Initiative to Maximize Research Education in Genomics: Diversity Action Plan (DAP)

最大化基因组学研究教育的倡议：多样性行动计划（DAP）

• 批准号: 10631939
• 负责人: RICHARD A GIBBS
• 金额: $ 29.97万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-19 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10631939
• 关键词: Address; African American; African American population; African American student; Area; Atmosphere; Award; Bachelor' s Degree; Behavioral Research; Bioinformatics; Biological Sciences; Biomedical Research; Clinical Research; Competence; Country; Critical Thinking; Data; Disparity; Doctor of Philosophy; Doctor' s Degree; Education; Educational Activities; Educational Curriculum; Engineering; Faculty; Foundations; Funding; Genetic; Genetic Variation; Genomics; Goals; Graduate Education; Health; Hispanic Populations; Human; Human Genetics; Human Genome Project; Institution; Internships; Intervention; Journals; Knowledge; Lead; Medicine; Minority; Minority Groups; Molecular Genetics; National Human Genome Research Institute; Native Americans; Outcome; Postbaccalaureate; Recording of previous events; Research; Research Training; STEM career; STEM field; Science; Science, Technology, Engineering and Mathematics; Scientist; Students; Training; Training Activity; Training Programs; Training and Education; Underrepresented Populations; Underrepresented Students; United States; Visit; career; college; education research; educational atmosphere; experience; graduate school; graduate student; human disease; human genome sequencing; improved; innovation; interest; intervention program; next generation; pre-doctoral; prevent; programs; recruit; skills; student participation; student retention; success; successful intervention; summer internship; summer research; summer student; therapy development; undergraduate student

Project Summary/Abstract The United States (US) science, technology, engineering, and mathematics (STEM) workforce has been a world leader in biomedical research for decades, and in the 21st century the US took the lead in sequencing the human genome. The STEM workforce has also faced the challenge of increasing participation of under-represented (UR) populations to remain competitive in science and engineering. The National Human Genome Research Institute (NHGRI) had the foresight from the outset of the Human Genome Project to include training (Diversity Action Plan-DAP) that would address this shortage as the field developed. In spite of many national interventions, several minority groups remain underrepresented at all degree and professional career levels.1-2 For example, of the 76,447 doctorate degrees awarded in the biological sciences in 2012, only 3,677 (4.8%) were African Americans, 4,463 (5.8%) were Hispanics, and 314 (0.41%) were Native Americans. 1 Therefore, the development of intervention programs seeking to ameliorate these disparities within science research become important and necessary. The long term goal of this proposal is to increase UR PhDs in genomics and bioinformatics. We will approach this goal in two specific aims. Aim 1 will provide six undergraduate and 8 post-baccalaureate students DI training activities that result in 75% completing the program with greater genomics/bioinformatics knowledge and lab-based critical thinking skills appropriate for success in graduate school. Although the number of UR PhDs is low in biomedical research, in the field of bioinformatics there is a shortage of US trained scientists in this area and the UR groups are even more severely limited in this new field. Aim 2 plans to recruit and retain 50% of DI trainees as graduate students in the Molecular and Human Genetics Department at Baylor College of Medicine. The African American applicant pool is lowest among all under-represented groups that apply to the MHG department. We will address these aims, using research training as our foundation, in the HGSC-DI summer research internship and Post-baccalaureate programs. Our program data indicates the following DI results: 72% of our post-baccalaureate students enter PhD programs; 100% of pre-doctoral alumni are retained in PhD programs; and 100% of the summer interns obtain bachelor's degrees. We have proven ability to recruit and retain students in STEM. The overall impact of this proposal will increase the number of UR PhDs in genomics and trained in bioinformatics.

项目摘要/摘要 美国（美国）科学，技术，工程和数学（STEM）劳动力一直是 几十年来，世界领域的世界领导者，在21世纪，美国领导着 测序人基因组。 STEM劳动力也面临着增加的挑战 代表性不足（UR）人群的参与在科学和工程学中保持竞争力。这 国家人类基因组研究所（NHGRI）从人类开始就具有远见卓识 基因组项目将包括培训（多样性行动计划），以解决这一短缺 田野开发了。尽管有许多国家干预措施，但几个少数群体的人数仍然不足 例如，在所有程度和职业级别。例如，1-2 2012年的生物科学，只有3,677（4.8％）是非裔美国人，4,463（5.8％）是西班牙裔， 314（0.41％）是美洲原住民。 1因此，开发干预计划 试图改善科学研究中的这些差异变得重要和必要。 该提案的长期目标是增加基因组学和生物信息学的博士学位。我们将 在两个具体目标中实现这一目标。 AIM 1将提供六个本科生和8个后肠龙 学生DI培训活动，导致75％的人完成该计划 基因组学/生物信息学知识和基于实验室的批判性思维技能适合于成功 研究所。尽管在生物医学研究中，UR博士的数量很少 生物信息学缺乏该领域的美国训练有素的科学家，而UR的团体甚至更多 在这个新领域受到严格限制。 AIM 2计划招募和保留50％的DI学员的计划 在贝勒医学院的分子和人类遗传学系中。非裔美国人 在适用于MHG部门的所有代表性群体中，申请人池最低。我们将 在HGSC-DI夏季研究中，以研究培训为基础，以我们的基础来解决这些目标 实习和后库龙计划。我们的程序数据表示以下DI结果：72％ 我们的学士后学生进入博士学位课程； 100％的博士前校友保留在 博士课程； 100％的暑期实习生获得学士学位。我们有证明的能力 招募和留住学生。该提案的总体影响将增加UR的数量 基因组学博士学位和生物信息学培训。