Prediction of CVD Risk in Veterans

退伍军人心血管疾病风险预测

• 批准号: 8967209
• 负责人: Kelly Cho
• 金额: --
• 依托单位: VETERANS HEALTH ADMINISTRATION
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8967209
• 关键词: Address; Adult; Age; Algorithms; Assessment tool; Atherosclerosis; Atrial Fibrillation; Blood Platelets; Blood Pressure; Calibration; Cardiovascular Diseases; Cardiovascular system; Cessation of life; Cholesterol; Communities; Coronary artery; Coronary heart disease; Data; Development; Diabetes Mellitus; Diagnosis; Discrimination; Equation; Evaluation; Event; Formulation; Framingham Heart Study; Future; Glomerular Filtration Rate; Guidelines; Health; Health care facility; Health system; Heart failure; Hemoglobin; High Density Lipoprotein Cholesterol; High Prevalence; Lead; Lipids; Malignant Neoplasms; Mental Health; Mental disorders; Modeling; Morbidity - disease rate; Myocardial Infarction; Obesity; Outcome; Outpatients; Patient-Centered Care; Peripheral Vascular Diseases; Pharmaceutical Preparations; Population Group; Preventive service; Preventive therapy; Publishing; Race; Recording of previous events; Recurrence; Renal dialysis; Research; Resources; Risk; Risk Assessment; Risk Behaviors; Risk Estimate; Risk Factors; Role; Smoking; Stroke; Update; Veterans; Women' s Health; base; burden of illness; cardiovascular disorder risk; cardiovascular health; cigarette smoking; clinical care; clinical practice; cost; diabetes mellitus therapy; evidence base; experience; high risk; interest; mortality; personalized medicine; physical inactivity; pressure; sex

DESCRIPTION (provided by applicant): We propose to assess the role of cardiovascular disease (CVD) risk estimation in veterans without cancer or other major illnesses and compare the utility of using US national guideline estimates from ATP4 versus VA-specific formulations developed from VISN 1 and VISN 7. The core variables that will be used include traditional risk factors such age, sex, race, blood pressure, smoking, cholesterol, HDL cholesterol and diabetes status. In addition, we propose to identify the best ways to assess CVD risk in veterans with diabetes mellitus and in veterans who have already experienced a CVD event. We will evaluate the precision and accuracy of the ATP4 estimating equations in the VA and separately develop CVD risk equations using ATP4 variables to evaluate the best approach to estimate CVD risk in veterans. This critical evaluation of the risk of CVD in veterans is aimed to provide effective and convenient risk assessment tools - that in the future could be incorporated into clinical care for outpatient veterans and has the potential to guide CVD preventive therapy within the VA so that resources can be aligned to intervene appropriately with cardiovascular preventive services in veterans at high risk for developing a future CVD event. This proposal has direct relevance to the health risks of risky behavior (cigarette smoking), women's health, and patient-centered care.

描述（由申请人提供）： We propose to assess the role of cardiovascular disease (CVD) risk estimation in veterans without cancer or other major illnesses and compare the utility of using US national guideline estimates from ATP4 versus VA-specific formulations developed from VISN 1 and VISN 7. The core variables that will be used include traditional risk factors such age, sex, race, blood pressure, smoking, cholesterol, HDL cholesterol and diabetes status.此外，我们建议确定评估糖尿病退伍军人的CVD风险的最佳方法，以及已经经历过CVD事件的退伍军人。我们将评估VA中ATP4估计方程的精度和准确性，并使用ATP4变量分别开发CVD风险方程，以评估退伍军人中CVD风险的最佳方法。对退伍军人中CVD风险的这种批判性评估旨在提供有效且方便的风险评估工具 - 将来可以将其纳入门诊老兵的临床护理中，并有 在VA内指导CVD预防疗法的潜力，以便可以对资源保持一致，以适当地与退伍军人的心血管预防服务适当地进行开发未来CVD事件的高风险。该建议与风险行为（吸烟），妇女健康和以患者为中心的护理的健康风险直接相关。