HIV/AIDS Clinical Trials Unit

艾滋病毒/艾滋病临床试验单位

• 批准号: 7556781
• 负责人: John A Bartlett
• 金额: $ 271.23万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7556781
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Academic Medical Centers; Accountability; Acquired Immunodeficiency Syndrome; Acute; Address; Adult; African American; Area; Award; Catchment Area; Child; Childhood; Clinical Management; Clinical Research; Clinical Trials; Clinical Trials Design; Clinical Trials Unit; Collaborations; Communication; Communities; Creativeness; Dimensions; Disease; Early Diagnosis; Ensure; Environment; Epidemic; Family; Foundations; Funding; Goals; HIV; HIV Infections; HIV Vaccine Trials Network; Hispanics; Human; IMPAACT; Immunology; Infection; International; International AIDS; Laboratories; Leadership; Letters; Life; Medical center; Mothers; National Institute of Allergy and Infectious Disease; North Carolina; Operative Surgical Procedures; Persons; Population; Positioning Attribute; Pregnant Women; Prevention; Procedures; Productivity; Public Health Schools; Recording of previous events; Recruitment Activity; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Priority; Research Training; Resource Sharing; Role; Safety; Site; Southeastern United States; Structure; Tanzania; Training; Translational Research; Underserved Population; United States; United States National Institutes of Health; Universities; Vertical Disease Transmission; Work; clinical practice; clinical research site; expectation; experience; flexibility; high standard; improved; international center; pediatric AIDS; programs; success

Composite The Duke University Medical Center (DUMC) Clinical Trials Unit (CTU) proposes to address the key scientific areas of translational research and optimization of clinical management in children and adults, and prevention of mother to child transmission.The CTU and its affiliated Clinical Research Sites (CRS's) bring scientific leadership, a rich history of successful collaborative clinical research within networks, a strong and efficient organizational foundation for the conduct of rigorous clinical research, and access to growing numbers of underserved persons living with HIV/AIDS (PLWHA) in the US Southeast and Tanzania. The scientific leadership of the CTU and CRS investigators is reflected in their past participation in the Adult and Pediatric AIDS Clinical Trials Groups (ACTG's), and the expanding portfolio of NIH-funded research at DUMC and the Kilimanjaro Christian Medical Centre (KCMC). The three CRS's included in the CTU proposal each bring unique value and are highly motivated to perform the proposed work, and together they will constitute a formidable research enterprise. Their interactions will be guided by an administrative structure which supports a dynamic intellectual environment to enhance scientific creativity, clear roles and responsibilities for investigators and staff, facile and regular communications, harmonized standard operating procedures across CRS's which emphasize CTU accountability through quality management, and a strong commitment to serve the community of PLWHA. The clarity of CTU and CRS organization and operations will ensure that it operates efficiently to perform clinical research at the highest standard, with the ability to rapidly respond to evolving opportunities.

合成的 杜克大学医学中心（DUMC）临床试验部（CTU）提议解决钥匙 转化研究和儿童临床管理优化的科学领域 成人，预防母亲传播的母亲。 网站（CRS）带来了科学领导，这是成功合作临床研究的丰富历史 在网络中，强大而有效的组织基础是进行严格的临床 研究，并获得越来越多的艾滋病毒/艾滋病（PLWHA）的人数越来越多的人 美国东南部和坦桑尼亚。 CTU和CRS调查人员的科学领导是 反映了他们过去参与成人和小儿艾滋病临床试验小组（ACTG）的参与 DUMC和乞力马扎罗基督教医学中心的NIH资助研究的扩大投资组合 （KCMC）。 CTU提案中包含的三个CRS每个都带来了独特的价值，并且很高 有动力执行拟议的工作，它们将共同构成一项强大的研究 企业。他们的互动将以支持动态的管理结构为指导 智力环境增强科学创造力，明确的角色和责任 调查人员和员工，便利和常规沟通，协调的标准操作 CRS的程序通过质量管理强调CTU问责制，A 致力于为PLWHA社区服务的坚定承诺。 CTU和CRS组织的清晰度以及 操作将确保其有效运行，以最高标准进行临床研究 具有迅速响应不断发展的机会的能力。