Multidisciplinary K12 Urologic Research (KURe) Career Development Program

多学科 K12 泌尿学研究 (KURe) 职业发展计划

• 批准号: 9325500
• 负责人: Dolores Jean Lamb
• 金额: --
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9325500
• 关键词: Alpha Cell; Area; Basic Science; Biology; Cell Cycle Regulation; Cellular biology; Childhood; Defect; Development; Doctor of Medicine; Doctor of Philosophy; Ensure; Environment; Faculty; Funding; Genetic; Genitourinary system; Genomics; Goals; Medicine; Mentors; Minority; Pathology; Peer Review; Physicians; Program Development; Recruitment Activity; Reproductive Health; Reproductive Medicine; Research; Research Personnel; Research Training; SECTM1 gene; Scientist; Stem cells; Structure; Teacher Professional Development; Training; Translational Research; United States National Institutes of Health; Urology; Woman; Work; career development; clinical translation; college; experience; gene therapy; lower urinary tract symptoms; male; male health; member; men; multidisciplinary; programs; reproductive tract; steroid hormone; steroid hormone receptor; strength training; urologic

DESCRIPTION (provided by applicant): This application seeks support for our competing renewal application for the Multidisciplinary K12 Urologic Research (KURe) Career Development Program to the Scott Department of Urology and the Center for Reproductive Medicine at Baylor College of Medicine. The research emphasis of this program is in the areas pediatric urology/genitourinary development, steroid hormone action, stem cells genetics and lower urinary tract symptoms (LUTS). The training faculty includes 7 Ph.D/M.D., Ph.D. faculty and11 M.D.s. Dr. Lamb will serve as both the Program Director and the Administrative Director of the KURe career development program. Dr. Boone will serve as co-Director. Drs. Lipshultz, Cunningham, Gonzales, Khera, Roth, Janzen will ensure the M.D. trainees are optimally trained in the urologic subspecialty areas of men's health and pediatric urology. The major research areas in the program include: genetics and genomics of genitourinary developmental defects, cell biology, steroid hormone receptors, male reproductive tract biology, genetics, cell cycle control, stem cells, gene therapy and LUTS. The trainees will be M.D. and Ph.D. junior faculty members at Baylor College of Medicine. Our program attracts highly qualified trainees who seek intensive and substantial research training in urology research with an emphasis on clinical translation. We have a defined recruitment plan that emphasizes the recruitment of women and minorities. The strengths of the training environment include highly respected, well-funded, experienced faculty, the high ranking national ranking for NIH funding of a Urology/Cell Biology/Genetics/Pathology departments, a structured mentoring program with required coursework, a cell biology graduate program with relevant course work and depth in both cell biology and genetics. Most importantly, we have a strong track record of training successful physician scientists. Our long- term goal is to train these young investigators to successfully compete for peer-reviewed funding and eventually to increase basic and translational research efforts in men's reproductive health research.

描述（由申请人提供）：本申请为我们在贝勒医学院的Scott泌尿外科和生殖医学中心的多学科K12泌尿外科研究（KURE）职业发展计划中寻求支持。该计划的研究重点是小儿泌尿外科/泌尿生殖学发展，类固醇激素作用，干细胞遗传学和较低的尿路症状（LUTS）。培训学院包括7博士/M.D.，博士学位。教师和11 M.D.S. Lamb博士将担任计划主任和Kure职业发展计划的行政总监。 Boone博士将担任联合导演。博士。 Lipshultz，Cunningham，Gonzales，Khera，Roth，Janzen将确保在男性健康和儿科泌尿科的泌尿外科亚科领域对医学博士的学员进行最佳培训。该计划的主要研究领域包括：遗传学和基因组学的发育缺陷，细胞生物学，类固醇激素受体，雄性生殖道生物学，遗传学，细胞周期控制，干细胞，基因治疗，基因治疗和LUTS。学员将是医学博士和博士学位。贝勒医学院的初级教师。我们的计划吸引了高素质的学员，他们寻求泌尿外科研究的深入研究培训，重点是临床翻译。我们制定了一个明确的招聘计划，该计划强调了妇女和少数民族的招募。训练环境的优势包括高度尊重，资金丰富，经验丰富的教师，NIH资助的高级国家排名泌尿外科/细胞生物学/遗传学/病理学部门，这是一个带有必需课程的结构化指导计划，具有细胞生物学研究生课程，具有细胞生物学和遗传学的相关课程工作。最重要的是，我们在培训成功的医师科学家方面有很强的记录。我们的长期目标是培训这些年轻的调查人员，以成功地争夺经过同行评审的资金，并最终增加男性生殖健康研究中的基本和转化研究工作。

项目成果

Distribution of Semen Parameters Among Adolescent Males Undergoing Fertility Preservation in a Multicenter International Cohort.

多中心国际队列中接受生育力保存的青少年男性精液参数的分布。

• DOI: 10.1016/j.urology.2019.01.027
• 发表时间: 2019
• 期刊: Urology
• 影响因子: 2.1
• 作者: Halpern,JoshuaA;Thirumavalavan,Nannan;Kohn,TaylorP;Patel,AmirS;Leong,JoonYau;Cervellione,RaimondoM;Keene,DavidJB;Ibrahim,Emad;Brackett,NancyL;Lamb,DoloresJ;Ramasamy,Ranjith
• 通讯作者: Ramasamy,Ranjith

Rear Tip Extenders and Penile Prosthesis Rigidity: A Laboratory Study of Coloplast Prostheses.

后尖延长器和阴茎假体刚性：康乐保假体的实验室研究。

• DOI: 10.1016/j.jsxm.2018.05.001
• 发表时间: 2018
• 期刊: The journal of sexual medicine
• 作者: Thirumavalavan,Nannan;Cordon,BillyH;Gross,MartinS;Taylor,Jeffrey;Eid,Jean-Francois
• 通讯作者: Eid,Jean-Francois

Efficacy and Safety of Common Ingredients in Aphrodisiacs Used for Erectile Dysfunction: A Review.

用于治疗勃起功能障碍的春药中常见成分的功效和安全性：综述。

• DOI: 10.1016/j.sxmr.2020.01.001
• 发表时间: 2020
• 期刊: Sexual medicine reviews
• 影响因子: 3.6
• 作者: Srivatsav,Ashwin;Balasubramanian,Adithya;Pathak,UjvalIshu;Rivera-Mirabal,Jorge;Thirumavalavan,Nannan;Hotaling,JamesM;Lipshultz,LarryI;Pastuszak,AlexanderW
• 通讯作者: Pastuszak,AlexanderW

Complex rectovaginal fistulas after pelvic organ prolapse repair with synthetic mesh: a multidisciplinary approach to evaluation and management.

用合成网修复盆腔器官脱垂后的复杂直肠阴道瘘：一种多学科的评估和管理方法。

• DOI: 10.1097/spv.0b013e318270ae15
• 发表时间: 2012
• 期刊: Female pelvic medicine & reconstructive surgery
• 影响因子: 1.6
• 作者: Choi,JudyM;Nguyen,Vian;Khavari,Rose;Reeves,Keith;Snyder,Michael;Fletcher,SophieG
• 通讯作者: Fletcher,SophieG

Racial differences in sexual dysfunction among postdeployed Iraq and Afghanistan veterans.

• DOI: 10.1177/1557988312471842
• 发表时间: 2013-09
• 期刊: American journal of men's health
• 作者: Hosain GM;Latini DM;Kauth MR;Goltz HH;Helmer DA
• 通讯作者: Helmer DA