Philadelphia HIV Therapeutics and Prevention Clinical Trials Unit

费城艾滋病毒治疗和预防临床试验单位

基本信息

批准号：
8609631
负责人：
Ian Frank
金额：
$ 206.38万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-02-01 至 2020-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8609631
关键词：
AIDS clinical trial group AIDS prevention Adherence Adolescent Adult Advertising Affect Ancillary Study Behavioral Research Biology Bone Diseases Cardiovascular Diseases Caring Child Childhood Clinical Trials Clinical Trials Unit Communities Community Health Education Conduct Clinical Trials Consequences of HIV Data Drug Evaluation Epidemic Evaluation Faculty Functional disorder Future Goals HIV HIV Infections HIV Vaccine Trials Network HIV therapy HIV vaccine Hepatitis B Hepatitis C virus Heterosexuals Host resistance Human Papillomavirus Human immunodeficiency virus test IMPAACT Immune Infection Control Kidney Diseases Leadership Link Malignant Neoplasms Medical Medicine Mentors Neurocognitive New Agents Pathogenesis Pediatric Hospitals Pennsylvania Philadelphia Population Pregnant Women Prevention Prevention strategy Prophylactic treatment Protocols documentation Recovery Recruitment Activity Research Research Infrastructure Research Personnel Resistance Science Site Specimen Structure Testing Therapeutic Therapy Clinical Trials Training Tuberculosis Universities Vaccines Vertical Disease Transmission Virus Work antiretroviral therapy clinical research site college cost efficient gene therapy immune activation immune function improved innovation intravenous drug user medical schools men who have sex with men microbicide next generation novel outreach prevent prevention clinical trial protocol development purge rectal microbicide senescence symposium transgender treatment strategy vaginal microbicide working group

项目摘要

DESCRIPTION (provided by applicant): The Philadelphia HIV Therapeutic and Prevention Clinical Trials Unit (Philadelphia HIV CTU-PHCTU) will provide the administrative infrastructure and scientific leadership to advance the science of HIV treatment and prevention within the five proposed HIV Research Networks, Adult Therapeutics, Therapeutics in Pediatric and Maternal Populations, Integrated Prevention, Vaccines, and Microbicides through four specific research aims: Specific Aim 1. Participate in the creation and implementation of the scientific agenda of the HIV Research Networks through committee and protocol team membership and through initiation of new Network science. Specific Aim 2. Participate in the implementation of the scientific agenda of the HIV Research Networks through the cost efficient conduct of clinical trials. Specific Aim 3. Train and mentor the next generation of HIV investigators. By engaging fellows and junior faculty in protocol development, educational conferences and clinical trials, the PHCTU will actively recruit and train the next generation of HIV investigators. Specific Aim 4. Educate the Philadelphia medical, scientific and HIV-affected communities about advances in HIV therapy and prevention. The Philadelphia HIV CTU will help to coordinate and advertise the HIV-related medical and scientific forums that currently exist, and will continue to seek input from the HIV-affected community through its Community Advisory Board and through educational outreach to HIV affected groups. The Philadelphia HIV CTU will feature an integrated, efficient clinical trials structure with four clinical research sites, three on the University of Pennsylvania (University of Pennsylvania Perelman School of Medicine-PSOM and The Children's Hospital of Philadelphia- CHOP) medical campus and one on the Drexel University medical campus, including two sites that will focus on adult HIV therapeutic trials, one that will focus on adult prevention trials, and one that will focus on trials involving pediatric ad adolescent populations.

描述（由申请人提供）：费城HIV治疗和预防临床试验部（费城HIV HIV CTU-PHCTU）将提供行政基础设施和科学领导力，以推动五个提议的HIV HIV研究网络，成人治疗，成人治疗，培养精神，整合培训，整合培训的培训，并在五个提议的hiv科学上进行艾滋病毒治疗和预防科学。研究目的：特定目的1。通过委员会和协议团队成员身份以及启动新网络科学来参与艾滋病毒研究网络的科学议程的创建和实施。具体目标2。通过临床试验的经济高效行为，参与艾滋病毒研究网络的科学议程的实施。特定目标3。训练和指导下一代艾滋病毒调查人员。通过让研究员和初级教师参与协议发展，教育会议和临床试验，PHCTU将积极招募和培训下一代HIV研究者。特定目的4。教育费城医学，科学和受艾滋病毒影响的社区有关艾滋病毒治疗和预防的进步。费城HIV CTU将有助于协调和宣传当前存在的与HIV相关的医学和科学论坛，并将通过其社区顾问委员会以及通过对HIV受影响的群体向受HIV影响的社区寻求意见。费城HIV CTU将具有四个临床研究地点的集成，有效的临床试验结构，在宾夕法尼亚大学（宾夕法尼亚大学Perelman大学医学院PSOM学校和费城 - CHOP- CHOP- CHOP）的儿童医院的三个临床研究网站上，其中一个是Drexel University Comperiation the Drexel University Campus，其中包括Drexel University Campus，其中包括在内这将着重于成人预防试验，并将重点放在涉及小儿AD青少年人群的试验上。