Pilot Projects Program

试点项目计划

• 批准号: 10684635
• 负责人: Curtis William Noonan
• 金额: $ 149.17万
• 依托单位: UNIVERSITY OF NEVADA LAS VEGAS
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-15 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10684635
• 关键词: Acceleration; Address; Award; Basic Science; Biometry; Centers of Research Excellence; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Communities; Community Outreach; Complex; Development; Extramural Activities; Faculty; Fostering; Funding; Funding Mechanisms; Goals; Grant; Health; Health Disparities Research; Infrastructure; Institution; Investments; Leadership; Mentors; Mentorship; Modeling; Multi-Institutional Clinical Trial; Network Infrastructure; Outcome; Patients; Pilot Projects; Population; Populations at Risk; Program Development; Research; Research Activity; Research Personnel; Resources; Site; Testing; Translational Research; Work; career; clinical research site; cohort; community engagement; experience; health disparity; innovation; multidisciplinary; pre-clinical; pre-clinical research; programs; success; support network

Summary The Clinical and Translational Infrastructure Network (CTR-IN) is a partnership of 13 institutions across 7 states to develop a culture of collaborative multidisciplinary clinical and translational health disparities research within and across western IDeA institutions to positively impact health in our communities. Support for CTR pilot projects is one of the key CTR-IN activities. The CTR-IN Pilot Projects Program (CP3, formerly known as CTPG [Clinical and Translational Pilot Grants]) has developed well-tested strategies for solicitation, merit review, and oversight of pilot grants. The success of CTR-IN pilot awardees is made possible through the close integration of CP3 funding for investigators with the biostatistical, mentorship and professional development support from the complementary CTR-IN Cores. To further grow the successful CP3, we have evolved our strategy to focus on health disparities research, and we have developed innovative strategies to support multisite collaborations and the building of multidisciplinary CTR teams. The CP3 funding strategies will enhance current CTR capacity in the region on several fronts. First, over the past 5 years a high proportion of investigators with CTR-IN pilot grant support have successfully obtained competitive extramural funding, yielding a positive return on investment that will continue to grow. We will continue to advance this objective by working in close collaboration with the new Community Engagement and Outreach (CEO) Core to identify populations at risk and health disparities of concern in our communities. Second, partnering across sites will build the necessary infrastructure to compete nationally for multisite clinical trials and related research. Our recent support of multisite collaborative pilot projects demonstrates both the demand for such projects among researchers and the proof of concept for initiating these more complex projects. Finally, supporting partnerships that bridge preclinical and clinical research will accelerate the delivery of solutions to patients and communities. Faculty at our partner institutions include a broad cohort of IDeA-supported basic science, preclinical investigators (e.g., INBRE, COBRE) and clinical investigators, yielding opportunities for building teams and leveraging core resources to advance research for greater benefit to patients and communities. Altogether, these strategies and anticipated outcomes will have an important impact on health in our communities.

概括 临床和转化基础设施网络（CTR-IN）是7个州的13个机构的合作伙伴关系 在内部发展协作多学科临床和转化健康差异研究的文化 以及整个西方思想机构，以积极影响我们社区的健康。支持CTR飞行员 项目是CTR-IN活动的关键活动之一。 CTR-IN试点项目计划（CP3，以前称为CTPG [临床和转化试点赠款]）已制定了经过良好测试的策略，以进行招标，优异审查和 监督飞行员赠款。通过紧密整合使CTR-IN飞行员获奖者的成功成为可能 为调查人员提供的CP3资金，并获得了生物统计学，指导和专业发展的支持 互补的CTR-IN内核。为了进一步发展成功的CP3，我们已经发展了我们的战略以集中精力 关于健康差异研究，我们制定了创新策略来支持多站点合作 以及跨学科CTR团队的建设。 CP3资金策略将增强当前的CTR容量 在几个方面的地区。首先，在过去的5年中 赠款支持已成功获得了竞争性校外资金，获得了积极的投资回报 那将继续增长。我们将通过与 新的社区参与和外展（CEO）核心，以确定处于风险和健康差异的人群 对我们社区的关注。其次，跨站点合作将建立必要的基础设施以竞争 全国用于多站点临床试验和相关研究。我们最近对多站点合作飞行员的支持 项目展示了研究人员中对此类项目的需求和概念证明 启动这些更复杂的项目。最后，支持桥梁和临床的伙伴关系 研究将加速向患者和社区提供解决方案。合作机构的教师 包括广泛的思想支持的基础科学，临床前研究者（例如inbre，cobre）和 临床研究人员，为建立团队提供了机会，并利用核心资源来推进 研究为患者和社区带来更大的利益。这些策略和预期的结果总共 将对我们社区的健康产生重要影响。