Acquisition of a Nano Computed Tomography Instrument for shared Cornell Imaging f

购买纳米计算机断层扫描仪用于共享康奈尔成像 f

基本信息

批准号：
8333738
负责人：
Christopher John Hernandez
金额：
$ 75.47万
依托单位：
CORNELL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2013
资助国家：
美国
起止时间：
2013-04-20 至 2014-04-19
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): This is a request for funds for an Xradia VersaXRM-500 micro- and nano-computed tomography instrument. The requested instrument will expand the Cornell Micro-CT facility from in vivo scanning (25 micrometer resolution) to in vitro scanning (0.56 micrometer resolution) to meet the medical research needs of 10 principal investigators with NIH funding. The new instrument will be located within and managed by the Cornell University Microscopy and Imaging Facility, whose main focus is to support imaging needs on campus and in central New York. The Microscopy and Imaging Facility is located within the newly built, $160 million Weill Hall facility that was designed to the be the hub for Cornell's New Life Sciences Initiative. The Xradia VersaXRM- 500 device has novel capabilities including sub-micron resolution in specimens larger than 4mm in size and phase contrast enhanced computed tomography allowing visualization and assessment of soft tissues with or without contrast agents. The instrument will directly enhance the research needs of 9 major users, each of whom have found that existing imaging approaches are not sufficient for their current and future needs. The device will be used immediately to enhance research on a) the development and treatment of osteoporosis and other defects in bone; b) treatment of osteoarthritis; c) the development of lung cancer; e) uterine pre- eclampsia; d) congenital defects in the heart and will be used in future investigations on these health topics and others.

描述（由申请人提供）：这是Xradia Versaxrm-500微型和纳米计算的层析成像仪器的资金请求。请求的仪器将将康奈尔微型CT设施从体内扫描（25千分尺）扩展到体外扫描（0.56千分尺），以满足10位拥有NIH资金的主要研究人员的医学研究需求。新乐器将位于康奈尔大学显微镜和成像设施内部并管理，其主要重点是支持校园和纽约中部的成像需求。显微镜和成像设施位于新建的，1.6亿美元的Weill Hall设施中生命科学计划。 Xradia versaxrm-500设备具有新的功能，包括大于4mm的标本中的亚微米分辨率，相对造影剂增强了计算机断层扫描，可视化和评估具有或没有对比剂的软组织。该仪器将直接提高9个主要用户的研究需求，每个人都发现现有的成像方法不足以满足其当前和未来需求。该设备将立即用于增强对a）骨质疏松症和骨骼其他缺陷的发展和治疗； b）治疗骨关节炎； c）肺癌的发展； e）子宫前倾斜度； d）心脏中的先天性缺陷，将在未来对这些健康主题和其他主题的调查中使用。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Experimental and computational understanding of pulsatile release mechanism from biodegradable core-shell microparticles.

DOI：
10.1126/sciadv.abn5315
发表时间：
2022-07-15
期刊：
Science advances
影响因子：
13.6
作者：
通讯作者：

Oceanic intraplate explosive eruptions fed directly from the mantle

海洋板内爆炸性喷发直接来自地幔

DOI：
10.1073/pnas.2302093120
发表时间：
2023
期刊：
Proceedings of the National Academy of Sciences
影响因子：
0
作者：
DeVitre, Charlotte L.;Gazel, Esteban;Ramalho, Ricardo S.;Venugopal, Swetha;Steele-MacInnis, Matthew;Hua, Junlin;Allison, Chelsea M.;Moore, Lowell R.;Carracedo, Juan Carlos;Monteleone, Brian
通讯作者：
Monteleone, Brian

Shark teeth as edged weapons: serrated teeth of three species of selachians.

作为利器的鲨鱼牙齿：三种鲨鱼的锯齿状牙齿。