Midcareer Mentoring Award for Patient-Oriented Research in HIV and Cognition

艾滋病毒和认知领域以患者为导向的研究职业生涯中期指导奖

基本信息

批准号：
9187499
负责人：
VICTOR VALCOUR
金额：
$ 17.52万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-12-06 至 2017-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9187499
关键词：
Address Adult Age Aging Alzheimer&apos s Disease Anti-Retroviral Agents Archives Area Atrophic Autopsy Award Biological Brain Brain imaging Characteristics Clinical Research Cognition Cognitive Cognitive Science Communities Consensus Corpus Callosum Data Dementia Development Diagnosis Discipline Disease Elderly Enrollment Environment Epidemic Frequencies Funding Geriatrics Grant HIV Health Impaired cognition Impairment Individual Internal Medicine Investigation Link Measures Mentors Nature Neurodegenerative Disorders Neuroepidemiology Neurologic Neuropsychological Tests Older Population Outcome Patients Performance Pharmaceutical Preparations Population Proxy Publishing Research Research Personnel Risk San Francisco Science Site Social Network Social isolation Specimen Standardization Syndrome Testing Training Work career career development cerebral atrophy cohort design functional decline functional disability multidisciplinary neurobehavior neurobehavioral neuroimaging next generation patient oriented patient oriented research public health relevance success

项目摘要

DESCRIPTION (provided by applicant): HIV+ patients are aging, due in large part to the successes of combination antiretroviral medications. Despite these accomplishments, over 50% of community dwelling HIV+ patients have cognitive impairment, a frequency that increases with age. The candidate of this application has developed a robust clinical research environment to address brain vulnerability in the setting of HIV. His training in internal medicine, geriatric medicine and neurobehavior allow him to link disciplines and inform the cognitive consequences of aging with HIV. The work proposed in this application will enhance and stabilize his career development to focus more directly on training the next generation of high quality patient-oriented researchers. The proposed science will focus on the functional consequence of cognitive impairment in HIV over age 60 and the co-existence of geriatric syndromes. Unique features of the mentoring plan include access to networks of patients, a passion for training early-stage investigators, and the multi-disciplinary training of the candidate.

描述（由申请人提供）：HIV+患者正在衰老，这在很大程度上是由于联合抗逆转录病毒药物的成功。尽管取得了这些成就，超过50％的社区住宅HIV+患者具有认知障碍，这种频率随着年龄的增长而增加。该应用程序的候选人已经开发了一种强大的临床研究环境，以解决艾滋病毒中大脑脆弱性。他在内科，老年医学和神经行为方面的培训使他能够将学科联系起来，并为艾滋病毒的衰老带来认知后果。本应用程序中提出的工作将增强和稳定他的职业发展，更加直接地专注于培训下一代高质量的以患者为导向的研究人员。拟议的科学将重点关注60岁以上HIV认知障碍的功能后果以及老年综合征的共存。指导计划的独特功能包括访问患者网络，对培训早期调查人员的热情以及对候选人的多学科培训。