Enhancing SEBLAB Research Productivity, Operations and Core Laboratory Support

提高 SEBLAB 研究生产力、运营和核心实验室支持

基本信息

批准号：
10792750
负责人：
Sixto Manuel Leal
金额：
$ 269.17万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-18 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10792750
关键词：
Air Alabama Avian Influenza Award Biomedical Research COVID-19 pandemic Cell Culture Techniques Cell Line Cell Separation Cells Collaborations Containment Core Facility Coronavirus Decontamination Development Encephalitis Viruses Equilibrium Equine Encephalomyelitis Equipment Flow Cytometry Fostering Funding Histoplasma Human Resources In Vitro Individual Information Technology Institution Investments Laboratories Laboratory Research Leadership Maintenance Microbiology Mycobacterium tuberculosis National Institute of Allergy and Infectious Disease Occupational Medicine Organism Output Police Productivity Recovery Research Research Support Risk Scientist Security Services Solid Specialist Specimen Strategic Planning System Technology Training Training Programs Translating Translational Research Universities Venezuelan Equine Encephalomyelitis Work animal resource biobank biodefense career preparation chikungunya exhaust fungus future outbreak high resolution imaging high throughput screening imaging platform in vivo innovation laboratory facility medical countermeasure medical specialties new pandemic non-invasive imaging novel operation pandemic potential pandemic preparedness programs repaired research facility skills symposium training opportunity webinar

项目摘要

Project Summary The UAB Southeastern Biocontainment Laboratory (SEBLAB) is one of 12 Regional Biocontainment Laboratories (RBL) established by NIAID to advance BSL-3 research and pandemic preparedness. In continuous operation since 2009, NIAID award 1G20AI167409-01 enabled the repair of natural wear and tear on non- scientific equipment and essential upgrades to air balance, exhaust, energy recovery, and decontamination systems. Subsequently, NIAID award 1G20AI167409-S1 enabled the acquisition of cutting edge scientific equipment. The current proposal outlines a strategic plan to safely and effectively translate these investments into increased research productivity and innovative ground-breaking scientific discoveries. Core-1 outlines facility operations support, personnel support, and replacement of essential basic scientific equipment required for SEBLAB to foster safe and productive high containment research programs. Core-2 seeks to support a solid and effective biosafety workforce, external training opportunities, and development and implementation of high quality internal training programs critical to the safe execution of high containment research. Core-3 outlines a strategic plan to establish integrated core services within containment enabling the safe and efficient use of cutting edge technologies, optimized research productivity, and ground-breaking scientific innovation/s. Upon completion, this project will achieve the following: 1) Support SEBLAB facility operational expenses; 2) Fund the leadership, administrative, and technical staff required to operate this high complexity facility, 3) Replace existing basic scientific equipment, 4) Support high quality BSL-3 biosafety training, 5) Establish integrated research cores within high containment, 6) Optimize and boost SEBLAB scientific research productivity, 7) Foster RBL/NBL network collaboration, and 8) Fund and maintain a highly skilled BSL-3 scientific workforce ready to rapidly respond at the frontline of emerging pandemic threats.

项目摘要 UAB东南生物疗养实验室（SEBLAB）是12个区域生物植物之一 NIAID建立的实验室（RBL）可以推进BSL-3研究和大流行准备。连续自2009年以来的操作，NIAID奖1G20AI167409-01使得对非 - 非自然磨损的维修科学设备和基本升级以空气平衡，排气，能量恢复和净化系统。随后，NIAID奖1G20AI167409-S1实现了尖端科学的收购设备。当前的提案概述了安全有效地翻译这些投资的战略计划提高研究生产率和创新的开创性科学发现。 CORE-1大纲设施运营支持，人员支持以及更换必需的基本科学设备为了使Seblab培养安全和高效的高遏制研究计划。 Core-2试图支持坚实的以及有效的生物安全劳动力，外部培训机会以及高度发展和实施高质量的内部培训计划对于安全执行高遏制研究至关重要。 Core-3概述a 战略计划在遏制中建立综合核心服务，以实现安全有效的利用最先进的技术，优化的研究生产率和开创性的科学创新。之上完成，该项目将实现以下内容：1）支持Seblab设施运营费用； 2）资助领导，行政和技术人员需要经营这种高复杂性设施，3）替换现有基本科学设备，4）支持高质量的BSL-3生物安全培训，5）建立综合研究核心在高遏制之内，6）优化和增强Seblab科学研究生产力，7）寄养 RBL/NBL网络协作，8）资助并维持一支高技能的BSL-3科学劳动力队伍在新兴的大流行威胁的一线方面迅速做出回应。