(1/2) Ponce Health Sciences University-Moffitt Cancer Center Partnership

(1/2) 庞塞健康科学大学-莫菲特癌症中心合作伙伴关系

• 批准号: 10658230
• 负责人: Julie Dutil
• 金额: $ 62.72万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10658230
• 关键词: Accreditation; Award; Basic Science; Behavior; Bone Marrow Transplantation; Cancer Center; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Community Outreach; Data; Development; Educational Activities; Epidemiology; Faculty; Fellowship; Florida; Funding; Genotype; Grant; Growth and Development function; Health Sciences; Hematology; Hispanic; Hospitals; Institution; Joints; Latino; Latino Population; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of ovary; Manuscripts; Medicine; Mutation; Network Infrastructure; Oncology; Operative Surgical Procedures; Outcome; Outreach Research; Participant; Patients; Peer Review; Population Research; Protocols documentation; Puerto Rico; Research; Research Personnel; Residencies; Resources; Role; Rotation; Science; Stem cell transplant; Structure; Students; Surgical Oncology; Technology; Tissue Banks; Training; Training and Education; Translational Research; Underserved Population; Universities; Vision; biobank; cancer care; cancer education; cancer health disparity; education research; improved; malignant breast neoplasm; outreach; outreach program; programs; recruit; success; sun protection

PROJECT SUMMARY/STATEMENT The Ponce Health Sciences University (PHSU) and the Moffitt Cancer Center (MCC) have forged a strong working relationship founded on seamless communication with mutual support and benefits. With Partnership resources and significant commitment from both institutions, we have established joint programs enhancing basic and clinical research, enriching cancer outreach, expanding cancer education, and creating a unique Hispanic/Latino (H/L) Biobank, leading to the development of a robust network and infrastructure necessary for a sustained long-term collaboration to improve cancer outcomes in the H/L population. The U54 Partnership’s impact includes the identification of new mutations in breast and lung cancer in H/L patients, recruitment of new faculty at PHSU and MCC, 184 community outreach educational activities for H/Ls in Florida and Puerto Rico, 240 trainee participants, 234 peer-reviewed manuscripts, and 90 grants funded out of a total of 237 submitted. Twenty Early-Stage Investigators have been supported by the Partnership. The development of the Puerto Rico BioBank (PRBB), the Quantitative Sciences Core (QSC), as well as the training of clinical researchers and the implementation of a clinical trial office at PHSU, demonstrate the broad impact realized through the Partnership. Furthermore, the Partnership had a critical role in the ACGME re-accreditation of the Hematology/Oncology Fellowship in PR, in the establishment of two stem cell transplant programs in PR by fellows trained in the MCC Bone Marrow Transplant unit, and in the establishment of an ACGME-accredited surgical residency in Ponce with surgical oncology rotations at MCC. Our vision for the U54 PACHE is to further grow and engage faculty and students in cancer medicine research that directly impacts the H/L population in FL and PR. The Partnership has the requisite components to fully execute this vision in an underserved population – a biobank, a quantitative sciences core (QSC) to analyze data, culturally sensitive outreach materials, expertise in the latest technologies, and a robust research portfolio. The bridge funding will facilitate continued sustainability of this Partnership. The four specific aims proposed in the currently funded U54 Partnership grant are: Aim 1 – To Increase the number of researchers at PHSU focused on basic/translational research in cancer and to augment the number of researchers in cancer health disparities at MCC. This is facilitated with joint projects in ovarian and breast cancer. Aim 2 – To further develop outreach programs and research efforts in H/L communities at both PHSU and MCC. An epidemiological project will examine the impact of receipt of MC1R genotypes on personal sun protection behaviors. Aim 3 – To increase support for basic, translational, and clinical research in the H/L population by establishing the QSC and further developing the PRBB. The MCC Total Cancer Care protocol will be developed in Ponce hospitals and leveraged by the PRBB to facilitate tissue collection. Aim 4 – To provide comprehensive and structured student research education at both PHSU and MCC to facilitate the expansion and success of cancer researchers and clinicians in the H/L population.

项目摘要/声明 Ponce Health Sciences University（PHSU）和Moffitt癌症中心（MCC）忘记了一个强大的 工作关​​系建立在无缝沟通和相互支持和利益的基础上。与伙伴关系 资源和两个机构的重大承诺，我们已经建立了共同计划 基础和临床研究，丰富癌症外展，扩大癌症教育并创造独特的 西班牙裔/拉丁裔（H/L）生物库，导致建立坚固的网络和基础设施所需的基础设施 持续的长期合作，以改善H/L人群的癌症结局。 U54合作伙伴关系 影响包括鉴定H/L患者乳腺癌和肺癌的新突变，招募新的 PHSU和MCC的教职员工，佛罗里达州H/LS的184个社区外展教育活动，波多黎各， 240名受训者参与者，234名同行评审的手稿和90个赠款，共有237名赠款。 二十个早期调查人员得到了合作伙伴关系的支持。波多黎各的发展 Biobank（PRBB），定量科学核心（QSC），以及临床研究人员和 在PHSU实施临床审判办公室，证明了通过合作伙伴关系实现的广泛影响。 此外，伙伴关系在血液学/肿瘤学的ACGME重新认证中起着至关重要的作用 PR研究金，在MCC中受过培训的研究员在PR建立两个干细胞移植程序中 骨髓移植单元，以及在Ponce建立ACGME认可的手术居住 MCC的手术肿瘤学旋转。我们对U54 PACHE的愿景是进一步增长和参与教师 和癌症医学研究的学生直接影响FL和PR的H/L人群。伙伴关系 有必要的组成部分可以在服务欠缺的人群中充分执行这一愿景 - 生物库，定量 科学核心（QSC）分析数据，对文化敏感的外展材料，最新技术专业知识， 以及强大的研究组合。桥梁资金将促进这种合作伙伴关系的持续可持续性。 当前资助的U54合伙赠款中提出的四个具体目标是：目标1 - 增加 PHSU的研究人员的数量重点是癌症的基本/转化研究，并增加了数量 MCC癌症健康差异研究人员的研究人员。这是由卵巢和乳房的联合项目准备的 癌症。目标2 - 进一步开发两个PHSU的H/L社区的外展计划和研究工作 和mcc。一个流行病学项目将检查收到MC1R基因型对个人太阳的影响 保护行为。目标3 - 增加对H/L的基本，翻译和临床研究的支持 人口通过建立QSC并进一步发展PRBB。 MCC总癌症护理方案将 可以在Ponce医院开发，并由PRBB杠杆来促进组织收集。目标4 - 提供 PHSU和MCC的全面和结构化的学生研究教育，以促进扩展 癌症研究人员和临床医生在H/L人群中的成功。