Translational Research Activities in Neuropsychiatry (TRAIN)

神经精神病学转化研究活动（TRAIN）

基本信息

批准号：
9321772
负责人：
MADHUKAR H. TRIVEDI
金额：
$ 19.98万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-07-10 至 2019-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9321772
关键词：
Achievement Adaptive Behaviors Address Area Behavior Behavior Therapy Behavioral Biological Biology Clinical Clinical Research Cognition Coupled Department chair Development Doctor of Philosophy Education Electroencephalography Emerging Technologies Epigenetic Process Funding Future Genetic Genetic Research Goals Grant Heart Identity Crisis Institute of Medicine (U.S.)Institution Instruction Lead Leadership Medical center Medicine Mental Health Mental disorders Mentors Mentorship Mind National Institute of Mental Health Neurobiology Neurosciences Neurosciences Research Physicians Principal Investigator Proteomics Psychiatrist Psychiatry Recruitment Activity Research Research Activity Research Domain Criteria Research Infrastructure Research Personnel Research Training Residencies Resources Role Science Scientist Structure Students Technology Time Training Training Programs Translating Translational Research base career design faculty mentor leadership development medical schools medical specialties meetings neuroimaging neuropsychiatry next generation novel strategies optimism programs psychogenetics public health relevance skill acquisition success translational scientist trend

项目摘要

DESCRIPTION (provided by applicant): Advances in neuroscience, genetics, and the understanding of the biology of behavior have provided an opportunity to make profound advancements in understanding and treating mental illnesses. In order to take advantage of these advances, the next generation of researchers in psychiatry will need focused training that integrates translational research with clinical/behavioral training. While there is concern in the field of profound shortage of physician-scientists being trained (Yager et al., 2004; Fenton et al. 2004; "Psychiatry's Identity Crisis" 2012), there is also reason for optimism, in that the number of MD/PhD medical school graduates applying for psychiatric residencies has increased. Federal research monies have increased substantially to psychiatry departments over the last few decades, and yet, the percentage of psychiatrists with adequate research training, dedicated research time, and leadership roles (e.g., Principal Investigator) on funded grants lags well behind other areas of medicine (Kupfer et al., 2002). In order to address these needs, we are requesting support for the development of a translational clinical research training program. The Translational Research Activities In Clinical Neuroscience (TRAIN) program is designed to provide exceptional training and mentoring to psychiatry residents with the express goal of generating clinical and translational researchers in psychiatry who will go on to become independent physician-scientists. This program will focus on the relationship between disruptions in underlying genetics and neurobiology and how they relate to adaptive behavior, as in the NIMH Research Domain Criteria (RDoC) framework. This program will provide psychiatry residents training and mentorship from nationally recognized translational researchers in psychiatry. The program includes faculty mentors at UT Southwestern with active research programs, as well as meetings and instruction by nationally recognized researchers at other institutions. The program is also designed to reach out to students in training to recruit th best minds to become clinical researchers.

描述（由申请人提供）：神经科学，遗传学和对行为生物学的理解的进步为理解和治疗精神疾病做出了深远的进步。为了利用这些进步，精神病学领域的下一代研究人员将需要重点培训，将转化研究与临床/行为培训相结合。尽管在严重缺乏接受培训的医师科学家的情况下令人担忧（Yager等，2004； Fenton等，2004；“精神病学的身份危机” 2012年），但也有乐观的理由，因为MD/PHD医学院毕业生适用于精神病学居民。在过去的几十年中，联邦研究资金已大幅增加了精神病学部门，但是，通过足够的研究培训，专门的研究时间和领导职务（例如，首席研究人员）对资金赠款的延误远远落后于其他医学领域（Kupfer等人，2002年）的精神病医生的比例。为了满足这些需求，我们要求支持转化临床研究培训计划的发展。临床神经科学（TRAIN）计划的转化研究活动旨在为精神病学居民提供出色的培训和指导，其明确的目标是为精神病学领域的临床和转化研究人员提供，他们将继续成为独立的医师科学家。该计划将重点介绍基本遗传学和神经生物学中的破坏之间的关系，以及它们与适应性行为的关系，如NIMH研究领域标准（RDOC）框架。该计划将为精神病学居民提供精神病学转化研究人员的培训和指导。该计划包括UT西南大学的教师导师，并通过活跃的研究计划，以及其他机构的全国认可研究人员的会议和指导。该计划还旨在与学生接触培训，以招募最佳思想成为临床研究人员。