2/2 Ponce Health Sciences University-Moffitt Cancer Center Partnership

2/2 庞塞健康科学大学-莫菲特癌症中心合作伙伴关系

基本信息

批准号：
10762077
负责人：
Julie Dutil
金额：
$ 141.45万
依托单位：
H. LEE MOFFITT CANCER CTR & RES INST
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-09-24 至 2028-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10762077
关键词：
Accreditation Achievement Address Admixture Advocate Affect Basic Cancer Research Basic Science Bay Region Biological COVID-19 pandemic Cancer Center Cancer Patient Caregivers Clinical Clinical Research Collaborations Communication Communities Community Developments Community Health Community Health Education Community Outreach Complex Comprehensive Cancer Center Development Direct Costs Doctor of Philosophy Earthquakes Education Educational Materials Ensure Environment Evaluation Evaluation Research Evolution Faculty Florida Fostering Funding Genetic Genomics Goals Grant Growth Health Health Disparities Research Health Educators Health Sciences Health Services Accessibility Hematology Hispanic Hurricane Infrastructure Institution Intervention Joints Language Latino Latino Population Learning Malignant Neoplasms Medical Medical Students Minority Participation NCI-Designated Cancer Center Natural Disasters Oncology Operative Surgical Procedures Outcome Peer Review Population Postdoctoral Fellow Poverty Preparation Process Productivity Psychological Factors Publications Puerto Rico Reduce health disparities Research Research Personnel Research Project Grants Research Support Residencies Resources Science Specimen Tissue Microarray Training Universities anticancer research biobank cancer clinical trial cancer education cancer health disparity career catalyst community engagement disparity gap doctoral student empowerment experience forging genomic data graduate medical education health disparity improved innovation inter-institutional novel outreach outreach program programs recruit resilience social factors social media translational cancer research undergraduate student

项目摘要

ABSTRACT | OVERALL The Hispanic/Latino (H/L) communities in the Ponce and Tampa Bay regions experience both shared and unique challenges associated with poverty, access to care, and language. The Ponce Health Sciences University (PHSU) in Puerto Rico (PR) and the Moffitt Cancer Center (MCC) in Florida have forged a strong relationship and leveraged their respective strengths and resources to address these needs with the ultimate goal of eliminating cancer health disparities. The 15-year Partnership has established joint programs for basic and clinical research, cancer outreach, cancer education, and training, and biobanking, building networks of investigators focused on cancer disparities and infrastructure for sustained long-term collaboration. Combined with the establishment and growth of a unique biobanking resource for H/L and the integration of quantitative sciences expertise, this dynamic environment is a catalyst for the recruitment of new faculty at PHSU in basic and translational cancer research, increases the health disparities research focus at MCC and stimulates innovative cancer research. To ensure a durable impact, the Partnership fosters the development of cancer researchers and clinicians through an exchange of research and medical trainees between institutions and supporting the successful advancement of Early-Stage Investigators (ESIs). The Partnership and our outreach activities continue to be integral in promoting cancer health in our H/L communities and has provided vital support for overcoming two major hurricanes, devastating earthquakes, and the COVID pandemic. The challenges, achievements, and lessons learned to provide a strong basis to guide the evolution and further expansion of this Partnership, whose primary goals are to reduce cancer disparities in the Hispanic/Latino (H/L) communities and to contribute to the elimination of health disparities in the population at large. The specific aims for the U54 Partnership renewal are (1) Increase Partnership investigators and collaborations committed to innovative cancer health disparities research, creating long-term sustainability. This will be accomplished through the engagement of faculty and ESIs with resources to support collaborations, grant preparations, publications, and networking. (2) Identify and foster the growth of diverse trainees for a career in cancer research and health disparities. We will support the recruitment and development of trainees from diverse backgrounds across the career continuum with an emphasis on H/L. (3) Support novel research projects that will contribute to the identification and elimination of cancer health disparities in H/L. We will foster the development of projects that investigate the biological basis, psychological and social factors of cancer disparities through a rigorous evaluation of research projects that have the potential to reduce specific disparity gaps. (4) Increase community engagement in cancer health disparities research. This will be accomplished by fostering community engagement, including bi-directional activities, education, increased social media presence, and dialogue with the research component and activities of our Community Health Educator.

摘要|全面的庞塞和坦帕湾地区的西班牙裔/拉丁裔（H/L）社区经历了共享和独特的经历与贫困，获得护理和语言有关的挑战。 Ponce Health Sciences University （PHSU）在波多黎各（PR）和佛罗里达州的莫菲特癌症中心（MCC）建立了牢固的关系并利用各自的优势和资源来满足这些需求消除癌症健康差异。 15年的合作伙伴关系已建立了基本的联合计划和临床研究，癌症外展，癌症教育和培训以及生物群，建立网络研究人员专注于癌症的差异和基础设施，以进行长期合作。合并随着用于H/L的独特生物群体的建立和增长以及定量的整合科学专业知识，这种动态环境是基本PHSU招募新教师的催化剂和转化癌症研究，增加了MCC的健康差异研究重点并刺激创新的癌症研究。为了确保持久影响，伙伴关系促进了癌症的发展研究人员和临床医生通过在机构和机构之间进行研究和医疗学员的交流支持早期研究人员（ESIS）的成功发展。伙伴关系和我们的外展活动在促进我们的H/L社区的癌症健康方面继续是不可或缺的，并提供了重要的支持为了克服两次主要飓风，毁灭性地震和库维德大流行。挑战，成就和经验教训提供了强大的基础来指导进化和进一步扩展伙伴关系，其主要目标是减少西班牙裔/拉丁裔（H/L）社区的癌症差异为消除整个人口的健康差异做出贡献。 U54的具体目标合作伙伴关系的更新是（1）增加致力于创新的合作伙伴调查员和合作癌症健康差异研究，创造了长期的可持续性。这将通过教师和ESI与资源的参与，以支持合作，赠款准备，出版物和联网。（2）确定并促进癌症研究和健康职业的不同学员的成长差异。我们将支持来自各个背景的学员的招聘和成长职业连续性，重点是H/L。（3）支持新的研究项目，将有助于 H/L中的癌症健康差异的鉴定和消除。我们将促进项目的发展通过严格的评估有可能减少特定差异差距的研究项目。（4）增加社区参与癌症健康差异研究。这将通过培养社区来实现参与，包括双向活动，教育，社交媒体的增加以及与我们社区健康教育者的研究组成部分和活动。

项目成果

期刊论文数量（24）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Early2 factor (E2F) deregulation is a prognostic and predictive biomarker in lung adenocarcinoma.

DOI：
10.18632/oncotarget.12672
发表时间：
2016-12-13
期刊：
Oncotarget
影响因子：
0
作者：
Chen L;Kurtyka CA;Welsh EA;Rivera JI;Engel BE;Muñoz-Antonia T;Yoder SJ;Eschrich SA;Creelan BC;Chiappori AA;Gray JE;Ramirez JL;Rosell R;Schabath MB;Haura EB;Chen DT;Cress WD
通讯作者：
Cress WD

The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.