The Upstream Center: Income Interventions to Address the Fundamental Causes of Cancer Inequities

上游中心：解决癌症不平等根本原因的收入干预措施

• 批准号: 10661407
• 负责人: MELISSA L. BONDY
• 金额: $ 209.5万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-26 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661407
• 关键词: Address; Advanced Malignant Neoplasm; Affect; Area; Behavior; Behavioral; California; Cancer Burden; Cancer Control; Cancer Etiology; Cancer Science; Cancer health equity; Catchment Area; Cause of Death; Cessation of life; Collaborations; Communities; Complex; Data Scientist; Development; Diet; Environment; Food; Foundations; Health; Health Services Accessibility; Health behavior; Health system; Healthcare; Housing; Incidence; Income; Income Tax; Individual; Inequity; Intervention; Learning; Low income; Malignant Neoplasms; Mediating; Methodology; Outcome; Personal Satisfaction; Persons; Physical activity; Pilot Projects; Play; Policies; Policy Developments; Policy Maker; Population; Poverty; Poverty Areas; Process; Research; Research Personnel; Research Project Grants; Resources; Risk Factors; San Francisco; Science; Social Change; Social Sciences; Social Work; Supplementation; Testing; Training; Transportation; Universities; Wages; Work; cancer prevention; cancer risk; career; career development; deprivation; economic disparity; evidence base; improved; innovation; mathematical model; member; mortality; novel; poor communities; prevent; programs; research and development; screening; social; social determinants; social disparities; social health determinants; stress reduction; structural determinants; Address; Advanced Malignant Neoplasm; Affect; Area; Behavior; Behavioral; California; Cancer Burden; Cancer Control; Cancer Etiology; Cancer Science; Cancer health equity; Catchment Area; Cause of Death; Cessation of life; Collaborations; Communities; Complex; Data Scientist; Development; Diet; Environment; Food; Foundations; Health; Health Services Accessibility; Health behavior; Health system; Healthcare; Housing; Incidence; Income; Income Tax; Individual; Inequity; Intervention; Learning; Low income; Malignant Neoplasms; Mediating; Methodology; Outcome; Personal Satisfaction; Persons; Physical activity; Pilot Projects; Play; Policies; Policy Developments; Policy Maker; Population; Poverty; Poverty Areas; Process; Research; Research Personnel; Research Project Grants; Resources; Risk Factors; San Francisco; Science; Social Change; Social Sciences; Social Work; Supplementation; Testing; Training; Transportation; Universities; Wages; Work; cancer prevention; cancer risk; career; career development; deprivation; economic disparity; evidence base; improved; innovation; mathematical model; member; mortality; novel; poor communities; prevent; programs; research and development; screening; social; social determinants; social disparities; social health determinants; stress reduction; structural determinants

Overall Component: Project Summary/Abstract Persistent poverty environments impose particular challenges for cancer prevention, with complex and intersecting factors creating barriers at the individual, health system, and population level. Improving cancer outcomes in these areas requires transformational, multisector solutions targeting fundamental causes and social determinants of health, with research and policy development processes that are co-created with the impacted communities. To address this challenge, we will form the UPSTREAM Research Center, an innovative approach to the fundamental problem of income deprivation by leveraging state programs for Guaranteed Basic Income and the Earned Income Tax Credit (EITC). Our team science approach to this problem is supported by the unparalleled resources at Stanford University, the University of California, San Francisco and the University of California, Davis. Our work advances multiple conceptual and methodological innovations through two main research projects: 1) an ongoing partnership with the California Department of Social Services to access and evaluate a $35M intervention of Guaranteed Basic Income in persistent poverty areas with a focus on modifiable cancer risk factors and intermediate outcomes; 2) the impact of increases in income support through the EITC, which in California has a unique focus on lower income wage earners, as well as undocumented workers. Our Specific Aims are to: Aim 1. Build a collaborative community of residents in persistent poverty areas, policy makers, trainees, cancer and social science researchers and data scientists that co-create programs to address the fundamental impacts of income deprivation, Aim 2. Evaluate the impact of income-based interventions in demographically diverse persistent poverty areas in Northern CA, Aim 3. Develop a mathematical model, with community input, that can assist in predicting long-term impacts of income-focused interventions on cancer incidence, providing community members, policy makers, and researchers with guidance on how best to eliminate the increased burden of cancer in persistent poverty areas, Aim 4. Develop and implement a career enhancement program that will facilitate the training and career development of a diverse cadre of interdisciplinary early-career scholars who are committed to advancing cancer health equity through research and practice in persistent poverty areas, and Aim 5. Implement innovative and collaborative cancer prevention and control programs identified through the UPSTREAM Research Center research projects and our community partners to develop long-term sustainable strategies in our Northern CA Catchment Areas and across the Persistent Poverty Centers Network. Results from this novel groundbreaking work will lay the foundation for transformative approaches to address cancer prevention and control programs in the face of severe economic and social disadvantage through capacity building and sustainable partnerships with policymakers, state and local agencies and community partners.

总体组件：项目摘要/摘要 持续的贫困环境对预防癌症构成了特殊的挑战，复杂和 相交的因素在个人，卫生系统和人口水平上造成障碍。改善癌症 这些领域的成果需要针对基本原因的转型，多部门解决方案 健康的社会决定因素，以及与之共同创建的研究和政策制定过程 受影响的社区。为了应对这一挑战，我们将组成上游研究中心 通过利用国家计划来解决基本收入剥夺问题的创新方法 保证基本收入和所赚取的所得税信用（EITC）。我们的团队科学方法 问题得到了斯坦福大学，加利福尼亚大学SAN的无与伦比的资源 弗朗西斯科和加利福尼亚大学戴维斯分校。我们的工作推进了多种概念和方法论 通过两个主要研究项目的创新：1）与加利福尼亚部门的持续合作 访问和评估3500万美元的保证基本收入的社会服务持续贫困 专注于可修改的癌症危险因素和中间结果的领域； 2）增加的影响 通过EITC的收入支持，在加利福尼亚州，该公司对低收入工资的独特关注， 以及无证件工人。我们的具体目的是：AIM 1。建立一个由居民组成的协作社区 在持续的贫困地区，政策制定者，学员，癌症和社会科学研究人员和数据科学家 该计划是为了解决收入剥夺的基本影响的计划，目标2。评估 基于收入的干预措施对北部北部人口多样性的持续贫困地区的影响，AIM 3。开发一个具有社区意见的数学模型，可以帮助预测长期影响 以收入为重点的癌症发病率干预措施，为社区成员，政策制定者和 研究人员在如何最好地消除持续贫困地区的癌症负担增加的指导下， 目标4。制定和实施一项职业增强计划，以促进培​​训和职业 发展多样化的跨学科早期学者学者，他们致力于晋升 通过在持续贫困地区进行研究和实践的癌症健康公平，目标5。 通过上游确定的创新和协作癌症预防和控制计划 研究中心研究项目和我们的社区合作伙伴，以制定长期可持续策略 我们的北部CA集水区以及持续的贫困中心网络。这本小说的结果 开创性的工作将为解决癌症预防和的变革性方法奠定基础 面对通过能力建设的严重经济和社会劣势的控制计划 与政策制定者，州和地方机构以及社区合作伙伴的可持续合作伙伴关系。