Research Core

研究核心

基本信息

批准号：
7685683
负责人：
PAUL B JACOBSEN
金额：
$ 13.21万
依托单位：
UNIVERSITY OF SOUTH FLORIDA
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-05-08 至 2013-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7685683
关键词：
Address African American Arts Awareness Behavioral Biological Markers Biostatistics Core Cancer Center Cancer Etiology Caucasians Caucasoid Race Collaborations Communication Communities Community Health Education Data Analyses Development Devices Discipline Disease Economics Education and Outreach Effectiveness Elements Ensure Epidemiology Etiology Evaluation Extramural Activities Faculty Fostering Foundations Funding Grant Health Personnel Institutes Institution Intervention Investigation Isoflavones Joints Knowledge Malignant Neoplasms Malignant neoplasm of prostate Medicine Mentors Methodology Modeling Molecular Molecular Carcinogenesis Patients Phase II Clinical Trials Pilot Projects Population Public Health Research Research Activity Research Design Research Infrastructure Research Personnel Research Project Grants Research Training Resource Sharing Safety Sample Size Science Scientist Screening for Prostate Cancer Series Services Staging Survey Methodology Training Training and Education Translational Research Underrepresented Minority Ursidae Family Work aptamer base cancer health disparity cancer prevention career college community based participatory research design effectiveness research evidence base experience health disparity health economics innovation insight instrument interest men minority health nanoscale novel outreach pilot trial post-doctoral training programs research study safety testing skills social success survivorship training project

项目摘要

The Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities will serve as the hub responsible for connecting and overseeing the proposed research activities and fostering new projects. Our overarching theme is to generate new knowledge aimed at understanding and addressing cancer-related health disparities among underserved and minority populations. We will do so with an emphasis on 1) understanding the bio-behavioral etiology of cancer-related health disparities, and 2) developing and testing the safety and efficacy of novel transdisciplinary interventions to reduce, and ultimately eliminate, these disparities. We propose to establish this collaborative enterprise based on similar programs that have been developed and implemented in the two respective institutions to address cancer-related health disparities. Specifically, this effort builds on the significant success of research conducted as part of our existing Tampa Bay Community Cancer Network (PI: Meade C, NIH-NCI), Patient Navigator Program (PI: Roetzeim R, NIH-NCI), and the FAMU-MCC Partnership Research and Training Grant (Pis: Odedina F and Kumar NB, DOD). Disentangling the myriad determinants of a disease such as cancer, within the context of minority health or health disparities, requires a transdisciplinary approach. Transdisciplinary approaches draw on concepts from multiple scientific disciplines to develop a novel, integrated perspective from which to conduct scientific investigation. Advances in transdisciplinary research on cancer health disparities may be impeded if socio-behavioral and bio-molecular determinants of disparities are not explored in an integrated fashion. We therefore propose to use a socio-biologic organizing model that encourages a multilevel, integrative perspective in the study of cancer disparities (Gibbons et al, 2007). By utilizing the existing research infrastructure of the Moffitt Cancer Center's scientific programs, core services and shared resources to facilitate and strengthen collaborations between Moffitt-based investigators and investigators in the USF Colleges of Medicine, Public Health, and Arts and Sciences, this collaborative Research Core of the USF/Moffitt Transdisciplinary Center of Excellence to Address Cancer Health Disparities is poised to address and eliminate cancer-related health disparities.

南佛罗里达大学/莫菲特跨学科卓越中心解决癌症健康问题的研究核心 Disparities 将作为负责连接和监督拟议研究活动的枢纽并培育新项目。我们的首要主题是产生旨在理解和理解的新知识解决服务不足和少数民族人口中与癌症相关的健康差异。我们将这样做强调 1) 了解癌症相关健康差异的生物行为病因学，以及 2) 开发和测试新型跨学科干预措施的安全性和有效性，以减少并最终减少消除这些差异。我们建议在类似项目的基础上建立这个合作企业两个机构分别制定和实施了解决与癌症相关的健康问题差异。具体来说，这项工作建立在我们的研究取得重大成功的基础上现有坦帕湾社区癌症网络（PI：Meade C、NIH-NCI）、患者导航计划（PI： Roetzeim R，NIH-NCI），以及 FAMU-MCC 合作研究和培训补助金（Pis：Odedina F 和库马尔 NB，国防部）。在以下背景下理清癌症等疾病的无数决定因素少数民族的健康或健康差异，需要采取跨学科的方法。跨学科方法绘制来自多个科学学科的概念，以发展一种新颖的、综合的视角进行科学调查。关于癌症健康差异的跨学科研究的进展可能是如果不综合探讨差异的社会行为和生物分子决定因素，就会受到阻碍时尚。因此，我们建议使用社会生物学组织模型，鼓励多层次、癌症差异研究中的综合视角（Gibbons 等，2007）。通过利用现有的研究莫菲特癌症中心的科学项目、核心服务和共享资源的基础设施促进和加强莫菲特研究人员与南佛罗里达大学研究人员之间的合作医学院、公共卫生学院、艺术与科学学院，这个合作研究核心南佛罗里达大学/莫菲特跨学科卓越中心致力于解决癌症健康差异问题并消除与癌症相关的健康差距。