Bioinformatics, Statistical and Methodological Core

生物信息学、统计和方法论核心

基本信息

批准号：
10762212
负责人：
Gebre-Egziabher Kiros
金额：
$ 3.45万
依托单位：
FLORIDA AGRICULTURAL AND MECHANICAL UNIV
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-19 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10762212
关键词：
Achievement Address Advanced Malignant Neoplasm African American Bioinformatics Biological Biometry Black American California Cancer Research Project Cancer health equity Caring Clinical Communities Community Outreach Comprehensive Cancer Center Data Data Analyses Data Collection Data Management Resources Data Science Data Set Data Storage and Retrieval Databases Development Doctor of Philosophy E-learning Education Educational Materials Educational workshop Ensure Environmental Exposure Evaluation Event Florida Funding Future Gene Expression Profiling Goals Grant Health Health Disparities Research High-Throughput Nucleotide Sequencing Hispanic Individual Institution Laboratories Malignant Neoplasms Manuscripts Methodology Methods Mutation Mutation Analysis Occupations Pilot Projects Population Preparation Procedures Publications Quality Control Reproducibility Research Research Design Research Personnel Research Project Grants Resource Sharing Resources Schedule Science Series Services Source System Techniques Tissue Model Training Training Support Triage Underserved Population Universities University of Southern California Norris Cancer Center Work anticancer research cancer health disparity computerized data processing computing resources data cleaning data management data repository data sharing design drug development education research exome sequencing experimental study federated data genomic data health equity high dimensionality human data innovation lectures meetings member mortality novel outreach public database single cell sequencing software as a service software development transcriptome sequencing web site

项目摘要

ABSTRACT – BIOINFORMATICS, STATISTICAL AND METHODOLOGICAL CORE The primary goal of the Bioinformatics, Statistical, and Methodological (BSM) Core at the Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity Center is to provide the data management, data cleaning, data storage, and data release to public databases for all information generated by our Center. In addition, it will provide bioinformatics, statistical and methodological support for all the cancer research projects proposed, as well as future projects that will build upon them and disseminate to all CaRE2 Center members and the scientific community at large in a timely fashion. We will reach these goals through three aims: First, we will provide bioinformatics, statistical and methodological support. This first aim established the job scheduling and interfaces to meet the needs of all CaRE2 Health Equity Center investigators. We will support bioinformatics and statistical issues across the projects and cores. Bioinformatics support will include in-depth quality control and assessment of all high-throughput sequencing data from multiple platforms and facilitate access to publicly available datasets. Statistical and methodological support will consist of all aspects, from collecting to state-of- the-art data analysis and interpretation and abstract, manuscript, and grant preparation. The second aim will be enhancing and maintaining a federated data repository resource that enables the interaction of CaRE2 members. This second aim ensures that all data are of high quality and disseminated to all CaRE2 Center members and the scientific community promptly. In the third aim, we will provide bioinformatics, statistical and methodological support, and educational opportunities to the CaRE2 Center. This third aim focuses on developing online educational materials that BSMC's members and guest experts will present through the core events, such as seminar series and interactive lectures among all CaRE2 Center members.

摘要——生物信息学、统计学和方法论核心佛罗里达-加州生物信息学、统计和方法 (BSM) 核心的主要目标癌症研究、教育和参与 (CaRE2) 健康公平中心旨在提供数据管理、我们中心生成的所有信息的数据清理、数据存储以及数据发布到公共数据库。此外，它将为所有癌症研究项目提供生物信息学、统计和方法学支持提议的以及未来的项目，这些项目将以它们为基础并传播给所有 CaRE2 中心成员和我们将通过三个目标及时实现这些目标：首先，我们将第一个目标是提供生物信息学、统计和方法支持。满足所有 CaRE2 健康公平中心研究人员的需求我们将支持生物信息学和跨项目和核心的统计问题将包括深入的质量控制和评估来自多个平台的所有高通量测序数据并方便公开获取可用的数据集。统计和方法支持将包括从收集到现状的各个方面。第二个目标是最先进的数据分析和解释以及摘要、手稿和资助准备。增强和维护联合数据存储库资源，使 CaRE2 成员能够进行交互。第二个目标确保所有数据都是高质量的，并分发给所有 CaRE2 中心成员和迅速向科学界提供第三个目标，我们将提供生物信息学、统计和方法论。为 CaRE2 中心提供支持和教育机会第三个目标侧重于在线发展。 BSMC 的成员和客座专家将通过核心活动提供的教育材料，例如所有 CaRE2 中心成员之间的研讨会系列和互动讲座。