UT Southwestern Center for Translational Medicine

德州大学西南转化医学中心

• 批准号: 10349035
• 负责人: ROBERT Daniel TOTO
• 金额: $ 802.96万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-26 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10349035
• 关键词: Address; Adoption; Artificial Intelligence; Basic Science; Clinical; Clinical Research; Clinical Trials; Collaborations; Communication; Communities; Data; Data Collection; Education; Ensure; Entrepreneurship; Environment; Faculty; Family; Fostering; Foundations; Funding; Gap Junctions; Goals; Health; Health Personnel; Healthcare; Healthcare Systems; Heterogeneity; Incentives; Individual; Industry; Informatics; Institution; Intervention; Leadership; Longevity; Mentors; Methods; Mission; Outcome; Patients; Phase; Population; Population Heterogeneity; Process; Published Comment; Qualitative Methods; Reproducibility; Research; Research Training; Resources; Rural Community; Rural Population; Science; Scientist; Services; Special Population; Teaching Hospitals; Technology; Testing; Texas; Training; Training Programs; Training Support; Training and Education; Translating; Translational Research; Translations; Underserved Population; Urban Community; Urban Population; academic program; biomedical scientist; catalyst; clinical practice; collaborative environment; community engagement; design; equity diversity and inclusion; ethnic diversity; improved; informatics training; innovation; member; multimodality; novel; novel strategies; personalized medicine; point of care; population health; pre-clinical; programs; racial diversity; recruit; research to practice; skills; success; tool; translational medicine; user-friendly

Contact PD/PI: Toto, Robert D OVERALL: PROJECT SUMMARY/ABSTRACT The Center for Translational Medicine (CTM) at UT Southwestern is a collaboration among 7 academic institutions, 5 health care systems, 6 teaching hospitals and the North Texas community. Our mission is to improve health in local and global communities through innovation and education. Over the past two funding cycles, our CTSA catalyzed innovation and transformed the culture and landscape of our program Hub. We have trained >1,000 members of the translational workforce, co-led the formation of the Accrual to Clinical Trials CTSA network and established new translational technologies, methods, and processes critical to the translational process at every level. We engaged our local communities early on in the design and conduct of clinical research. We also formed new collaborative research services and education and training programs designed to address the top health challenges of our community and the nation. Through these efforts, the CTM has generated considerable momentum toward advancing translational science propelled by a highly collaborative environment that is hard-wired for Team Science and Community Engagement. Over the next 5 years, we will optimize the organization of our CTSA Hub for more efficient translation of biomedical discoveries into interventions that will ultimately result in the improved health of both our local populations and, in collaboration with the CTSA Network, the broader U.S. population. We will discover, develop, demonstrate, and disseminate new informatics and artificial intelligence solutions to challenging problems in translation at all levels. In collaboration with Hub partners and relevant national CTSA networks, we propose to develop new methods and processes to further the integration of research into practice at the point of care. Building on our success, we are now poised to achieve the five key objectives of the CTSA Program and the Center for Translational Medicine with the following Specific Aims: Aim 1. Produce a well-trained, highly skilled, diverse Translational Workforce. Aim 2. Inculcate Community Engagement and Team Science. Aim 3. Integrate diverse populations across the lifespan into clinical and translational research. Aim 4. Promote innovation and new scientific Methods and Processes. Aim 5. Develop innovative Informatics solutions to overcome translational roadblocks. Aim 6. Increase Workforce Heterogeneity. Impact: With our highly-integrated dynamic research and training environment in place, our Hub will have a powerful and sustained impact on the field of translational science. We will make a major leap forward in the scope, efficiency, and quality of clinical and translational research for the benefit of our Hub and the national consortium. We will collaborate with the Center for Leading Innovation and Collaboration, the Trial Innovation Network, and the Center for Data to Health to bridge the gap between scientific discovery and improved health. Project Summary/Abstract Page 164 Contact PD/PI: Toto, Robert D O. OVERALL:

联系PD/PI：Toto，Robert D 总体：项目摘要/摘要 UT Southwestern的转化医学中心（CTM）是7个学术的合作 机构，5个医疗保健系统，6家教学医院和北德克萨斯社区。我们的使命是 到 通过创新和教育改善地方和全球社区的健康。 在过去的两个资金中 Cycles，我们的CTSA催化创新，并改变了我们计划中心的文化和景观。我们 已经培训了> 1,000名转化劳动力成员，共同领导了应计成立临床 试验CTSA网络并建立了新的翻译技术，方法和过程对 每个级别的翻译过程。我们很早就参与了当地社区的设计和行为 临床研究。我们还成立了新的合作研究服务以及教育和培训计划 旨在应对我们社区和国家的最大健康挑战。通过这些努力， CTM已经为推进了高度推动的转化科学发展了巨大的动力 协作环境是针对团队科学和社区参与的艰苦连接的。 在接下来的5年中，我们将优化CTSA中心的组织，以提高翻译 生物医学发现中的干预措施，最终将改善我们本地的健康状况 人口以及与CTSA网络合作的美国人口更广泛。我们会发现， 开发，演示和传播新的信息学和人工智能解决方案 各级翻译问题。与集线器合作伙伴和相关国家CTSA网络合作， 我们建议开发新的方法和过程，以进一步将研究整合到实践中 护理点。以我们的成功为基础，我们现在准备实现CTSA的五个关键目标 计划和转化医学中心，具有以下特定目的： 目标1。生产训练有素，高技能，多样化的翻译员工队伍。 目标2。灌输社区参与和团队科学。 目标3。将整个寿命的各种人群整合到临床和转化研究中。 目标4。促进创新和新的科学方法和过程。 目标5。开发创新的信息学解决方案来克服翻译障碍。 目标6。增加劳动力异质性。 影响：借助我们高度集成的动态研究和培训环境，我们的枢纽将有一个 对转化科学领域的强大而持续的影响。我们将在 临床和转化研究的范围，效率和质量，以使我们的枢纽和国家的利益 财团。我们将与领先的创新与协作中心合作，试用创新 网络和健康中心弥合科学发现与改善健康之间的差距。 项目摘要/摘要页面164 联系PD/PI：Toto，Robert D O.总体上：