Core A: Administrative Core
核心A:行政核心
基本信息
- 批准号:10684102
- 负责人:
- 金额:$ 26.65万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-30 至 2027-08-31
- 项目状态:未结题
- 来源:
- 关键词:Acute Myelocytic LeukemiaAdministratorAgreementArchitectureBioinformaticsBiologyBiostatistics CoreBudgetsClinicalCollaborationsCommunicationCommunitiesComplexDataEnsureEnvironmentEvaluationEvolutionFosteringFundingGoalsGrantHemeIndividualIntellectual PropertyIntrinsic factorLaboratoriesLeadLeadershipNational Cancer InstituteOffice of Administrative ManagementOutcomePatientsPerformancePreparationProductivityProgress ReportsRecommendationReportingResearchResearch PersonnelResistanceResourcesScientific EvaluationScientistSpecimenSystemTechnologyTimeTranslational ResearchTravelWorkacquired drug resistancedata disseminationdata sharingexperienceinnovationleukemiameetingsnovel therapeutic interventionoperationpre-clinicalprogramstherapy resistanttimelinetumor
项目摘要
PROJECT SUMMARY/ABSTRACT: Administrative Core
The overall goal of our leukemia focused ARTNet Research Center is to understand how the architecture of
resistance is governed by temporal extrinsic and intrinsic factors in order to identify novel therapeutic strategies
to stay ahead of tumor evolution and adaptation in patients with Acute Myeloid Leukemia (AML). To achieve this
goal, we have assembled an exceptional team of leukemia researchers that bridge basic/mechanistic and
preclinical/translational research who have worked extensively together for 15+ years studying AML biology. The
Administrative Core will provide leadership, scientific oversight, governance, integration, and administrative
support to the ARTNet Research Center to ensure effective operations, communication, internal and external
collaborations, compliance, and rigorous scientific evaluation of ARTNet Consortium funded projects. The
Administrative Core co-Leads, Dr. Jeffrey Tyner (Contact M-PD/PI) and Dr. Cristina Tognon, have been working
together for close to a decade, and they have also both worked closely for this entire time with Administrative
Core Biostatistics and Bioinformatics Lead and Overall M-PD/PI, Dr. Shannon McWeeney. They will be
supported by a highly experienced Research and Finance Administrator, Sarah Bowden. The specific aims of
the Administrative Core are to: 1) Provide overall administrative management by providing governance and
scientific integration of the Center and developing and implementing a staffing plan; 2) Create an environment
that fosters a focused and synergistic relationship between the Projects and the Cores; 3) Provide ARTNet
Research Center compliance oversight and evaluate scientific progress; and 4) Enable rapid dissemination of
data and resources. To achieve these aims, the Administrative Core will establish and implement ARTNet
Research Center governance, including establishing a Scientific Advisory Board (SAB) to help evaluate the
Center’s progress toward its aims and milestones; plan regular strategic interactions and meetings; develop
communication plans; ensure budget oversight and compliance; manage intellectual property issues; complete
annual progress reports; facilitate regular and timely communication; facilitate collaboration within the Center
and with external collaborations; and perform all other administrative duties required to support the ARTNet
Research Center and its successful participation in the Acquired Resistance to Therapy Network.
项目摘要/摘要:行政核心
我们专注于白血病的 ARTNet 研究中心的总体目标是了解
耐药性受时间外在和内在因素控制,以便确定新的治疗策略
领先于急性髓系白血病 (AML) 患者的肿瘤进化和适应。
为了实现这个目标,我们组建了一支由白血病研究人员组成的杰出团队,将基础/机械和
临床前/转化研究人员主要一起工作了 15 年以上,研究 AML 生物学。
行政核心将提供领导、科学监督、治理、整合和行政管理
支持ARTNet研究中心,确保内部和外部的有效运营、沟通
ARTNet 联盟资助项目的合作、合规性和严格的科学评估。
行政核心联合负责人 Jeffrey Tyner 博士(联系人 M-PD/PI)和 Cristina Tognon 博士一直在工作
他们一起工作了近十年,并且在整个时间里他们都与行政部门密切合作
Shannon McWeeney 博士是核心生物统计学和生物信息学主管和总体 M-PD/PI。
由经验丰富的研究和财务管理员 Sarah Bowden 提供支持。
行政核心是: 1) 通过提供治理和
中心科学整合,制定并实施人员配置计划; 2)营造环境;
3)提供ARTNet
研究中心合规性监督和评估科学进展;以及 4) 实现快速传播
为了实现这些目标,管理核心将建立并实施 ARTNet。
研究中心治理,包括建立科学顾问委员会(SAB)来帮助评估
中心实现其目标和里程碑的进展;规划定期的战略互动和会议;
沟通计划;确保预算监督和合规性;管理知识产权问题;
年度进展报告;促进定期和及时的沟通;促进中心内部的合作;
以及与外部合作;并履行支持 ARTNet 所需的所有其他管理职责
研究中心及其成功参与获得性治疗耐药网络。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jeffrey Wallace Tyner其他文献
Jeffrey Wallace Tyner的其他文献
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{{ truncateString('Jeffrey Wallace Tyner', 18)}}的其他基金
Trajectory and Architecture of Tumor Intrinsic Drug Resistance in AML
AML 肿瘤内在耐药性的轨迹和结构
- 批准号:
10684105 - 财政年份:2017
- 资助金额:
$ 26.65万 - 项目类别:
Trajectory and Architecture of Tumor Intrinsic Drug Resistance in AML
AML 肿瘤内在耐药性的轨迹和结构
- 批准号:
10517760 - 财政年份:2017
- 资助金额:
$ 26.65万 - 项目类别:
Drug Combinations to Enhance Sensitivity and Circumvent Resistance
增强敏感性和规避耐药性的药物组合
- 批准号:
10249170 - 财政年份:2017
- 资助金额:
$ 26.65万 - 项目类别:
Drug Combinations to Enhance Sensitivity and Circumvent Resistance
增强敏感性和规避耐药性的药物组合
- 批准号:
9985235 - 财政年份:2017
- 资助金额:
$ 26.65万 - 项目类别:
Drug Combinations to Enhance Sensitivity and Circumvent Resistance
增强敏感性和规避耐药性的药物组合
- 批准号:
9444902 - 财政年份:2017
- 资助金额:
$ 26.65万 - 项目类别:
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