Research and Methods Core

研究和方法核心

• 批准号: 10661439
• 负责人: JUSTIN D SMITH
• 金额: $ 27.55万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-03 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661439
• 关键词: Address; Adoption; Advanced Malignant Neoplasm; Area; Behavior; Biometry; Cancer Control; Cancer Prevention Intervention; Child; Collaborations; Common Data Element; Community Services; Ensure; Environmental Exposure; Equity; Evidence based intervention; Family; Fostering; Goals; Health; Individual; Inequity; Infrastructure; Intervention; Knowledge; Leadership; Logic; Malignant Neoplasms; Measurement; Measures; Methodology; Methods; Modeling; Modification; Outcome; Persons; Pilot Projects; Policies; Population; Poverty; Poverty Areas; Prevention; Prevention program; Productivity; Reproducibility; Research; Research Activity; Research Design; Research Methodology; Research Project Grants; Research Project Summaries; Research Support; Resources; Science; Specific qualifier value; Structure; System; Techniques; Time; Training; Translational Research; Underserved Population; United States National Institutes of Health; Work; Youth; cancer prevention; career; community engagement; data sharing; economic evaluation; evaluation/testing; evidence base; experience; health care service; health economics; health equity; implementation evaluation; implementation facilitation; implementation outcomes; implementation process; implementation research; implementation science; implementation strategy; improved; individualized prevention; innovation; mortality disparity; novel; prevent; scale up; synergism; tool

RESEARCH AND METHODS CORE: PROJECT SUMMARY The Research and Methods Core (RMC) will drive the application of innovative methodologic solutions to the challenges of implementing evidence-based interventions for the prevention of cancer among people living in persistent poverty. The central goal is achieving reach through equitable implementation to meet the needs and resources of delivery systems that serve youth, families, and individuals in areas of persistent poverty. The RMC will support the research activities of “HOPE & CAIRHE 2gether” (HC2) through three specific aims: Aim 1: INNOVATE: Serve as a hub for cross-project methodologic synergies to advance cancer prevention implementation science in persistent poverty areas. The RMC will ensure proper application of novel implementation research tools while highlighting unique methodologic advancements facilitated by HC2's collaborative structure. Central to this aim are innovations facilitated by three methods developed by RMC Co- Lead Smith: (1) the Implementation Research Logic Model; (2) an implementation outcomes common data elements tool; and (3) a novel and rigorous system for longitudinal tracking of implementation strategies and their dynamic modifications over time. Aim 2: SUPPORT: Ensure methodologic support for HC2 research activities. The RMC will ensure that HC2's Research and Pilot Projects have excellent methodologic support to carry out their specific aims and those of HC2 overall. Specifically, the RMC will identify common data elements, orchestrate the use of shared measures, and provide rigorous quantitative, qualitative, health economic analyses and implementation science methods across the Research and Pilot Projects. We will use quantitative, qualitative, and mixed methods approaches to answer each project's stated specific aims as well as novel and convergent research questions that emerge through HC2's work. Aim 3: EVALUATE: Measure HC2 research productivity and impact. The RMC will collaborate with the Administrative Core to measure and evaluate HC2's progress toward achieving research and training milestones and outcomes. We will use the Translational Science Benefits Model to demonstrate the impact of our work in the real world on metrics salient to HC2 and the Persistent Poverty Initiative (RFA-CA-22-015). The RMC is Co-Led by experts with complementary expertise in prevention implementation science methods, research design, and quantitative, qualitative, and mixed methods analysis. Four workgroups will carry out RMC's aims: (1) Implementation Evaluation & Measurement; (2) Biostatistics & Research Design; (3) Qualitative & Mixed Methods; and (4) Health Economics. RMC will coordinate with the Administrative Core, Career Enhancement Core, and Community Engagement Team to ensure methodologic support and rigor across HC2 activities. RMC's contributions will generate critical methodologic advances towards reducing the cancer mortality disparities experienced by individuals living in persistent poverty.

研究与方法核心：项目摘要 研究和方法核心（RMC）将推动创新方法论解决方案的应用 实施基于证据的干预措施以预防生活的人的癌症的挑战 在持续的贫困中。中心目标是通过公平实施实现触及的目标以满足需求 以及在持续贫困地区为青年，家庭和个人服务的交付系统的资源。这 RMC将通过三个特定目标来支持“ Hope＆Cairhe 2Gether”（HC2）的研究活动： 目标1：创新：作为跨项目的枢纽，以预防预防癌症 持续贫困地区的实施科学。 RMC将确保适当应用新颖 实施研究工具同时突出了HC2的独特方法论 协作结构。此目标的核心是通过RMC共同开发的三种方法制定的创新 史密斯铅：（1）实施研究逻辑模型； （2）实施结果共同数据 元素工具； （3）一种新颖而严格的系统，用于纵向跟踪实施策略和 随着时间的流逝，他们的动态修改。目标2：支持：确保对HC2研究的方法学支持 活动。 RMC将确保HC2的研究和试点项目具有出色的方法论支持 实现他们的特定目标以及总体上的HC2目标。具体而言，RMC将识别常见数据 元素，协调共享测量的使用，并提供严格的定量，定性，健康 经济分析和实施科学方法在整个研究和试点项目中。我们将使用 定量，定性和混合方法的方法来回答每个项目的特定目的以及 通过HC2的工作出现的新颖和收敛的研究问题。目标3：评估：测量HC2 研究生产力和影响。 RMC将与行政核心合作以衡量和 评估HC2在实现研究和培训里程碑和结果方面的进步。我们将使用 转化科学福利模型，以证明我们的工作在现实世界中的影响对指标 对HC2的重要性和持续的贫困计划（RFA-CA-22-015）。 RMC由具有预防实施科学专业知识的专家专家共同领导 方法，研究设计和定量，定性和混合方法分析。四个工作组将 执行RMC的目标：（1）实施评估和测量； （2）生物统计学和研究设计； （3） 定性和混合方法； （4）健康经济学。 RMC将与行政核心协调， 职业增强核心和社区参与团队，以确保方法论支持和严格 跨HC2活动。 RMC的贡献将产生关键的方法论，以减少 生活在持续贫困中的个人经历的癌症死亡率分布。