Psychosocial Stress Due to COVID-19 and Vascular Aging in African-American Women

COVID-19 造成的心理社会压力和非裔美国女性的血管老化

基本信息

批准号：
10792341
负责人：
Tené T Lewis
金额：
$ 37.56万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-05-01 至 2025-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10792341
关键词：
2019-nCoV Academy Accountability African American African American population Aging Award Biometry Black race Blood Blood Pressure Blood Vessels Businesses COVID-19 COVID-19 disparity COVID-19 impact COVID-19 mortality COVID-19 pandemic COVID-19 stress Child Rearing Code Collaborations Coronavirus Dangerousness Data Disease Educational process of instructing Emotional Employment Exposure to Faculty Feedback Female Financial Hardship First Generation College Students Funding Gender Goals Health Heart Heterogeneity Inequality Inflammation Infrastructure Institution Life Loneliness Lung Manuscripts Marital Status Measurement Mental Health Mentors Mentorship Minority Modeling National Heart, Lung, and Blood Institute Occupations Personal Satisfaction Physiological Postdoctoral Fellow Prevention Principal Investigator Psychosocial Assessment and Care Psychosocial Stress Public Health Publications Race Reporting Research Research Personnel Resources SARS-CoV-2 infection Science Social isolation Social support Socioeconomic Status Stress Students Syndrome Taxes Time Training Underemployment Underrepresented Populations Unemployment Vascular Diseases Virus Vulnerable Populations Woman Work Writing arterial stiffness burnout career career development cohort coping data management design equity, diversity, and inclusion ethnic minority experience faculty mentor health equity infection rate innovation interest maltreatment meetings member mid-career faculty middle age mortality multi-ethnic multidisciplinary network models next generation novel coronavirus optimism pandemic disease pandemic stress parent grant peer peer coaching peer support physical conditioning professor prospective psychosocial psychosocial stressors racial difference racial disparity racial minority recruit resilience senior faculty social stressor sociodemographic factors stressor undergraduate student virtual

项目摘要

PROJECT SUMMARY The novel coronavirus disease 2019 (COVID-19) global pandemic was arguably one of the most devastating Public Health crises of the last century. In the US, African-Americans have been disproportionately impacted, with overall rates of infection and mortality 2 to 4 times higher than those observed in Whites. Additionally, as a direct result of closings of non-essential businesses and other entities, rates of unemployment and underemployment also surged, and African-Americans have been significantly more likely than Whites to report being underemployed or furloughed due to the pandemic. Unsurprisingly, given racial disparities in COVID-19 mortality, national polls also find racial differences in reports of COVID-related loss, with African- Americans more frequently reporting personally knowing someone who died from COVID-19 than Whites. Because of this, it has been argued that, as a result of COVID-19, African-Americans have been experiencing a “pandemic of stress” that will have a “dangerous impact” on their health and well-being long after the virus itself is contained. Leveraging our previously funded cohort that assessed psychosocial stress and vascular aging in early middle-aged African-American women, we will examine the degree to which stressors resulting from, and related to, the COVID-19 pandemic might impact vascular disease—the number 1 killer in the US-in this group. Middle-aged African-American women may be a uniquely important group on which to focus, because: 1) they have increasingly high, but poorly understood, rates of vascular disease relative to other race-gender groups; and 2) the long-term impact of the widespread financial, employment and social stressors resulting from COVID-19 might be particularly deleterious for this group, largely due to structural and contextual inequalities that pre-dated the pandemic itself. The proposed project will examine linkages between overall psychosocial stressors (debt, financial stress, job stress, interpersonal incivilities and mistreatment, loneliness), COVID-specific stressors (COVID-related financial difficulties, COVID-specific parenting stressors, COVID-related loss) and prospective changes in vascular aging (ambulatory blood pressure, arterial stiffness, inflammation) over 24 months in a cohort of 350 middle- aged African-American women. Because we have pre-COVID assessments of a range of psychosocial stressors, a major innovation of the proposed work is our ability to examine how pre- versus post- COVID changes in exposure to overall psychosocial stress might prospectively impact vascular aging. Importantly, we will capitalize on the considerable within-group heterogeneity in our cohort, to examine whether our hypothesized associations are moderated by sociodemographic factors that might increase vulnerability (socioeconomic status, single parenthood, marital status) or resilience (e.g., purpose in life, optimism, mastery, social support) to psychosocial stress, in order to inform short- and long-term prevention efforts.

项目摘要 2019年新型冠状病毒病（Covid-19）全球大流行可以说是最具破坏性的上个世纪的公共卫生危机。在美国，非裔美国人受到了不成比例的影响，总体感染率和死亡率比白人中观察到的高2至4倍。另外，作为关闭非必需企业和其他实体的直接结果，失业率和就业不足也激增，非裔美国人比白人更有可能报告由于大流行而导致就业不足或休假。毫不奇怪，鉴于赛车差异 COVID-19死亡率，国家民意调查还发现与共同相关损失的报告中的种族差异，非洲 - 美国人更频繁地报告亲自认识一个与白人相比，死于Covid-19的人。因此，有人认为，由于19号，非裔美国人一直是体验“压力大流行”，将对他们的健康和福祉产生“危险的影响” 病毒本身被包含很久之后。利用我们先前资助的人群评估心理社会的队列早期中年非裔美国妇女的压力和血管衰老，我们将研究该程度哪些由Covid-19大流行产生的压力源可能会影响血管疾病 - 该组美国的1号杀手。中年非裔美国妇女可能是要集中精力的独特重要群体，因为：1）他们越来越高，但理解不佳，相对于其他种族性别群体的血管疾病率； 2）宽度的长期影响 COVID-19产生的财务，就业和社会压力源可能会特别删除小组，主要是由于结构性和背景不平等，这些不平等现象是早期的大流行本身。提议项目将检查整体的社会心理压力源（债务，财务压力，工作压力，人际关系的疾病和虐待，孤独感），共同的压力源（与联盟相关的财务难度，共同的育儿压力源，与联想相关的损失）和血管的前瞻性变化衰老（卧床血压，动脉僵硬，炎症）在24个月内的350个中间年龄的非裔美国妇女。因为我们对一系列社会心理进行了预循环的评估压力源是对拟议工作的主要创新，我们的能力是研究前与后期的能力共同接触整体社会心理压力的变化可能会影响血管衰老。重要的是，我们将利用我们的队列中组内异质性的考虑，以检查是否是否是否进行检查我们的假设关联受到社会人口统计学因素的调节，这些因素可能会增加脆弱性（社会经济地位，单身父母身份，婚姻状况）或韧性（例如，生活，乐观，精通，掌握的目的社会支持）对社会心理压力，以告知短期和长期预防工作。