The short and long-term dynamics of opioid/stimulant use: Mixed methods to informoverdose prevention and treatment related to polysubstance use

阿片类药物/兴奋剂使用的短期和长期动态：与多物质使用相关的过量预防和治疗的混合方法

• 批准号: 10841942
• 负责人: DANIELLE GERMAN
• 金额: $ 16.27万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-30 至 2024-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10841942
• 关键词: Administrative Supplement; Baltimore; Collection; Communities; Complement; Data; Data Collection; Drug Interactions; Drug user; Ecological momentary assessment; Elements; Employment Status; German population; Goals; Imprisonment; Individual; Intervention; Interview; Knowledge; Legal; Legal system; Link; Long-Term Effects; Measures; Mediating; Methods; Opioid; Parents; Pathway interactions; Perception; Persons; Police; Police officer; Prevention; Recovery Support; Research Personnel; Role; Services; Substance Use Disorder; Time; cohort; effectiveness trial; experience; housing instability; parent project; polysubstance use; recovery services; recruit; response; skills; social determinants; stimulant use; substance use; treatment services

Project summary In response to NOT-DA-23-011, this administrative supplement will expand the scope of the parent project (R01DA057673, MPI: Genberg and German) on short and long-term effects of polysubstance use to incorporate collection of quantitative and qualitative data on criminal legal involvement. Specifically, this application will broaden and complement the skills of our investigative team to include researchers with expertise on characterizing the intersection of substance use and criminal legal involvement, with a focus on people who use drugs’ interaction with street-level police officers. The overall objective of this administrative supplement is to elucidate the relationship between polysubstance use and encounters with police and other elements of the criminal legal system in a community-recruited cohort of people who use drugs in Baltimore, MD. To date, most studies have only examined the association between polysubstance use and incarceration cross-sectionally, yet rigorous longitudinal data on the upstream drivers of incarceration, such as interactions with police, are lacking. Overcoming this knowledge gap is important as pre-arrest diversion is seen as a critical opportunity for police to link people who use drugs to community-based recovery services yet our understanding on police-PWUD interactions is limited with respect to polysubstance use. Thus, we intend to collect detailed quantitative and qualitative data on anticipated and realized experiences with street-level police (e.g. stopped, arrested, harassed) among PWUD by accomplishing the following specific aims to: 1) evaluate real-time associations between polysubstance use and the mediating role of social determinants (e.g. housing instability and employment status) on negative police encounters; and 2) characterize experiences, perceptions, and consequences of criminal legal involvement during polysubstance using episodes. We will accomplish Aim 1 by adding criminal legal involvement measures to ongoing data collection of ecological momentary assessments among 200 PWUD. To complement the quantitative results, we will conduct 20 in- depth interviews with PWUD who had recent encounters with street-level police to contextualize the findings in Aim 1. We will leverage findings from this supplement to inform an R34 preliminary effectiveness trial to pilot pre-arrest deflection to recovery support, MOUD, and wrap-around services for people with severe substance use disorder, including individuals who engage in polysubstance use.

项目概要 为了响应 NOT-DA-23-011，本行政补充文件将扩大父项目的范围 （R01DA057673，MPI：Genberg 和 German）关于多物质使用的短期和长期影响 具体来说，这 应用程序将扩大和补充我们研究团队的技能，包括具有以下能力的研究人员 表征药物使用和刑事法律参与交叉的专业知识，重点是 吸毒者与街头警察的互动 本次行政管理的总体目标。 补充是为了阐明多物质使用与遭遇警察和其他人之间的关系 在巴尔的摩社区招募的一批吸毒者中了解刑事法律制度的要素， 迄今为止，大多数研究仅研究了多种物质使用与监禁之间的关联。 关于监禁上游驱动因素的横断面但严格的纵向数据，例如相互作用 克服这种知识差距很重要，因为逮捕前转移被视为一种手段。 警察有机会将吸毒者与基于社区的康复服务联系起来，但我们 对警察与残疾人士和警察局之间互动的了解在多物质使用方面是有限的，因此，我们打算这样做。 收集有关街头警察预期和实际经验的详细定量和定性数据 通过实现以下具体目标，在 PWUD 中进行拦截（例如拦截、逮捕、骚扰）：1) 评估 多物质使用与社会决定因素（例如住房）的中介作用之间的实时关联 不稳定和就业状况）关于与警察的负面接触；以及 2）描述经历， 我们将在多物质使用事件中对刑事法律卷入的看法和后果。 通过在持续的生态数据收集中增加刑事法律介入措施来实现目标 1 为了补充定量结果，我们将在 200 名残疾人中进行临时评估。 对最近与街头警察接触过的 PWUD 进行深度访谈，以将调查结果结合起来 目标 1. 我们将利用本补充材料的研究结果为 R34 初步有效性试验提供信息 逮捕前转向康复支持、MOUD 以及为患有严重物质问题的人提供全方位服务 使用障碍，包括使用多种物质的个人。