，这些 青少年的使用和性风险行为的风险更高，现有干预措施 对于高风险的青少年，对父母事件的人的影响有限 经验。这种多样性补充旨在确定CT对青少年的效率 父母影响经历的年轻妇女通过对 父母赠款和收集和分析定性访谈数据的数据 最后9个月完成后，具有父母演变经验的子样本 评估。特别是，AIM 1将利用多级逻辑回归分析和潜在 生长曲线建模，以确定CT在降低风险中的潜在差异效率 经历了父母的青少年年轻女性中的Sep和HIV/ETI 在AIM 2中，多级贝叶斯结构方程建模将被聘为 评估父母CT作用机理的中介治疗效果 在AIM 3中，将对20名青少年进行定性访谈 妇女在干预部门探索她们的现实父母事件经历 可能会影响CT的效率和可接受性，并收集其改编建议。 拟议的多样性补充研究是父母赠款的自然扩展 在为新的新调查员提供新的新线路的新范围的同时 预防研究的重点是具有父母伤害经历的青少年和 从一个有经验的研究人员团队中获得精神训练。这种多样性补充 将帮助候选人获得干预研究的技能和经验，复杂的定量 分析临床试验数据，定性研究和手稿准备。此外，数据 根据这项研究，将为K01申请开发新的或适应的干预措施（此类申请 作为CT）对于有父母监禁经历的青少年，其长期目标的 在较大的R01研究中测试其有效性。这种多样性补充将大大促进 候选人成为独立的NIH研究员的轨迹。