Pilot/Exploratory Studies Core (PESC)

试点/探索性研究核心（PESC）

• 批准号: 10670210
• 负责人: Mary McGrae McDermott
• 金额: $ 29.52万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670210
• 关键词: Accident and Emergency department; Advisory Committees; Aging; American; Applications Grants; Applied Research; Award; Back; Capsicum; Caregivers; Caring; Chicago; Clinical; Clinical Sciences; Communication; Communities; Complex; Data; Depressed mood; Development; Direct Costs; Elderly; Electronics; Emergency Care; Emergency Medicine; Faculty; Foundations; Funding; Future; Geriatrics; Goals; Grant; Health; Industry; Information Dissemination; Institution; Intervention; Lead; Leadership; Life Cycle Stages; Link; Managed Care; Manuscripts; Measurement; Medical; Medication Errors; Mental Depression; Mentors; Methodology; Modeling; Monitor; Patients; Peer Review; Pharmaceutical Preparations; Pharmacotherapy; Pilot Projects; Primary Care; Process; Publishing; Quality of life; Readiness; Recommendation; Request for Applications; Research; Research Design; Research Personnel; Research Project Grants; Resources; Services; Skilled Nursing Facilities; Stream; Study Section; System; Training; Translational Research; United States National Institutes of Health; Universities; Voice; Work; career; community involvement; design; education research; expectation; experience; faculty support; functional improvement; functional outcomes; hospital readmission; improved; innovation; intelligent personal assistant; interest; meetings; member; multidisciplinary; multiple chronic conditions; novel; pilot test; primary care practice; primary care services; professor; programs; psychologic; tool

ABSTRACT The overarching goal of the Northwestern Older Americans Independence Center (OAIC, a.k.a. `Pepper Center') is to generate innovative research to enhance primary care for medically complex, older adults with multiple chronic conditions (MCC) to achieve optimal health, independence, and quality of life. The Pilot/Exploratory Studies Core (PESC) will be strategically linked to the Research Education Component (REC), to i) identify, select, and fund junior faculty, `Pepper Scholar' trainees with aging interests related to MCC; ii) mentor, support and monitor Scholars through a formidable research project that will provide them with sufficient preliminary data to help justify larger, independent grant proposals and successfully advance their career. The specific aims of the PESC are to: Aim 1 Fund, initiate, and conduct a first wave of Pilot/Exploratory Studies (PES 1-3) that will engage junior investigators in Northwestern's OAIC research enterprise and generate innovative research designed to improve function and quality of life for older Americans with MCC. Aim 2 Implement a process by which the Northwestern OAIC will solicit, peer-review, select and prioritize, support, and monitor at least 9 PES in the first 5 years of the Northwestern OAIC. Aim 3 Encourage the development of competitive, external grant applications leveraging Pepper Scholar PES and others doing related work at Northwestern, in Chicago and throughout the OAIC Network. Our Northwestern OAIC will award three waves of PES funding in Years 1-3 (minimum 9 awards, at least 3 per year); Center leadership held a competitive solicitation for pilot projects and have identified the 1st wave of Pepper Scholar PES: 1) Improving Transitions of Care from Skilled Nursing Facilities to the Community (Dr. Theresa Rowe, Assistant Professor, Geriatrics); 2) Intelligent Personal Assistant Depression Management for Homebound Older Adults ((Dr. Katherine O'Brien, Assistant Professor, Geriatrics); 3) An Emergency Department -based Deprescribing Intervention for Older Adults with MCC (Dr. Howard Kim, Assistant Professor, Emergency Medicine). The PESC will leverage processes and systems developed by the Northwestern University Clinical and Translational Sciences Institute (NUCATS) to manage PES competitions in Years 2 and 3; projects receive up to $100,000 direct costs over 2 years with in-kind methodological support from our OAIC Resource Cores (Design, Measurement, Analytics). Our trainee `pipeline' now extends to other academic institutions (UIC, Rush). Our Information Dissemination Core will also aid Pepper Scholars in widely disseminating PES findings.

抽象的 西北美国人独立的总体目标 中心（OAIC，又名“胡椒中心”）是为了产生创新的研究 增强医学复杂的，多个慢性的老年人的初级保健 条件（MCC）实现最佳健康，独立性和生活质量。 试点/探索性研究核心（PESC）将在战略上与 研究教育部分（REC），i）确定，选择和资助初级 教师，“胡椒学者”学员，与MCC有关的老龄化兴趣； ii）导师， 通过强大的研究项目支持和监视学者 向他们提供足够的初步数据，以帮助证明更大，独立的合理 提出建议，并成功地发展了他们的职业生涯。 PESC的具体目的是： AIM 1基金，启动和进行第一波试点/探索性研究（PES 1-3），该研究将吸引初级 西北OAIC研究企业的研究人员并生成创新研究设计 改善MCC老年人的生活和生活质量。 AIM 2实施一个过程，西北OAIC将通过该过程征求，同行评审，选择和优先级， 支持，并在OAIC西北部的头5年中至少监测9 PE。 AIM 3鼓励开发竞争性的外部赠款应用程序利用Pepper Scholar PES和其他人在西北，芝加哥和整个OAIC网络中从事相关工作。 我们的西北OAIC将在1 - 3年内授予三波PES资金（至少9个奖项，至少3个） 年）;中心领导对飞行员项目进行了竞争招标，并确定了第一波胡椒 学者PES：1）改善从熟练护理设施向社区的护理过渡（Theresa博士 Rowe，老年医学助理教授）； 2）智能个人助理抑郁管理 家里老年人（（（凯瑟琳·奥布莱恩博士，老年医学助理教授）； 3）急诊科 - 基于MCC的老年人基于对老年人的划分干预（霍华德·金博士，紧急助理教授助理教授 药品）。 PESC将利用西北大学临床开发的过程和系统 和转化科学研究所（NUCATS）在2年和3年内管理PES竞争；项目收到 在我们的OAIC资源核心中，多达2年内的直接成本高达100,000美元的直接费用 （设计，测量，分析）。我们的实习生“管道”现在扩展到其他学术机构（UIC，Rush）。 我们的信息传播核心还将有助于胡椒学者广泛传播PES的发现。