Mentoring Patient-Oriented Research to Prevent Injury in Older Adults

指导以患者为导向的研究以防止老年人受伤

• 批准号: 10532744
• 负责人: Sarah Dyer Berry
• 金额: $ 12.08万
• 依托单位: HEBREW REHABILITATION CENTER FOR AGED
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-15 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10532744
• 关键词: Accidental Injury; Advisory Committees; Aging; Alzheimer' s disease patient; Alzheimer' s disease related dementia; American; Anticoagulants; Antihypertensive Agents; Award; Benefits and Risks; Caring; Cause of Death; Characteristics; Clinical; Clinical Investigator; Clinical Trials; Collaborations; Competence; Data; Development; Discipline; Dislocations; Elderly; Emergency department visit; Exercise; Feedback; Fellowship; Fracture; Funding; Future; Genetic; Geriatrics; Goals; Grant; Health; Healthcare; Hip Fractures; Hospitalization; Hypoglycemic Agents; Ingestion; Injury; Institute of Medicine (U.S.); Intervention; Intracranial Hemorrhages; Investigation; K-Series Research Career Programs; Lead; Leadership; Link; Literature; Medical; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Multi-Institutional Clinical Trial; Nursing Homes; Observational Study; Operative Surgical Procedures; Osteoporosis; Overdose; Patients; Performance; Persons; Pharmaceutical Preparations; Physicians; Physiological; Reading; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Resources; Risk Factors; Role; Scientific Inquiry; Scientist; Specialist; Surgical complication; Syndrome; Testing; Testosterone; Time; Training; Training Programs; Translational Research; Work; age related; attributable mortality; burnout; career; design; experience; fall injury; falls; feasibility trial; health care service utilization; implementation science; improved; interest; investigator training; large datasets; medical schools; modifiable risk; neglect; novel; older patient; older women; patient oriented; patient oriented research; prevent; programs; shared decision making; skills; success; trend; vehicular accident; Accidental Injury; Advisory Committees; Aging; Alzheimer' s disease patient; Alzheimer' s disease related dementia; American; Anticoagulants; Antihypertensive Agents; Award; Benefits and Risks; Caring; Cause of Death; Characteristics; Clinical; Clinical Investigator; Clinical Trials; Collaborations; Competence; Data; Development; Discipline; Dislocations; Elderly; Emergency department visit; Exercise; Feedback; Fellowship; Fracture; Funding; Future; Genetic; Geriatrics; Goals; Grant; Health; Healthcare; Hip Fractures; Hospitalization; Hypoglycemic Agents; Ingestion; Injury; Institute of Medicine (U.S.); Intervention; Intracranial Hemorrhages; Investigation; K-Series Research Career Programs; Lead; Leadership; Link; Literature; Medical; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Multi-Institutional Clinical Trial; Nursing Homes; Observational Study; Operative Surgical Procedures; Osteoporosis; Overdose; Patients; Performance; Persons; Pharmaceutical Preparations; Physicians; Physiological; Reading; Reporting; Research; Research Personnel; Research Project Grants; Research Training; Resources; Risk Factors; Role; Scientific Inquiry; Scientist; Specialist; Surgical complication; Syndrome; Testing; Testosterone; Time; Training; Training Programs; Translational Research; Work; age related; attributable mortality; burnout; career; design; experience; fall injury; falls; feasibility trial; health care service utilization; implementation science; improved; interest; investigator training; large datasets; medical schools; modifiable risk; neglect; novel; older patient; older women; patient oriented; patient oriented research; prevent; programs; shared decision making; skills; success; trend; vehicular accident

There is a real shortage of clinicians trained in geriatric principles, with even fewer clinicians with geriatric competencies also trained in patient-oriented research. My overarching goal is to grow the field of young investigators properly trained in patient-oriented aging research, and to improve the health of frail, older adults through my research efforts focused on unintentional injury. For more than ten years I have had funding from the NIA to study injurious falls in frail, older adults, and for the past six years I have served as the Program Director for the Harvard Multicampus Geriatric Medicine Fellowship. The current proposal will capitalize on my strengths as an independent clinical investigator with expertise in injurious falls and program leader to enhance my capacity to mentor early investigators in aging research. The specific aims of the current proposal are to 1) conduct high-quality research on preventing unintentional injuries in frail, older adults that will serve as a platform to engage early investigators in patient-oriented aging research; 2) grow the number of well-trained investigators skilled in studying unintentional injury in older adults; and 3) enhance my skills to lead and mentor early clinical investigators by completing formal didactic training focused on implementation science and leadership. Ongoing funded research projects that could serve as a platform to engage research trainees include a large observational study to determine the risks and benefits of antihypertensive, antihyperglycemic, and anticoagulant drugs in older adults with Alzheimer’s Disease and Related Dementias (ADRD), as well as a feasibility trial to develop and implement an intervention to prevent injurious falls in older nursing home residents. Additionally I have conducted research and continue to collaborate with investigators using several large datasets that will serve as an excellent resource for trainees. Potential mentees will be identified from a pipeline of existing training programs at Harvard Medical School including the Geriatric Medicine Fellowship, Translational Research in Aging Programs (T32), and others. I will develop an individualized mentoring plan with all trainees, including the design of an original hypothesis-driven research project, plan for individualized and group mentorship, and opportunities for coursework/didactics to enhance research training. Finally, I will boost my own mentoring skills through 1) formal didactics and directed reading on implementation science; 2) directed reading/coursework on mentorship; 3) a leadership course; 4) a course on preventing burnout; and 5) additional coursework (e.g., introduction to genetics) to expand my scientific inquiry. A Senior Advisory panel will provide feedback on my performance as a mentor and leader. In summary, this Career Development Award will provide me with the practical experience and formal didactic training to expand my capacity as a researcher, leader, and mentor in patient-oriented research on unintentional injury, including patients with ADRD. At the end of this 5-year award, I will have equipped at least 18 early investigators in the study of unintentional injury, many of whom will enter the field of aging research.

实际缺乏接受老年原则培训的临床医生，而老年医生的临床医生更少 还接受了以患者为导向的研究培训的能力。我的总体目标是发展年轻的领域 在以患者为导向的衰老研究中对研究人员进行了适当的培训，并改善了脆弱的老年人的健康 通过我的研究工作，集中于无意伤害。十多年来，我从 NIA研究脆弱的老年人有害跌倒的NIA，在过去的六年中，我一直担任该计划 哈佛多学院老年医学奖学金主任。当前的提议将利用我的 作为一名独立临床研究者的优势，在意外跌倒和计划负责人方面具有专业知识来增强 我在衰老研究中进行心理早期研究人员的能力。当前建议的具体目的是1） 对预防脆弱的老年人无意损伤进行高质量研究，这将作为 使早期研究人员参与以患者为导向的衰老研究的平台； 2）增加训练有素的数量 熟练研究老年人无意损伤的研究人员； 3）提高我领导和指导的技能 早期的临床研究人员通过完成专注于实施科学的正式教学培训和 领导。正在进行的资助的研究项目，可以作为吸引研究受训者的平台 包括一项大型观察性研究，以确定降压，抗血糖的风险和益处， 老年人患有阿尔茨海默氏病和相关痴呆症（ADRD）的老年人的抗凝药物以及 可行性试验，以制定和实施干预措施，以防止老年护士之家有害 居民。此外，我进行了研究，并继续与调查员合作使用几个 大型数据集将是培训的绝佳资源。潜在的受训者将从 哈佛医学院现有培训计划的管道，包括老年医学奖学金， 老化计划的转化研究（T32）等。我将制定一个个性化的心理计划 与所有学员一起，包括设计原始假设驱动的研究项目的设计， 以及小组心态，以及课程/教学的机会，以增强研究培训。最后，我会的 通过1）正式的教学和实施科学的读物来提高我自己的心理技能； 2） 指导有关Mentalship的阅读/课程； 3）领导课程； 4）关于防止倦怠的课程； 5） 其他课程（例如遗传学简介）扩大了我的科学询问。高级咨询小组 将提供有关我作为心理和领导者表现的反馈。总而言之，这一职业发展 奖项将为我提供实用的经验和正式的教学培训，以扩大我的能力 研究人员，领导者和心理意识到无意间损伤的研究，包括患者 adrd。在这项5年奖励结束时，我将在研究中至少有18位早期调查人员 无意的伤害，其中许多人将进入衰老研究领域。