The Role of Perturbed Auditory Information for Self-motion in Gait

扰动听觉信息对步态中自我运动的作用

• 批准号: 10891772
• 负责人: Dobromir Dotov
• 金额: $ 16.15万
• 依托单位: UNIVERSITY OF NEBRASKA OMAHA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10891772
• 关键词: Activities of Daily Living; Address; Adult; Area; Attention; Auditory; Auditory system; Brain imaging; Cognitive; Control Groups; Coupling; Disease; Elderly; Electroencephalography; Event; Exhibits; Feedback; Gait; Individual; Measures; Motion; Motor; Movement; Participant; Persons; Phase; Role; Sensory; Stimulus; System; Testing; Time; Training; Visit; Walking; Work; cognitive system; falls; functional near infrared spectroscopy; gait rehabilitation; hearing impairment; improved; instrument; prevent; response; sound; success; treadmill; virtual reality; young adult

When people interact with objects such as opening a door, their movements make sounds that are associated with the success of the action. Similarly, when people walk their footsteps make sounds that are audible. It is possible that these sounds are used as feedback to stabilize and adapt movement. There is some evidence for such a connection between the auditory and motor systems in activities of daily living, yet the empirical work is insufficient and indirect. The objective of the project is to address this gap by investigating the functional connection between gait dynamics and stepping sounds. In each of the three proposed studies, the delay and amplitude of self-produced footstep sounds will be manipulated while young healthy adults are performing a self-paced treadmill walking task. To this end, a gait real-time analysis interactive lab will be programmed. The apparatus consists of an instrumented treadmill and virtual reality sound projection capability. The overall hypothesis is that walking cadence will change proportionally to the magnitude and sign of the manipulation of footstep sounds. Furthermore, the statistical persistence of inter-step intervals will decrease as a function of feedback alteration. Next to these motor responses, the proposed project will investigate associated cortical responses by using mobile brain imaging. One study will use fNIRS to focus on measures associated with attentional demand. A second study will use a combination of mobile EEG and EMG to investigate cortico-spinal synchronization. The third study will evaluate whether repetitive sessions of so-called stealth walking hold potential for improving gait dynamics and variability. The study will involve five visits to the lab. Participants’ task will be to step so as to minimize the otherwise augmented feedback from the their footstep sounds. Change in gait parameters from pre- to post-training will be compared to a control group.

当人们与物体互动（例如开门）时，他们的动作会发出声音 同样，当人们行走时，他们的脚步发出的声音与行动的成功相关。 这些声音可能被用作稳定和适应运动的反馈。 有证据表明日常活动中听觉系统和运动系统之间存在这种联系 该项目的目标是解决这一差距。 通过研究每个步态动力学和踏步声音之间的功能联系。 三项拟议的研究，将操纵自行产生的脚步声的延迟和脚步幅度 而年轻健康的成年人正在执行自定进度的跑步机步行任务，为此，实时步态。 分析交互式实验室将被编程。该设备由仪器化跑步机和 虚拟现实声音投射能力的总体假设是步行节奏会改变。 与脚步声操纵的幅度和符号成正比。 步骤间的统计持久性将随着反馈间隔的变化而降低。 这些运动反应，拟议的项目将通过使用调查相关的皮质反应 一项研究将使用 fNIRS 来关注与注意力需求相关的测量。 第二项研究将结合使用移动脑电图和肌电图来研究皮质脊髓 第三项研究将评估所谓的“隐形行走”的重复训练是否有效。 该研究将涉及五次实验室访问。 参与者的任务是尽量减少来自他们的反馈，否则会增加反馈。 训练前和训练后的步态参数变化将与对照组进行比较。