BSL-3 Practices Core

BSL-3 实践核心

基本信息

批准号：
10793954
负责人：
Ying Kong
金额：
$ 33.6万
依托单位：
UNIVERSITY OF TENNESSEE HEALTH SCI CTR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-08-18 至 2028-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10793954
关键词：
Accountability Animals Area Aromatase Biochemistry Certification Collaborations Communication Competence Containment Dedications Development Emerging Communicable Diseases Engineering Ensure Equipment Equipment and supply inventories Faculty Focus Groups Funding Goals Growth Health Sciences Human Resources Immunology Individual Institution Investments Laboratories Laboratory Study Medicine Microbiology Mission Persons Pharmacy facility Productivity Protocols documentation Research Research Personnel Research Support Safety Secure Security Services Site Visit Specialist Tennessee Training United States National Institutes of Health Universities Viral Wages Work biodefense biosecurity college instrumentation laboratory facility member operation pandemic disease pandemic preparedness pandemic response pathogen professional atmosphere programs promote resilience research facility working group

项目摘要

PROJECT ABSTRACT The University of Tennessee Health Science Center (UTHSC) Regional Biocontainment Laboratory (RBL) mission is to maintain a facility for research that requires biosafety level-3 (BSL-3) or animal (ABSL-3) containment. The UTHSC RBL has the appropriate management team, staff, engineering controls, equipment, and facilities to support bacterial, viral, and fungal research programs necessitating BSL-2, BSL-3, ABSL-2 and ABSL-3 containment; however, the mission of the RBL is to facilitate BSL-3 and ABSL-3 research. As an NIH funded facility, the priority for use of the facility is for those with NIH funding requiring BSL-3 or ABSL-3 containment. Hence, the BSL-3 Practices Core is a cornerstone of all facility management, operations and research-related activities that take place in the UTHSC RBL. The rationale for having a BSL-3 Practices Core is (1) that it will integrate the management of operations and training for BSL-3 pathogens of which some are select agents, (2) promotes communication between Research Safety Affairs, UTREC (UTHSC Regional Biocontainment Laboratory Executive Committee) and the RBL Managers, and (3) harmonize compliance, security, individual competency, and practices across our RBL Staff and our users. Hence this will increase efficiency of services provided for the BSL-3 practices. The major aims and goals for the BSL-3 Practices Core in this UC7 application are as follows. This core is significant as biosafety, biosecurity, and BSL-3 practices for BSL-3 research is integrated into every aspect of the UTHSC RBL and is critical and essential for its function. The objectives of the BSL-3 Practices Core are to: Objective 1. To enhance the efficiency of the UTHSC RBL in its support of research programs and enhance the research productivity of the investigators who may use the RBL; Objective 2. Management and operation of the RBL BSL-3 Practices Core; and Objective 3. To ensure a safe and secure work environment within the RBL through training, provision of SOPs, support in development of SOPs, select agent inventory and accountability.

项目摘要田纳西大学健康科学中心 (UTHSC) 区域生物防护实验室 (RBL) 使命是维护需要生物安全 3 级 (BSL-3) 或动物安全 (ABSL-3) 的研究设施遏制。 UTHSC RBL 拥有适当的管理团队、员工、工程控制、设备、以及支持细菌、病毒和真菌研究项目的设施，这些项目需要 BSL-2、BSL-3、ABSL-2 和 ABSL-3 遏制；然而，RBL 的使命是促进 BSL-3 和 ABSL-3 研究。作为美国国立卫生研究院资助的设施，优先使用该设施的是那些拥有 NIH 资助且需要 BSL-3 或 ABSL-3 的人遏制。因此，BSL-3 实践核心是所有设施管理、运营和管理的基石。 UTHSC RBL 中进行的与研究相关的活动。拥有 BSL-3 实践核心的理由是 (1) 它将整合运营管理以及针对 BSL-3 病原体（其中一些是精选病原体）的培训，(2) 促进之间的交流研究安全事务、UTREC（UTHSC 区域生物防护实验室执行委员会）和 RBL 经理，(3) 协调整个 RBL 的合规性、安全性、个人能力和实践员工和我们的用户。因此，这将提高为 BSL-3 实践提供的服务的效率。主要此 UC7 应用程序中 BSL-3 实践核心的目的和目标如下。该核心的重要意义在于 BSL-3 研究的生物安全、生物保安和 BSL-3 实践已融入到 BSL-3 的各个方面 UTHSC RBL 对其功能至关重要且必不可少。 BSL-3 实践核心的目标是：目标 1. 提高 UTHSC 的效率 RBL 支持研究计划并提高研究人员的研究生产力使用 RBL；目标 2. RBL BSL-3 实践核心的管理和运营；和目标 3. 至通过培训、提供标准操作程序、提供支持，确保 RBL 内有一个安全可靠的工作环境制定标准操作程序、选择代理库存和问责制。