UCSF Older Americans Independence Center

加州大学旧金山分校美国老年人独立中心

• 批准号: 10729111
• 负责人: KENNETH E. COVINSKY
• 金额: $ 123.13万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10729111
• 关键词: Acceleration; Achievement; Address; Advance Care Planning; Affect; Aging; American; Area; Award; Capsicum; Caregivers; Caring; Clinical; Clinical Research; Collaborations; Communities; Complex; Consultations; Data; Data Sources; Dedications; Dermatology; Development; Diabetes Mellitus; Disabled Persons; Discipline; Education; Elderly; Enrollment; Ensure; Fostering; Funding; Future; Geriatrics; Goals; Guidelines; HIV; Healthcare; Homelessness; Hospitals; Impaired cognition; Imprisonment; Internet; Journals; Leadership; Malignant Neoplasms; Mentors; Mentorship; Mission; Neurology; Nursing Homes; Older Population; Oncology; Operative Surgical Procedures; Outcome; Outcomes Research; Patients; Persons; Pilot Projects; Policies; Poverty; Publications; Quality of life; Research; Research Methodology; Research Personnel; Research Support; Resources; Risk; Science; Screening for cancer; Social Interaction; Social isolation; Structure; Sum; Translating; Vulnerable Populations; Work; advanced disease; career development; clinical practice; community center; cost; data resource; disability; disability risk; experience; forging; improved; improved outcome; innovation; instrument; interdisciplinary collaboration; literacy; medical specialties; medical vulnerability; multiple chronic conditions; next generation; prevent; prognostic; programs; safety net; social vulnerability; success; therapy development; tool; user-friendly; web site; web-based tool

PROJECT SUMMARY ABSTRACT – Overall UCSF Older Americans Independence Center (OAIC) The UCSF OAIC theme is "Predictors, Outcomes, and Amelioration of Late-life Disability: A Focus on Vulnerable Populations." Late-life disability will affect 80% of older Americans, has a profound impact on patient and caregiver quality of life, and carries large costs. These challenges have special resonance for older adults who are vulnerable, which we conceptualize as a complex interplay of both medical vulnerability (such as cancer in persons with complex multimorbidity) and social vulnerability (such as social isolation or poverty). We are deeply committed to advancing the science of preventing and ameliorating disability in older adults with these vulnerabilities, in large part by mentoring and supporting the future leaders of aging science who will develop this theme. During our first 9 years, the UCSF OAIC has supported and mentored an interdisciplinary community of investigators whose paradigm-shifting research that has changed clinical practice and policy and yielded major advances in our understanding of disability, including elucidating inextricable linkages between medical and social vulnerabilities. We have been a galvanizing force at UCSF, infusing aging science into a wide array of specialties and disciplines. Our dedication to developing the next generation of researchers has led to publications in the highest impact journals, R01 awards, an unprecedented number of GEMSSTAR and Beeson Awards, and mentorship awards for OAIC Leaders. During the next cycle, we will build on our track record of success while growing and innovating in new directions to respond to emerging opportunities. Our two resource cores – the Data and Analysis Core (DAC) and the Vulnerable Aging Research Core (VARC) - will catalyze a wide spectrum of clinical and outcomes research. Our Research and Education Component (REC) Scholars and Pilot and Exploratory Studies (PESC) Scholars will be provided the resources, mentorship, and community to build a platform for long-term research success in our theme area. Our Leadership and Administration Core (LAC) will guide the Center's activities and mission and ensure tight integration between all of our Cores and activities. Together, we will advance our center's 5 aims: to (1) Catalyze research on disability in vulnerable older persons by serving as a hub that brings together scholars and leverages resources to advance aging disability science and career development; (2) Provide core access to data resources, statistical support, and expertise enrolling and retaining vulnerable older subjects in order to stimulate new research on disability; (3) Identify the future leaders of geriatrics research and catalyze their development with career development funding and exceptional mentoring; (4) Support pilot studies that accelerate aging science and lead to research funding in late life disability; and (5) Develop a leadership and administrative structure that spurs interdisciplinary collaboration, making the OAIC greater than the sum of its parts.

项目摘要 摘要 – 整体 UCSF 年长美国人独立中心 (OAIC) UCSF OAIC 的主题是“晚年残疾的预测因素、结果和改善：关注 弱势群体。”晚年残疾将影响 80% 的美国老年人，对 这些挑战会影响患者和护理人员的生活质量，并带来巨大的成本。 脆弱的成年人，我们将其概念化为医疗脆弱性（例如 例如患有复杂多发病的癌症）和社会脆弱性（例如社会孤立或贫困）。 我们坚定致力于推进预防和改善老年人残疾的科学 这些脆弱性在很大程度上是通过指导和支持老龄科学的未来领导者来实现的，他们将 在我们成立的头 9 年里，UCSF OAIC 支持并指导了一个跨学科的项目。 研究者群体，他们的范式转变研究改变了临床实践和政策， 在我们对残疾的理解方面取得了重大进展，包括阐明了残疾之间不可分割的联系 我们一直是加州大学旧金山分校的一股激励力量，将老龄科学融入到社会中。 我们致力于培养下一代研究人员。 导致在最具影响力的期刊、R01 奖、空前数量的 GEMSSTAR 和 Beeson 奖和 OAIC 领导人导师奖。 在下一个周期中，我们将在取得成功的基础上继续发展和创新 我们的两个资源核心——数据和分析核心（DAC） 和脆弱老化研究核心（VARC）——将促进广泛的临床和结果 我们的研究和教育部分（REC）学者以及试点和探索性研究（PESC） 将为学者提供资源、指导和社区，以建立长期研究的平台 我们的领导和管理核心 (LAC) 将指导中心的活动。 和使命，并确保我们所有核心和活动之间的紧密结合，我们将共同推进我们的发展。 该中心的 5 个目标： (1) 作为一个中心，促进对弱势老年人残疾问题的研究 汇集学者并利用资源来推进老年残疾科学和职业发展； (2) 提供获取数据资源、统计支持以及招收和留住弱势群体的专业知识的核心途径 老年学科，以促进有关残疾的新研究；（3）确定老年病学的未来领导者 通过职业发展资金和特殊指导来研究和促进他们的发展（4） 支持加速衰老科学并为晚年残疾提供研究经费的试点研究；以及 (5) 建立促进跨学科合作的领导和管理结构，使 OAIC 大于其各部分之和。

项目成果

Cancer Screening in Older Adults: Individualized Decision-Making and Communication Strategies.

• DOI: 10.1016/j.mcna.2020.08.002
• 发表时间: 2020-11
• 期刊: The Medical clinics of North America
• 作者: Kotwal AA;Walter LC
• 通讯作者: Walter LC

Antihypertensive Medication and Fracture Risk in Older Veterans Health Administration Nursing Home Residents.

老年退伍军人健康管理局疗养院居民的抗高血压药物和骨折风险。

• DOI: 10.1001/jamainternmed.2024.0507
• 发表时间: 2024
• 期刊: JAMA internal medicine
• 影响因子: 39
• 作者: Dave,ChintanV;Li,Yongmei;Steinman,MichaelA;Lee,SeiJ;Liu,Xiaojuan;Jing,Bocheng;Graham,LauraA;Marcum,ZacharyA;Fung,KathyZ;Odden,MichelleC
• 通讯作者: Odden,MichelleC

The growing geriatric prison population: A dire public health consequence of mass incarceration.

• DOI: 10.1111/jgs.17454
• 发表时间: 2021-12
• 期刊: Journal of the American Geriatrics Society
• 影响因子: 6.3
• 作者: Williams B;DiTomas M;Pachynski A
• 通讯作者: Pachynski A

Long-term individual and population functional outcomes in older adults with atrial fibrillation.

患有房颤的老年人的长期个人和群体功能结果。

• DOI: 10.1101/2020.11.05.20223297
• 发表时间: 2020
• 期刊: medRxiv : the preprint server for health sciences
• 作者: Parks,AnnaL;Jeon,SunY;Boscardin,WJohn;Steinman,MichaelA;Smith,AlexanderK;Fang,MargaretC;Shah,SachinJ
• 通讯作者: Shah,SachinJ

Multi-level Factors Influencing Decisions About Stopping Surveillance Colonoscopy in Older Adults: a Qualitative Study.

• DOI: 10.1007/s11606-023-08225-0
• 发表时间: 2023-09
• 期刊: JOURNAL OF GENERAL INTERNAL MEDICINE
• 影响因子: 5.7
• 作者: Schifferdecker, Karen E.;Ramesh, Nithya Puttige;Walter, Louise C.;Calderwood, Audrey H.
• 通讯作者: Calderwood, Audrey H.