VISUAL PROCESSING AND SMOOTH EYE MOVEMENTS

视觉处理和平滑的眼球运动

• 批准号: 8357613
• 负责人: Michael J Mustari
• 金额: $ 15.66万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357613
• 关键词: Brain Stem; Development; Diagnosis; Eye; Eye Movements; Funding; Goals; Grant; Lead; Macaca; Modeling; National Center for Research Resources; Neurons; Ocular Motility Disorders; Pathologic Nystagmus; Primates; Principal Investigator; Research; Research Infrastructure; Research Project Grants; Resources; Role; Smooth Pursuit; Source; Strabismus; United States National Institutes of Health; Visual; cell motility; cost; experience; gaze; improved; infancy; insight; relating to nervous system; visual process; visual processing

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The purpose of this research project is to consider the role of early visual experience in development of gaze-holding, eye alignment and ocular motility (smooth pursuit). Special emphasis is devoted to cortical and associated brainstem neurons essential for gaze-holding and eye movements of strabismic macaques. The goal is to determine the neural substrate responsible for eye movement disorders such as latent nystagmus, asymmetric smooth pursuit and strabismus associated with impoverished binocular visual experience. We have developed effective macaque models for strabismus, which provide insight into neural correlates related to infantile strabismus that could lead to improved diagnosis and treatments.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 该研究项目的目的是考虑早期视觉体验在凝视，眼睛对准和眼动运动（平稳追捕）中的作用。特别的重点是对斜视猕猴的注视和眼动运动至关重要的皮质和相关的脑干神经元。目的是确定负责眼运动障碍的神经底物，例如潜在的眼球震颤，不对称的平滑追击和与贫困双眼视觉体验相关的斜视。我们已经开发了有效的斜视模型，这些模型可以洞悉与婴儿斜视相关的神经相关性，这可能会导致诊断和治疗的改善。