Biomedical Research Excellence, Epigenomics of Development and Disease

卓越的生物医学研究、发育和疾病的表观基因组学

• 批准号: 10448460
• 负责人: ROXANNE A VAUGHAN
• 金额: $ 88.95万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-10 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10448460
• 关键词: Applications Grants; Area; Bioinformatics; Biological Models; Biomedical Research; Biometry; Budgets; Canada; Career Mobility; Centers of Research Excellence; Clinical; Collaborations; Communities; Computational Biology; Development; Disease; Educational workshop; Ensure; Epigenetic Process; Evaluation; Extramural Activities; Faculty; FarGo; Financial Support; Fostering; Funding; Future; Genomics; Goals; Grant; Grant Review; Group Meetings; Growth; Individual; Infrastructure; International; Letters; Manitoba; Medical center; Mentors; Mentorship; Mission; North Dakota; Outcome; Pilot Projects; Research; Research Personnel; Research Project Grants; Resources; Series; Services; Site Visit; Structure; Therapeutic; Training; Training Activity; United States National Institutes of Health; Universities; Work; Writing; career; clinical application; education resources; epigenomics; innovation; meetings; model development; novel; professor; programs; recruit; success; symposium

UNIVERSITY OF NORTH DAKOTA EPIGENOMICS OF DEVELOPMENT AND DISEASE ADMINISTRATIVE CORE SUMMARY The goal of the Administrative Core is to promote the growth and success of the COBRE centered on the Epigenomics of Development and Disease by consolidating, centralizing and managing all necessary resources. The core will support investigators whose work focuses on mechanisms underlying epigenetic changes in models of development and disease. To ensure success of our researchers and promote long-term sustainability and growth of our program, we will provide administrative and/or financial support for essential aspects of our group’s activities. These include the following: (1) Implement a comprehensive and individualized Mentoring Program for our Project Leaders at multiple stages of their careers, (2) Provide oversight and evaluation of the Mentoring Program through the Internal Advisory Board, External Advisory Board, and UND Department of Education Resources, (3) Fund new research projects centered on epigenetics of disease and development though Pilot Grant support, (4) Recruit new investigators whose research is focused on understanding epigenetic mechanisms using unique model systems of diseases, (5) Provide structured opportunities (e.g. seminars, symposia) to establish and facilitate productive scientific interactions within the group, (6) Enhance the wider epigenetics community at UND through continuation of epigenetics- themed seminars and symposia, (7) Raise the national profile of the epigenetics group, (8) Provide administrative support for the Genomics Core and its associated training activities, and (9) Foster increased collaborations with other UND and regional groups including UND COBRE, ND INBRE, DACCOTA, etc. These functions will enhance our ability to execute innovative, high-quality research that will lead to increased understanding of epigenetic mechanisms in pathophysiological conditions, with the potential for future therapeutic and clinical applications.

北达科他大学 发育和疾病的表观基因组学 行政核心 概括 行政核心的目的是促进cobre的增长和成功，以中心为中心 通过巩固，集中和管理所有必要的所有必要的发展和疾病的表观基因组学 资源。核心将支持研究人员的工作重点是表观遗传学的机制 发展和疾病模型的变化。确保我们的研究人员的成功并促进长期 我们计划的可持续性和增长，我们将提供行政和/或财务支持 我们小组活动的各个方面。这些包括以下内容：（1）实施全面和 在职业生涯的多个阶段为我们的项目负责人的个性化指导计划，（2）提供 通过内部咨询委员会（外部咨询）对指导计划的监督和评估 董事会和教育部资源，（3）资助以表观遗传学为中心的新研究项目 疾病和发展尽管试点赠款支持，但（4）招募了研究的新调查人员的研究是 专注于使用独特的疾病模型系统理解表观遗传机制，（5）提供 结构化的机会（例如，半座，研讨会）来建立和促进产品科学互动 在小组内，（6）通过持续表观遗传学 - 主题的半小伙和座谈会，（7）提高表观遗传学组的国家形象，（8）提供 对基因组学核心及其相关培训活动的行政支持，以及（9）促进 与其他UND和区域团体的合作，包括UND COBRE，ND INBRE，DACCOTA等 这些功能将增强我们执行创新，高质量研究的能力，这将导致增加 了解病理生理条件下的表观遗传机制，并具有未来的潜力 治疗和临床应用。