HEY: Hispanic Eye Study

嘿：西班牙裔眼睛研究

• 批准号: 9614750
• 负责人: Lama A Al-Aswad
• 金额: $ 18.75万
• 依托单位: UNIVERSITY OF TEXAS RIO GRANDE VALLEY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9614750
• 关键词: Academic Medical Centers; Achievement; Address; Adherence; Affect; African American; Age; Age related macular degeneration; Aging; Area; Behavioral; Belief; Blindness; Caribbean region; Caring; Chronic; Chronic Disease; Communities; Community Health Aides; Community Outreach; Complex; Coupled; Data; Detection; Deterioration; Development; Diabetic Retinopathy; Diagnosis; Diagnostic; Disease; Early Diagnosis; Early treatment; Elderly; Epidemiology; Equipment; Ethnic Origin; Ethnic group; Exhibits; Eye; Eye diseases; Focus Groups; Fright; Future; Glaucoma; Head; Health; Health Services Accessibility; Healthcare; High Prevalence; Hispanic Americans; Hispanics; Improve Access; Individual; Injury; Intervention; Knowledge; Latin America; Lead; Longevity; Medical; Medical center; Modeling; New York; Ophthalmologist; Ophthalmology; Participant; Pilot Projects; Population; Population Sciences; Prevalence; Prevention; Protocols documentation; Qualitative Research; Quality of life; Recommendation; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Societies; Standardization; Statistical Data Interpretation; Target Populations; Testing; Texas; Training; United States National Institutes of Health; Universities; Venezuela; Visual; Visual impairment; Woman; analytic epidemiology; base; cost; cost effective; design; diabetic; diabetic cataract; economic cost; evidence base; experience; follow-up; gene environment interaction; high risk; implementation research; implementation science; improved; member; prevent; programs; response; retinal imaging; retinal nerve fiber layer; screening; social

SUMMARY Blindness is a top health fear across ethnic groups and populations worldwide. Severe vision loss in middle and old age constitutes a personal crisis for individuals, with important social and economic costs to society. Hispanics are disproportionally affected by 3 leading noncommunicable disease (NCD) causes of blindness – glaucoma, diabetic retinopathy and cataracts – but development and implementation of interventions that can facilitate identification, follow-up and treatment of individuals at high risk of blindness to reduce blindness and moderate-to-severe visual impairment (MSVI) in such populations remains preliminary and inadequate. Screening of individuals at high risk but without functional visual loss and early case-detection can significantly improve prevention of blindness and MSVI, when coupled with appropriate treatment and support. Besides cost of equipment, implementation of such interventions in LAC is limited by 1) cultural beliefs toward blindness and visual impairment in middle and older ages, and gaps in our understanding thereof; and 2) lack of readily available standardized, culturally sensitive protocols that are practical and adaptable to use in diverse settings of LAC, targeting populations at high risk, such as those residing in regions of poor health care access and high NCD rates. The purpose of this exploratory-developmental project is to begin to overcome these barriers by developing and pilot-testing the Hispanic Eye (HEY) study, a community-based intervention that focuses on improving access to eye health care in Venezuela (VZ), where our established research and capacity-building infrastructure will allow us to accomplish the following specific aims: Aim 1. To assess social, behavioral, cultural and structural factors that impact screening and early case detection of leading causes of blindness, as well as adherence to follow-up recommendations to inform development and initiation of a plan to promote the design and implementation of a community-based program to improve efforts to prevent, detect early and provide appropriate treatments in VZ. Aim 2. To test feasibility, acceptability and efficacy of the Hispanic Eye (HEY) study in VZ we will develop, implement and assess a pilot study with 350 high-risk residents of Santa Lucía and Santa Rosa communities in Maracaibo VZ. To achieve these aims, our team encompasses expert scientists extensively experienced in population science, ophthalmology, analytical epidemiology, implementation science, and VZ populations. The results will generate preliminary data needed to justify a full R01 collaborative study, and identify specific research questions show the greatest promise to advance prevention of visual loss in Hispanics, and provide critical new knowledge to facilitate widespread implementation, dissemination and sustained application of evidence-based eye care strategies in LAC and in high-risk U.S. populations.

概括 失明是全球各族裔和人群中最令人担忧的健康问题，严重视力丧失。 老年对个人构成个人危机，给社会带来重大的社会和经济成本。 西班牙裔人受到导致失明的 3 种主要非传染性疾病 (NCD) 的影响尤为严重 – 青光眼、糖尿病性视网膜病变和白内障——但制定和实施干预措施可以 促进失明高危人群的识别、随访和治疗，以减少失明和 对此类人群的中度至重度视力障碍（MSVI）的研究仍处于初步阶段且不够充分。 对高危但无功能性视力丧失的个体进行筛查以及早期病例发现可以显着 结合适当的治疗和支持，可以改善失明和 MSVI 的预防。 设备成本，在 LAC 实施此类干预措施受到以下因素的限制：1) 对失明的文化信仰 中老年人的视力障碍以及我们对此的理解存在差距；2）缺乏及时性； 可用的标准化、文化敏感协议，实用且适合在不同环境中使用 拉丁美洲和加勒比地区，针对高风险人群，例如居住在医疗保健条件较差地区的人群 非传染性疾病发病率高。 这个探索性开发项目的目的是通过开发来开始克服这些障碍 并试点测试西班牙裔眼睛 (HEY) 研究，这是一项基于社区的干预措施，重点是改善 在委内瑞拉 (VZ) 获得眼保健服务，我们在那里建立了研究和能力建设 基础设施将使我们能够实现以下具体目标： 目标 1. 评估社会、行为、 影响失明主要原因筛查和早期病例发现的文化和结构因素，如 以及遵守后续建议，为制定和启动促进计划提供信息 设计和实施基于社区的计划，以改进预防、早期发现和预防的努力 目标 2. 测试西班牙眼病的可行性、可接受性和有效性。 （嘿）在 VZ 的研究中，我们将针对圣诞老人的 350 名高风险居民开发、实施和评估一项试点研究 马拉开波 VZ 的圣卢西亚和圣罗莎社区 为了实现这些目标，我们的团队包括专家。 科学家主要在人口科学、眼科学、分析流行病学、 实施科学和 VZ 群体的结果将生成证明完整合理性所需的初步数据。 R01 合作研究，并确定具体的研究问题，显示出最大的进步前景 预防西班牙裔视力丧失，并提供重要的新知识以促进广泛 在拉丁美洲和加勒比地区和其他国家实施、传播和持续应用循证眼保健策略 美国高危人群。