Pilot of Two CAM Tratments for Maintenance Wt Loss

两种 CAM 处理维护重量损失的试验

• 批准号: 6792588
• 负责人: CHARLES R ELDER
• 金额: $ 19.75万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-15 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6792588
• 关键词: acupuncture /acupressure; alternative medicine; behavior therapy; behavioral /social science research tag; body physical activity; clinical research; clinical trials; diet; disease /disorder prevention /control; group therapy; human subject; human therapy evaluation; longitudinal human study; nutrient intake activity; obesity; outcomes research; quality of life; questionnaires; self care; social psychology; social support network; weight control; weight loss

DESCRIPTION (provided by applicant): The prevalence of obesity is at epidemic proportions, 60% of US adults are overweight or obese. Obesity contributes to chronic diseases-diabetes, CVD, hypertension, diabetes, cancer and osteoarthritis and to escalating health care costs. Weight loss can have a substantial impact on reducing these conditions. Substantial efforts have been made in developing effective short-term wt. loss programs using behavioral treatments. However, long-term maintenance of wt. loss continues to be problematic - many individuals regain the wt. lost within a year. Innovative intervention options are critically needed to help people successfully maintain weight loss and to fight the obesity epidemic. Complementary and alternative medicine (CAM) approaches - mind-body, energy healing, and Traditional Chinese Medicine (TCM) approaches - may hold great promise for helping improve the maintenance of wt. loss. Despite long historical use, significant anecdotal and case report information on benefits and efficacy, plausible biologic mechanisms for action and great consumer interest, there is little data available on the evaluation of these CAM therapies for wt. maintenance or wt. loss. The goal of this study is to pilot test in a group of overweight-obese individuals the feasibility and acceptability and indications of efficacy of two CAM treatments, qigong, and acupressure-TAT, for improving long term maintenance of wt. loss. The design is a randomized, controlled 3-arm study: 1) Control, 2) qigong maintenance and 3) Acupressure-TAT maintenance, with 30 participants per group. All participants receive a standard 12-week behavioral wt. loss program. Following this, participants are randomized to receive the maintenance interventions and are followed for 6 months. Measurements occur at screening, baseline, and 12, and 24 post-randomization. Outcomes include: wt. change, diet, physical activity, self-reported use of the maintenance techniques, acceptability and satisfaction with the approaches as well as a variety of psychosocial parameters that may be mediators or moderated by the intervention (QOL, perceived stress, etc.). Information from this study will be used to develop a larger randomized trial to evaluate different maintenance approaches to improve long-term maintenance of wt. loss.

描述（由申请人提供）：肥胖症的流行已达到流行病的程度，60% 的美国成年人超重或肥胖。肥胖会导致糖尿病、心血管疾病、高血压、糖尿病、癌症和骨关节炎等慢性疾病，并导致医疗费用不断上升。减肥可以对减少这些情况产生重大影响。在开发有效的短期重量方面已经做出了大量努力。使用行为治疗的损失计划。然而，长期维持重量。损失仍然是一个问题——许多人重新获得了重量。一年内丢失。迫切需要创新的干预方案来帮助人们成功维持体重减轻并对抗肥胖流行。补充和替代医学 (CAM) 方法 - 身心疗法、能量疗法和传统中医 (TCM) 方法 - 可能在帮助改善体重维持方面具有巨大前景。损失。尽管有着悠久的使用历史、关于益处和功效的重要轶事和病例报告信息、合理的生物学作用机制以及消费者的巨大兴趣，但关于这些 CAM 疗法对 wt 的评估数据却很少。维护或重量。损失。本研究的目的是在一组超重肥胖个体中试点测试两种 CAM 治疗（气功和穴位按摩 TAT）的可行性、可接受性和功效适应症，以改善体重的长期维持。损失。该设计是一项随机、对照 3 臂研究：1) 对照，2) 气功维持和 3) 指压 TAT 维持，每组 30 名参与者。所有参与者都会收到标准的 12 周行为权重。损失计划。此后，参与者被随机接受维持干预措施，并随访 6 个月。测量在筛选、基线以及随机化后 12 和 24 日进行。结果包括：重量。变化、饮食、身体活动、自我报告的维持技术的使用、对方法的可接受性和满意度以及可能是干预措施的中介或调节的各种心理社会参数（生活质量、感知压力等）。这项研究的信息将用于开展更大规模的随机试验，以评估不同的维护方法，以改善野生动物的长期维护。损失。

项目成果

Randomized trial of two mind-body interventions for weight-loss maintenance.

两种维持减肥身心干预措施的随机试验。

• 发表时间: 2007-01
• 作者: Elder, Charles;Ritenbaugh, Cheryl;Mist, Scott;Aickin, Mikel;Schneider, Jennifer;Zwickey, Heather;Elmer, Pat
• 通讯作者: Elmer, Pat