HEY: Hispanic Eye Study

嘿：西班牙裔眼睛研究

• 批准号: 9614750
• 负责人: Lama A Al-Aswad
• 金额: $ 18.75万
• 依托单位: UNIVERSITY OF TEXAS RIO GRANDE VALLEY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2020-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9614750
• 关键词: Academic Medical Centers; Achievement; Address; Adherence; Affect; African American; Age; Age related macular degeneration; Aging; Area; Behavioral; Belief; Blindness; Caribbean region; Caring; Chronic; Chronic Disease; Communities; Community Health Aides; Community Outreach; Complex; Coupled; Data; Detection; Deterioration; Development; Diabetic Retinopathy; Diagnosis; Diagnostic; Disease; Early Diagnosis; Early treatment; Elderly; Epidemiology; Equipment; Ethnic Origin; Ethnic group; Exhibits; Eye; Eye diseases; Focus Groups; Fright; Future; Glaucoma; Head; Health; Health Services Accessibility; Healthcare; High Prevalence; Hispanic Americans; Hispanics; Improve Access; Individual; Injury; Intervention; Knowledge; Latin America; Lead; Longevity; Medical; Medical center; Modeling; New York; Ophthalmologist; Ophthalmology; Participant; Pilot Projects; Population; Population Sciences; Prevalence; Prevention; Protocols documentation; Qualitative Research; Quality of life; Recommendation; Research; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Societies; Standardization; Statistical Data Interpretation; Target Populations; Testing; Texas; Training; United States National Institutes of Health; Universities; Venezuela; Visual; Visual impairment; Woman; analytic epidemiology; base; cost; cost effective; design; diabetic; diabetic cataract; economic cost; evidence base; experience; follow-up; gene environment interaction; high risk; implementation research; implementation science; improved; member; prevent; programs; response; retinal imaging; retinal nerve fiber layer; screening; social

SUMMARY Blindness is a top health fear across ethnic groups and populations worldwide. Severe vision loss in middle and old age constitutes a personal crisis for individuals, with important social and economic costs to society. Hispanics are disproportionally affected by 3 leading noncommunicable disease (NCD) causes of blindness – glaucoma, diabetic retinopathy and cataracts – but development and implementation of interventions that can facilitate identification, follow-up and treatment of individuals at high risk of blindness to reduce blindness and moderate-to-severe visual impairment (MSVI) in such populations remains preliminary and inadequate. Screening of individuals at high risk but without functional visual loss and early case-detection can significantly improve prevention of blindness and MSVI, when coupled with appropriate treatment and support. Besides cost of equipment, implementation of such interventions in LAC is limited by 1) cultural beliefs toward blindness and visual impairment in middle and older ages, and gaps in our understanding thereof; and 2) lack of readily available standardized, culturally sensitive protocols that are practical and adaptable to use in diverse settings of LAC, targeting populations at high risk, such as those residing in regions of poor health care access and high NCD rates. The purpose of this exploratory-developmental project is to begin to overcome these barriers by developing and pilot-testing the Hispanic Eye (HEY) study, a community-based intervention that focuses on improving access to eye health care in Venezuela (VZ), where our established research and capacity-building infrastructure will allow us to accomplish the following specific aims: Aim 1. To assess social, behavioral, cultural and structural factors that impact screening and early case detection of leading causes of blindness, as well as adherence to follow-up recommendations to inform development and initiation of a plan to promote the design and implementation of a community-based program to improve efforts to prevent, detect early and provide appropriate treatments in VZ. Aim 2. To test feasibility, acceptability and efficacy of the Hispanic Eye (HEY) study in VZ we will develop, implement and assess a pilot study with 350 high-risk residents of Santa Lucía and Santa Rosa communities in Maracaibo VZ. To achieve these aims, our team encompasses expert scientists extensively experienced in population science, ophthalmology, analytical epidemiology, implementation science, and VZ populations. The results will generate preliminary data needed to justify a full R01 collaborative study, and identify specific research questions show the greatest promise to advance prevention of visual loss in Hispanics, and provide critical new knowledge to facilitate widespread implementation, dissemination and sustained application of evidence-based eye care strategies in LAC and in high-risk U.S. populations.

概括 失明是全球范围内的最高健康恐惧。中间的严重视力丧失 老年对个人构成了个人危机，对社会的社会和经济成本重要。 西班牙裔受到3种领先的非通信疾病（NCD）的影响不成比例的影响 - 青光眼，糖尿病性视网膜病和白内障 - 但可以开发和实施干预措施 促进对处于高失明风险的个人的识别，随访和治疗，以减少失明和 此类人群中的中度至重度视觉障碍（MSVI）仍然是初步的和不足的。 筛选处于高风险的个体，但没有功能性视觉丧失和早期案例检测可以显着 加上适当的治疗和支持时，改善了失明和MSVI的预防。除了 设备成本，在LAC中实施此类干预措施受到1）对失明的文化信念的限制 和年龄段的视觉障碍，以及我们的理解差距； 2）缺乏容易的 可用的标准化，具有文化敏感的协议，可实用且可适应于潜水员环境 LAC的针对人群高风险，例如居住在医疗保健不良地区和 高NCD率。 这个探索性开发项目的目的是开始克服这些障碍 以及对西班牙裔眼睛（HEY）研究的试点测试，这是一种基于社区的干预措施，侧重于改进 委内瑞拉（VZ）获得眼保健，我们既定的研究和能力建设 基础架构将使我们能够完成以下特定目标：目标1。评估社会，行为， 影响筛查和早期病例检测失明原因的文化和结构因素，作为 以及遵守后续建议，以告知开发和主动性，以促进该计划 设计和实施基于社区的计划，以改善努力，以预防，检测早期和 在VZ中提供适当的治疗方法。目标2。测试西班牙裔眼睛的可行性，可接受性和效率 （嘿）在VZ中的研究，我们将与350名圣诞老人的高危居民开发，实施和评估一项试点研究 Maracaibo VZ的Lucía和Santa Rosa社区。为了实现这些目标，我们的团队包括专家 科学家在人口科学，眼科，分析流行病学方面有丰富的经验， 实施科学和VZ人群。结果将生成所需的初步数据，以证明完整的合理性 R01协作研究并确定特定的研究问题表明，前进的最大希望 预防西班牙裔视觉丧失，并提供关键的新知识以促进宽度 在LAC和 美国高风险人口。