Research and Methods Core

研究和方法核心

• 批准号: 10661439
• 负责人: JUSTIN D SMITH
• 金额: $ 27.55万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-03 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661439
• 关键词: Address; Adoption; Advanced Malignant Neoplasm; Area; Behavior; Biometry; Cancer Control; Cancer Prevention Intervention; Child; Collaborations; Common Data Element; Community Services; Ensure; Environmental Exposure; Equity; Evidence based intervention; Family; Fostering; Goals; Health; Individual; Inequity; Infrastructure; Intervention; Knowledge; Leadership; Logic; Malignant Neoplasms; Measurement; Measures; Methodology; Methods; Modeling; Modification; Outcome; Persons; Pilot Projects; Policies; Population; Poverty; Poverty Areas; Prevention; Prevention program; Productivity; Reproducibility; Research; Research Activity; Research Design; Research Methodology; Research Project Grants; Research Project Summaries; Research Support; Resources; Science; Specific qualifier value; Structure; System; Techniques; Time; Training; Translational Research; Underserved Population; United States National Institutes of Health; Work; Youth; cancer prevention; career; community engagement; data sharing; economic evaluation; evaluation/testing; evidence base; experience; health care service; health economics; health equity; implementation evaluation; implementation facilitation; implementation outcomes; implementation process; implementation research; implementation science; implementation strategy; improved; individualized prevention; innovation; mortality disparity; novel; prevent; scale up; synergism; tool

RESEARCH AND METHODS CORE: PROJECT SUMMARY The Research and Methods Core (RMC) will drive the application of innovative methodologic solutions to the challenges of implementing evidence-based interventions for the prevention of cancer among people living in persistent poverty. The central goal is achieving reach through equitable implementation to meet the needs and resources of delivery systems that serve youth, families, and individuals in areas of persistent poverty. The RMC will support the research activities of “HOPE & CAIRHE 2gether” (HC2) through three specific aims: Aim 1: INNOVATE: Serve as a hub for cross-project methodologic synergies to advance cancer prevention implementation science in persistent poverty areas. The RMC will ensure proper application of novel implementation research tools while highlighting unique methodologic advancements facilitated by HC2's collaborative structure. Central to this aim are innovations facilitated by three methods developed by RMC Co- Lead Smith: (1) the Implementation Research Logic Model; (2) an implementation outcomes common data elements tool; and (3) a novel and rigorous system for longitudinal tracking of implementation strategies and their dynamic modifications over time. Aim 2: SUPPORT: Ensure methodologic support for HC2 research activities. The RMC will ensure that HC2's Research and Pilot Projects have excellent methodologic support to carry out their specific aims and those of HC2 overall. Specifically, the RMC will identify common data elements, orchestrate the use of shared measures, and provide rigorous quantitative, qualitative, health economic analyses and implementation science methods across the Research and Pilot Projects. We will use quantitative, qualitative, and mixed methods approaches to answer each project's stated specific aims as well as novel and convergent research questions that emerge through HC2's work. Aim 3: EVALUATE: Measure HC2 research productivity and impact. The RMC will collaborate with the Administrative Core to measure and evaluate HC2's progress toward achieving research and training milestones and outcomes. We will use the Translational Science Benefits Model to demonstrate the impact of our work in the real world on metrics salient to HC2 and the Persistent Poverty Initiative (RFA-CA-22-015). The RMC is Co-Led by experts with complementary expertise in prevention implementation science methods, research design, and quantitative, qualitative, and mixed methods analysis. Four workgroups will carry out RMC's aims: (1) Implementation Evaluation & Measurement; (2) Biostatistics & Research Design; (3) Qualitative & Mixed Methods; and (4) Health Economics. RMC will coordinate with the Administrative Core, Career Enhancement Core, and Community Engagement Team to ensure methodologic support and rigor across HC2 activities. RMC's contributions will generate critical methodologic advances towards reducing the cancer mortality disparities experienced by individuals living in persistent poverty.

研究和方法核心：项目摘要 研究和方法核心（RMC）将推动创新方法解决方案的应用 实施循证干预措施预防癌症的挑战 中心目标是通过公平实施来满足需求。 以及为持续贫困地区的青年、家庭和个人提供服务的交付系统资源。 RMC 将通过三个具体目标支持“HOPE & CAIRHE 2gether”（HC2）的研究活动： 目标 1：创新：充当跨项目方法协同作用的中心，以推进癌症预防 RMC 将确保新方法在持续贫困地区的科学实施。 实施研究工具，同时强调 HC2 促进的独特方法进步 这一目标的核心是 RMC Co- 开发的三种方法所促进的创新。 Lead Smith：（1）实施研究逻辑模型；（2）实施结果通用数据 要素工具；(3) 一个新颖且严格的系统，用于纵向跟踪实施策略和 目标 2：支持：确保 HC2 研究的方法学支持。 RMC 将确保 HC2 的研究和试点项目拥有出色的方法支持。 具体来说，RMC 将确定通用数据。 要素，协调使用共享措施，并提供严格的定量、定性、健康 我们将在研究和试点项目中使用经济分析实施和科学方法。 定量、定性和混合方法来回答每个项目规定的具体目标以及 HC2 工作中出现的新颖且趋同的研究问题 目标 3：评估：测量 HC2。 RMC 将与行政核心合作衡量和影响。 评估 HC2 在实现研究和培训里程碑和成果方面的进展。 转化科学效益模型展示了我们在现实世界中的工作对指标的影响 HC2 和持续贫困倡议 (RFA-CA-22-015) 的重点。 RMC 由在预防实施科学方面具有互补专业知识的专家共同领导 方法、研究设计以及定量、定性和混合方法分析。 实现 RMC 的目标：(1) 实施评估和测量；(2) 生物统计和研究设计；(3) 定性和混合方法；(4) 卫生经济学将与行政核心协调， 职业提升核心和社区参与团队，确保方法支持和严谨性 RMC 的贡献将为减少 HC2 活动带来关键的方法进步。 生活在持续贫困中的个人所经历的癌症死亡率差异。