MHAS Cognitive Aging Ancillary Study

MHAS 认知老化辅助研究

基本信息

批准号：
9315063
负责人：
Rebeca Wong
金额：
$ 32.25万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-01 至 2020-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9315063
关键词：
Adult Aging Aging-Related Process Ancillary Study Archives Area Belief Biological Markers Childhood Cognition Cognitive aging Comparative Study Country Data Data Analyses Data Collection Data Sources Databases Dementia Developed Countries Developing Countries Elderly Family Family Study Fostering Funding Goals Health Health and Retirement Study Impaired cognition Individual Institution International Interview Interviewer Knowledge Latin America Latin American Lead Link Longitudinal Studies Measures Methodology Methods Mexican Mexico Parents Prevalence Procedures Protocols documentation Proxy Public Health Research Research Personnel Rest Risk Factors Sampling Sampling Studies Societies Structure Surveys Survivors Time Training United States United States National Institutes of Health Visit Walking aged aging population cognitive testing design experience field study knowledge base migration mortality outreach performance tests population based program dissemination public health relevance usability

项目摘要

DESCRIPTION (provided by applicant): The Mexican Health and Aging Study (MHAS) is a national longitudinal study of individuals aged 50 and older in Mexico, with three waves of data covering from 2001 to 2012, and wave-4 planned for 2015. Since its inception, the MHAS has been highly comparable to the Health and Retirement Study (HRS) in the United States, using similar protocols and survey contents. The overall goal of the proposed project is to assess the prevalence and risk factors of dementia and other cognitive impairments in Mexico with a harmonized approach, working with similar studies globally that use national samples and a population-based approach. The specific aims are: 1) Contribute to harmonization in the global study of dementia by launching an ancillary study of the national sample of older adults in Mexico, the MHAS. 2) Estimate the national prevalence of dementia and cognitive impairment in Mexico, harmonized with other countries, by using comparable data analysis strategies and methods. 3) Maximize the utilization of the MHAS data for cross-national dementia studies, by archiving, documenting, and disseminating the ancillary study databases and its resulting constructed variables. The ancillary study will include approximately 3,000 subjects, a sub-sample of the full MHAS wave-4 sample. The databases for the ancillary interview will include results from in-depth cognitive assessments and biomarkers, anthropometric measures, and performance tests. The harmonization goal will be achieved by collaborating with a `coordination project' conducted by researchers of the Health and Retirement Study (HRS) in the United States and through them, with the family of similar studies in the rest of the world. We will harmonize as much as possible, from the fieldwork training materials to the data cleaning, treatment of non-response, and methods used to cross-walk from the ancillary study to the full MHAS sample to estimate national prevalence of dementia and other cognitive impairments. The proposed ancillary study in Mexico will further enhance the analytical power of the parent study MHAS, enabling rigorous cross-national examination of the risk factors and consequences of dementia, an under- studied condition in developing countries that are aging rapidly.

描述（由申请人提供）：墨西哥健康与老龄化研究 (MHAS) 是一项针对墨西哥 50 岁及以上人群的全国纵向研究，数据涵盖 2001 年至 2012 年的三波数据，计划于 2015 年进行第四波数据。自成立以来，MHAS 与美国的健康与退休研究 (HRS) 具有高度可比性，使用相似的方案和调查内容。拟议项目的总体目标是：使用统一的方法评估墨西哥痴呆症和其他认知障碍的患病率和风险因素，并与使用国家样本和基于人群的方法的全球类似研究合作，具体目标是：1) 促进全球研究的协调一致。通过对墨西哥全国老年人样本开展辅助研究，MHAS 2) 通过使用可比较的数据分析策略和方法，与其他国家协调一致，估计墨西哥全国痴呆症和认知障碍的患病率。通过归档、记录和传播辅助研究数据库及其生成的变量，最大限度地利用 MHAS 数据进行跨国痴呆症研究。辅助研究将包括大约 3,000 名受试者，即完整 MHAS 波的子样本。 4 样本。辅助访谈的数据库将包括深入的认知评估和生物标记、人体测量和表现测试的结果。协调目标将通过以下方式实现。与美国健康与退休研究（HRS）研究人员开展的“协调项目”合作，并通过他们与世界其他地区的类似研究家族合作，我们将尽可能地与世界其他地区进行协调。现场工作培训材料，包括数据清理、无反应处理，以及从辅助研究到完整 MHAS 样本的交叉分析方法，以估计全国痴呆症和其他认知障碍的患病率。墨西哥的辅助研究将进一步增强母研究 MHAS 的分析能力，从而能够对痴呆症的风险因素和后果进行严格的跨国检查，痴呆症是快速老龄化的发展中国家的一种正在研究的疾病。