Arsenicals in infant foods

婴儿食品中的砷

• 批准号: 10819973
• 负责人: Jeremy Davidson Bailoo
• 金额: $ 1.72万
• 依托单位: TEXAS TECH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-06 至 2025-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10819973
• 关键词: Address; American; Animal Model; Arsenic; Arsenicals; Biological Markers; Cacodylic Acid; Childhood; Consumption; Critical Thinking; Degree program; Development; Developmental Biology; Diet; Enrollment; Evaluation; Exposure to; Female; Generations; Health; Infant Food; Knowledge; Learning; Malaysian; Medical; Metabolism; Microbiology; National Institute of Environmental Health Sciences; Nerve Degeneration; Outcome; Pathologic; Publishing; Research; Students; Supervision; Texas; Toxic Environmental Substances; Training Programs; Universities; Work; Writing; environmental chemistry; environmental toxicology; in vivo; parent grant; parent project; programs; recruit; skills; symposium

PROJECT SUMMARY The purpose of this supplement (PA-21-071) is to “enhance the diversity of the research workforce by recruiting and supporting students….including those from groups that have been shown to be underrepresented in health- related research”. Aarthi Annamalai will be a trainee on the on-going NIEHS project (R03ES034194:”Evaluation of the timing and duration of low level dimethylarsinic acid exposure to its fate, metabolism, and development of neurodevelopmental and neurodegenerative biomarkers). Ms. Annamalai is a female, first generation Malaysian-American student, currently enrolled in the Microbiology program at Texas Tech University. Ms. Annamalai will graduate in Spring 2024 and aims to start her medical degree program after graduating with her BS. In the proposed research plan, which is a reasonable extension of the parent project, Ms. Annamalai will evaluate total arsenic and arsenic species prevalent in infant foods under the supervision of Drs. Amrika Deonarine and Jeremy Bailoo (PIs of the parent grant). The project will extend the scope of the parent grant from an in vivo animal model to a comprehensive evaluation of arsenic speciation of commonly consumed infant foods identified in the FDA’s Total Diet Study. Ms. Annamalai will utilize her knowledge of developmental biology and environmental chemistry to solve real problems in environmental toxicology in relation to pathological outcomes in childhood. Ms. Annamalai will have the opportunity to present her work at a national conference and will learn how to write and publish a research article. Through this project, Ms. Annamali will learn critical thinking, develop experimental skills, and conduct independent research. The entire training program will provide a platform for her to address contemporary medical issues as a consequence of exposure to environmental toxins, such as arsenic.

项目概要 本补充文件 (PA-21-071) 的目的是“通过招募研究人员来增强研究人员的多样性” 并支持学生……包括来自在健康方面代表性不足的群体的学生- Aarthi Annamalai 将成为正在进行的 NIEHS 项目的实习生（R03ES034194：“评估”） 低浓度二甲基胂酸暴露的时间和持续时间对其命运、代谢和发育的影响 Annamalai 女士是女性，第一代 马来西亚裔美国学生，目前就读于德克萨斯理工大学微生物学课程。 Annamalai 将于 2024 年春季毕业，目标是在毕业后与她一起开始医学学位课程 BS。在拟议的研究计划中，这是母项目的合理延伸，Annamalai 女士将 在 Amrika 博士的监督下评估婴儿食品中普遍存在的总砷和砷形态。 Deonarine 和 Jeremy Bailoo（母基金的 PI） 该项目将扩大母基金的范围。 综合评价常用婴儿食品中砷形态的体内动物模型 FDA 的总体饮食研究中确定，Annamalai 女士将利用她的发育生物学知识和 环境化学解决环境毒理学中与病理结果相关的实际问题 Annamalai 女士在童年时将有机会在全国会议上展示她的作品并学习。 如何撰写和发表研究文章 通过这个项目，Annamali 女士将学习批判性思维，发展。 整个培训计划将为学生提供实验技能，并进行独立研究的平台。 她致力于解决因暴露于环境毒素而导致的当代医学问题，例如 砷。