Childhood Obesity and Cardiometabolic Health among Impoverished Mexican Americans

贫困墨西哥裔美国人的儿童肥胖和心脏代谢健康

基本信息

批准号：
10707401
负责人：
LINDA J LUECKEN
金额：
$ 63.04万
依托单位：
ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-08-07 至 2027-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10707401
关键词：
10 year old 19 year old 5 year old Acculturation Acute Address Adolescence Affect Age Behavioral Biological Birth Blood Pressure Body mass index C-reactive protein COVID-19 impact COVID-19 pandemic Cardiovascular system Characteristics Child Child Mental Health Childhood Cholesterol Chronic Classification Climate Communities Country Data Data Collection Development Diabetes Mellitus Disadvantaged Discrimination Disease Eating Behavior Economics Effectiveness Environmental Risk Factor Ethnic Origin Ethnic Population Event Exposure to Family Funding General Population Glycosylated hemoglobin A Goals Growth Health Health Policy Health Status Heart Diseases Hispanic Hispanic Americans Hispanic Populations Infant Interleukin-6 Latino Life Longevity Longitudinal Studies Low income Measures Medical Records Mental Health Mexican Americans Morbidity - disease rate Mothers Neighborhoods Not Hispanic or Latino Obesity Overweight Parents Participant Pathway interactions Pattern Policies Poverty Prevention Preventive Process Protocols documentation Puberty Public Health Race Reporting Research Risk Risk Factors Sampling Shapes Stress Surveys System Time United States National Institutes of Health Weight Weight Gain World Health Organization Youth cardiometabolic risk cardiometabolism cardiovascular health coronavirus disease critical period cultural values ethnic minority ethnic minority population experience feeding health difference health disparity health equity health goals health inequalities high risk high risk population infancy longitudinal dataset middle childhood mortality obesity development obesity in children obesity prevention obesity risk pandemic disease physical conditioning prenatal prospective protective factors public health intervention racial population resilience resilience factor social social culture social group statistics stressor

项目摘要

Project Summary Substantial health inequities exist for Hispanic children. Recent national statistics indicate Hispanic youth are nearly twice as likely to be obese as non-Hispanic white youth. Cardiometabolic risk indicators are also elevated among Hispanic children relative to children of other ethnicities. The identification of risk and resiliency predictors of poor health during childhood and adolescence from a longitudinal and developmental perspective will provide specific targets amenable to preventive public health interventions. We propose to capitalize on longitudinal data collected by an NIH-funded study of very low-income Mexican American mothers and youth (Las Madres Nuevas) that assessed a multitude of cultural, biological, family, and environmental risk and protective factors from the prenatal period through ten years of age, including 13 objective measures of child weight and health beginning at birth. We propose to leverage this existing longitudinal dataset and evaluate weight gain and cardiometabolic health trajectories, and additional risk and resiliency factors at child ages 12-13 and 15-16. The COVID-19 pandemic and racial tensions in the U.S. provide natural ecological stressors that can disrupt normally-developing trajectories or worsen at-risk trajectories. With data collected recently on the impact of these stressors on youth, the project is ideally situated to examine health-related consequences of these significant social and environmental challenges. In combination, we will: 1) Examine trajectories of child weight gain from birth to age 15-16 years and associated cardiometabolic health consequences (e.g., blood pressure, HbA1c, cholesterol, CRP, IL-6); 2) Examine macro-level social, cultural, and environmental risk and protective factors (e.g., negative racial climate, concentrated disadvantage, neighborhood opportunity) that influence developmental trajectories in weight gain and cardiometabolic health. 3) Examine proximal influences (e.g., acculturation and cultural values; maternal and child mental health; family feeding and behavioral practices) on trajectories of weight gain and cardiometabolic health; 4) Conduct a nuanced examination of ecological and salient major life events (e.g., COVID, puberty) that potentially divert weight gain and cardiometabolic trajectories, focusing on the unique characteristics of youth who are relatively unaffected, recover, or are chronically affected. The proposed study utilizes data from biological measures, anthropometric measures, parent report, youth report, medical records, and observational protocols. Our scientific approach emphasizes the cultural embeddedness of healthy development, with the view that health equity can best be achieved by understanding sociocultural and economic forces that shape eating behavior and weight gain. This project holds great potential to address central questions about contributors to weight gain and obesity risk in a high-risk group, and enhance opportunities for prevention of obesity and associated health problems.

项目摘要西班牙裔儿童存在实质性健康不平等。最近的国家统计数据表明西班牙裔青年是肥胖的可能性几乎是非西班牙裔白人青年的两倍。心脏代谢风险指标也是相对于其他种族的孩子，西班牙裔儿童中的提升。识别风险和纵向和发育中儿童期和青春期健康状况不佳的弹性预测因素观点将为预防公共卫生干预措施提供特定目标。我们建议通过NIH资助的非常低收入的墨西哥裔美国人的研究收集的纵向数据评估了许多文化，生物学，家庭和从产前期到十岁的环境风险和保护因素，包括13个儿童体重和健康的客观度量从出生开始。我们建议利用这种现有的纵向数据集并评估体重增加和心脏代谢健康轨迹以及额外的风险和 12-13岁和15-16岁儿童的弹性因素。美国的19日大流行和种族紧张局势提供自然的生态压力源，可破坏正常发展的轨迹或处于危险中轨迹。由于最近收集了有关这些压力源对青年的影响的数据，因此理想情况下是该项目旨在检查这些重大社会和环境挑战的与健康相关的后果。在组合，我们将：1）检查从出生到15-16岁的儿童体重增加的轨迹以及相关的心脏代谢健康后果（例如血压，HBA1C，胆固醇，CRP，IL-6）； 2）检查宏观的社会，文化和环境风险和保护因素（例如，负面种族气候，集中劣势，邻里机会），影响体重增加的发展轨迹和心脏代谢健康。 3）检查近端影响（例如，适应和文化价值；孕产妇和儿童心理健康；家庭喂养和行为实践）关于体重增加的轨迹和心脏代谢健康； 4）对生态和显着的重大生活事件进行细微研究（例如， covid，青春相对不受影响，康复或长期影响的年轻人的特征。拟议的研究利用生物学措施，人体测量指标，家长报告，青年报告，病历，医疗记录，和观察方案。我们的科学方法强调了健康的文化嵌入发展，认为可以通过了解社会文化和塑造饮食行为和体重增加的经济力量。该项目具有巨大的潜力关于高风险群体体重增加和肥胖风险的贡献者的核心问题，并增强预防肥胖和相关健康问题的机会。

项目成果

期刊论文数量（21）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Infants' Biological Sensitivity to the Effects of Maternal Social Support: Evidence Among Mexican American Families.

DOI：
10.1111/infa.12266
发表时间：
2019-03
期刊：
Infancy : the official journal of the International Society on Infant Studies
影响因子：
0
作者：
Somers JA;Jewell SL;Hanna Ibrahim M;Luecken LJ
通讯作者：
Luecken LJ

Within-dyad bidirectional relations among maternal depressive symptoms and child behavior problems from infancy through preschool.

母亲抑郁症状与婴儿期至学前儿童行为问题之间的二元内双向关系。

DOI：
10.1017/s0954579421001656
发表时间：
2023
期刊：
Development and psychopathology
影响因子：
3.3
作者：
Curci,SarahG;Somers,JenniferA;Winstone,LauraK;Luecken,LindaJ
通讯作者：
Luecken,LindaJ

Association of BMI trajectories with cardiometabolic risk among low-income Mexican American children.

DOI：
10.1038/s41390-022-02250-1
发表时间：
2023-04
期刊：
PEDIATRIC RESEARCH
影响因子：
3.6
作者：
Perez, Marisol;Winstone, Laura K.;Hernandez, Juan C.;Curci, Sarah G.;McNeish, Daniel;Luecken, Linda J.
通讯作者：
Luecken, Linda J.

Quantifying the dynamic nature of vagal responsivity in infancy: Methodological innovations and theoretical implications.

DOI：
10.1002/dev.22018
发表时间：
2021-04
期刊：
Developmental psychobiology
影响因子：
2.2
作者：
Somers JA;Curci SG;Luecken LJ
通讯作者：
Luecken LJ

Discrimination and Depressive Symptoms Among Mexican American Women: Exploring Multilevel Sociocultural Moderators.

DOI：
10.1177/21677026221129628
发表时间：
2023-05
期刊：
CLINICAL PSYCHOLOGICAL SCIENCE
影响因子：
4.8
作者：
Curci, Sarah G.;Hernandez, Juan C.;Winstone, Laura K.;Perez, Marisol;Luecken, Linda J.
通讯作者：
Luecken, Linda J.