Indiana Diabetes Research Center

印第安纳州糖尿病研究中心

• 批准号: 9509434
• 负责人: Raghavendra G Mirmira
• 金额: $ 93.57万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-06 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9509434
• 关键词: Advocate; Animals; Area; Award; Awareness; Basic Science; Biomedical Engineering; Child; Clinical Research; Collaborations; Communities; Core Facility; Diabetes Mellitus; Diabetic Diet; Diagnosis; Disease; Educational Activities; Educational workshop; Endocrine System Diseases; Ensure; Evolution; Extramural Activities; Family suidae; Fostering; Foundations; Funding; Future; Goals; Grant; Growth; Human; Indiana; Individual; Influentials; Knowledge; Learning; Mentorship; Metabolic Diseases; Metabolism; Methodological Studies; Microscopy; Mission; Nutritional Study; Obesity; Population; Postdoctoral Fellow; Prediabetes syndrome; Research; Research Activity; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Research Support; Resources; Rodent; Scientist; Series; Services; Structure; Students; Talents; Technology; Training; Training Support; Translational Research; Translations; Universities; Visit; base; collaborative environment; educational atmosphere; human subject; human tissue; innovation; islet; medical schools; metabolic abnormality assessment; novel; nutrition; pre-clinical research; programs; public health relevance; ranpirnase; symposium; translational scientist

 DESCRIPTION (provided by applicant): This P30 application represents the culmination of years of an Indiana University School of Medicine (IUSM) effort to build its diabetes and obesity research base and to focus on specific basic science and translational research themes that represent areas of national priority. An important component of this application is the inclusion of collaborative researchers at nearby Purdue University, whose programs in obesity, nutrition, and biomedical engineering are complementary to the research themes at IUSM. Support of this P30 application will bolster diabetes research in Indiana by providing a dedicated resource that allows diabetes research and educational activities to be centralized and focused on the fundamental themes of our Research Base, that subsidizes Research Core services to encourage their use for innovation and translation, and that permits innovative research support for new investigators to maintain a pipeline of talented diabetes-oriented researchers. The mission of the Indiana Diabetes Research Center (IDRC) is to foster knowledge, support training, and promote basic and translational research in diabetes and related metabolic disorders, and their complications. The IDRC consists of a Research Base of 64 highly collaborative investigators at Indiana University School of Medicine and nearby Purdue University, whose research collectively will be augmented by 5 state-of-the-art Research Cores (Islet, Rodent, Microscopy, Swine, and Translation Cores). An Enrichment Program, supported by 5 T32 training grants, will enhance learning and discovery. A Pilot and Feasibility Program will grow the Research Base by providing funding to highly promising young investigators. An Administrative Core will oversee governance of the IDRC, and will receive input from an Executive Committee, an Internal Advisory Board, and an External Advisory Board of world-renowned diabetes/metabolism research leaders. The Aims of the IDRC will be to (1) Promote high impact scientific discoveries by establishing Research Cores that facilitate collaborations and the use of state-of-the-art methodologies and human studies in diabetes research; (2) Enhance a highly collaborative environment that promotes learning and encourages interaction among investigators; (3) Support the training and innovative research of a burgeoning pool of superb investigators with the potential to become future leaders in diabetes research; (4) Build and strengthen the diabetes research base, support infrastructure to ensure ongoing growth and innovation, and engage with the local community to raise diabetes awareness and involvement.

 描述（由申请人提供）：这份 P30 申请代表了印第安纳大学医学院 (IUSM) 多年来努力建立糖尿病和肥胖研究基地并专注于代表国家领域的特定基础科学和转化研究主题的成果。该应用程序的一个重要组成部分是附近普渡大学的合作研究人员的参与，他们的肥胖、营养和生物医学工程项目与 IUSM 的研究主题相辅相成，对这一 P30 应用程序的支持将支持印第安纳州的糖尿病研究。通过提供专用资源，使糖尿病研究和教育活动能够集中并集中于我们研究基地的基本主题，补贴研究核心服务以鼓励其用于创新和转化，并允许为新研究人员提供创新研究支持印第安纳糖尿病研究中心 (IDRC) 的使命是培养糖​​尿病和相关代谢性疾病及其并发症的知识、支持培训并促进基础和转化研究。由 64 名高度协作的研究人员组成的研究基地位于印第安纳大学医学院和附近的普渡大学，其研究将通过 5 个最先进的研究核心（胰岛、啮齿动物、显微镜、猪和翻译核心）得到增强，并得到 5 个 T32 的支持。培训补助金，将加强学习和发现。 试点和可行性计划将通过向有前途的年轻研究人员提供资金来扩大研究基地。 行政核心将监督 IDRC 的治理，并将接受来自IDRC 的目标是 (1) 通过建立促进合作和使用的研究核心来促进高影响力的科学发现。糖尿病研究中最先进的方法和人体研究；(2) 加强高度协作的环境，促进研究人员之间的学习和鼓励互动；(3) 支持不断壮大的优秀研究人员的培训和创新研究；成为糖尿病研究未来领导者的潜力；（4）建立和加强糖尿病研究基地，支持基础设施以确保持续增长和创新，并与当地社区合作以提高糖尿病意识和参与度。