Career Enhancement Program

职业提升计划

基本信息

批准号：
10456748
负责人：
JENNIFER A PIETENPOL
金额：
$ 7.9万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-08-07 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10456748
关键词：
Academic Medical Centers Applied Research Area Award Basic Science Breast Budgets Cancer Center Capital Clinical Clinical Oncology Supplement (K12)Clinical Research Clinical and Translational Science Awards Doctor of Philosophy Elements Extramural Activities Faculty Funding Goals Grant Health Healthcare Home Human Incidence Individual K-Series Research Career Programs Knowledge Laboratories Lead Mentorship Morbidity - disease rate Pathway interactions Physicians Play Population Research Program Development Publications Research Research Personnel Role SECTM1 gene Science Scientist Talents Training Training Programs Translating Translational Research Underrepresented Minority United States National Institutes of Health Universities Woman Work anticancer research base career career development cost malignant breast neoplasm member minority investigator mortality population based population health programs recruit skills success training opportunity translational scientist

项目摘要

PROJECT SUMMARY/ABSTRACT: CAREER ENHANCEMENT PROGRAM The Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University Medical Center (VUMC), and Vanderbilt University (VU), collectively referred to as “Vanderbilt”, are deeply invested in continuously expanding the quantity and quality of opportunities for career-long training in translational research available to physicians, physician-scientists and researchers across the continuum from basic to translational to clinical to population- based science. The NCI-funded Vanderbilt SPORE programs have played an integral role in enhancing the careers of many faculty members and catalyzing talented basic scientists to translate their fundamental discoveries to translational endpoints, as evidenced by projects in the current and proposed SPORE. VUMC has 44 NIH and other federal institutional training grants. It is home to seven K12s, Vanderbilt's Clinical and Translational Research Scholars KL2 awards from the Clinical and Translational Science Award (CTSA), and numerous individual K awardees. Each year more than 300 trainees are appointed to career development programs including T32s, F31s, F32s, and K awards or the equivalent. The majority of trainees are engaged in collaborative work that has direct implications for human health, healthcare or population health. These actions are of vital importance for the success of the Breast SPORE, as well as for our ultimate goal: a reduction in the incidence, morbidity and mortality resulting from breast cancer. To achieve these overall goals, the SPORE includes a Career Enhancement Program (CEP) with two complementary areas of career enhancement focus: a physician-scientist/translational investigator (MD and MD/PhD) and a basic or population research scientist (PhD). For the first area of focus, the Breast SPORE has built upon two successful NIH funded training programs: the Vanderbilt Physician Scientist Development (VPSD) Program and the Vanderbilt Clinical Oncology Research Career Development Program (VCORCDP, K12). The second area of focus of the CEP is geared towards early, mid-career or senior basic scientists (PhDs) who wish to focus their research in breast cancer. Our highly successful CEP has supported eleven investigators (thirteen total awards) in the current funding period; three physician-scientists and eight basic scientists. Thirty publications have resulted from CEP awardees. Six of the awardees have obtained extramural grants for a total combined budget of over $9.3M (total costs). In addition, several CEP recipients have become major contributors in the competitive renewal of the Breast SPORE with two awardees co-leading two of the translational projects in the proposed SPORE; two other awardees working with project leaders as basic co-investigators and one awardee working with core directors as a co-investigator. The CEP will continue to (1) provide translational research mentorship, training and opportunities for investigators to develop the knowledge, skills and expertise to successfully pursue independent, extramurally-funded careers focused in translational research in breast cancer, and (2) make it a high priority to recruit underrepresented investigators into breast cancer research.

项目摘要/摘要：职业提升计划范德比尔特-英格拉姆癌症中心 (VICC)、范德比尔特大学医学中心 (VUMC) 和范德比尔特大学（VU），统称为“范德比尔特大学”，大力投资于不断扩大为医生提供转化研究职业生涯培训机会的数量和质量，从基础到转化到临床到人群的连续体中的医师科学家和研究人员 NCI 资助的范德比尔特 SPORE 项目在增强许多教职员工的职业生涯，并催化有才华的基础科学家转化他们的基础知识当前和拟议的 SPORE 项目证明了转化终点的发现。拥有 44 项 NIH 和其他联邦机构培训资助，拥有 7 个 K12、范德比尔特临床和临床中心。临床和转化科学奖 (CTSA) 授予的转化研究学者 KL2 奖，以及每年有超过 300 名学员被任命从事职业发展。计划包括 T32s、F31s、F32s 和 K 奖励或同等级别的学员。这些行动对人类健康、医疗保健或人口健康有直接影响。对于乳房孢子的成功以及我们的最终目标：减少为了实现这些总体目标，SPORE 制定了乳腺癌的发病率、发病率和死亡率。包括职业提升计划 (CEP)，其中包含两个互补的职业提升重点领域：医师科学家/转化研究者（医学博士和医学博士/博士）和基础或人口研究科学家（博士）对于第一个重点领域，乳房 SPORE 建立在 NIH 资助的两次成功培训的基础上。计划：范德比尔特医师科学家发展 (VPSD) 计划和范德比尔特临床肿瘤学研究职业发展计划（VCORCDP，K12）。CEP 的第二个重点领域是。面向希望将研究重点放在乳腺方面的早期、中期或高级基础科学家（博士）我们非常成功的 CEP 在当前的研究中为 11 名研究人员（总共 13 项奖项）提供了支持。资助期内，CEP 发表了 30 篇论文。其中六名获奖者获得了总预算超过 930 万美元的校外补助金。（总成本）此外，一些 CEP 接受者已成为竞争性更新的主要贡献者。乳房 SPORE 与两名获奖者共同领导拟议的 SPORE 中的两个转化项目；其他获奖者作为基本联合研究员与项目负责人合作，一名获奖者与核心人员合作 CEP 将继续 (1) 提供转化研究指导和培训。以及研究人员发展知识、技能和专业知识以成功追求的机会独立的、校外资助的职业，专注于乳腺癌的转化研究，(2) 使其成为高度优先招募代表性不足的研究人员参与乳腺癌研究。