Animal Holding Area Expansion in Support of AIDS-Related Research at the WaNPRC

扩大动物饲养区以支持 WaNPRC 的艾滋病相关研究

• 批准号: 8658202
• 负责人: Michael J Mustari
• 金额: $ 99.91万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2017-06-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8658202
• 关键词: Acquired Immunodeficiency Syndrome; Animal Housing; Animals; Area; Biomedical Research; Commit; Complement; Containment; Funding; Housing; Operative Surgical Procedures; Primates; Recommendation; Research; Research Personnel; Research Project Grants; Subfamily lentivirinae; Universities; Washington; design; guide for the care and use of laboratory animals; improved; nonhuman primate; programs; square foot

The Washington National Primate Research Center (WaNPRC) has supported AIDS-related research projects for more than 25 years. These projects are performed at the Western facility, where the vivarium is designed to house nonhuman primates at an ABSL-2 containment level with enhanced containment practices implemented for lentivirus research. The AIDS-related research program is expanding with the addition of new core staff, funding of new projects for existing core staff, and new collaborative efforts between core staff and external investigators. With a projected increase in animal numbers, a need to upgrade cage wash facilities, and a need to expand surgical capabilities for upcoming projects, the University of Washington has committed $5.6 million to expand the vivarium by approximately 2500 square feet at the WaNPRC Western facility, install a new cage-wash/autoclave facility and build a state-of-the-art surgical suite for the support of AIDS-related research. We are requesting additional funding to convert the current surgical area into animal housing and to build out additional area within the expanded vivarium space for animal holding. The proposed animal holding rooms will accommodate 80 Group four (10-15 kg) nonhuman primates, or more smaller animals. The rooms will be constructed in accordance with the recommendations of the eighth edition of the Guide for the Care and Use of Laboratory Animals. The completion of the animal holding space will synergistically complement the institutionally-funded project to upgrade the cage-wash facilities and surgical suite, and will improve and increase our ability to conduct biomedical research, especially AIDS-related research.

华盛顿国家灵长类动物研究中心（WANPRC）已支持与艾滋病相关的研究项目超过25年。这些项目是在西方工厂进行的，该工厂旨在将非人类灵长类动物设置为ABSL-2遏制水平，并为慢病毒研究实施了增强的遏制实践。与AIDS相关的研究计划正在扩大新的核心人员，现有核心员工的新项目资金以及核心人员与外部调查人员之间的新合作努力。 With a projected increase in animal numbers, a need to upgrade cage wash facilities, and a need to expand surgical capabilities for upcoming projects, the University of Washington has committed $5.6 million to expand the vivarium by approximately 2500 square feet at the WaNPRC Western facility, install a new cage-wash/autoclave facility and build a state-of-the-art surgical suite for the support of AIDS-related research.我们要求额外的资金将当前的手术区域转换为动物外壳，并在扩大的动物饲养空间内建立其他区域。拟议的动物持有室将容纳80组四（10-15公斤）非人类灵长类动物或更多较小的动物。这些房间将根据《实验动物的护理和使用指南》第八版的建议来建造。动物持有空间的完成将协同补充由机构资助的项目升级笼子清洗设施和外科套件，并将改善并提高我们进行生物医学研究的能力，尤其是与艾滋病相关的研究。