UK NETT Clinical Site Hub

英国 NTT 临床站点中心

基本信息

批准号：
7837572
负责人：
Roger Loyd Humphries
金额：
$ 19.41万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-05-03 至 2012-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7837572
关键词：
Academic Medical Centers Accident and Emergency department Acute Adult Advanced Cardiac Life Support Agreement Air Ambulances American College of Surgeons Brain Caring Cities Clinical Trials Collaborations Communication Community Hospitals Consent County Disease model Doctor of Medicine Emergency Medicine Emergency Situation Emergency medical service Emergency treatment Enrollment Environment Evaluation Faculty Fire - disasters Goals Government Head Hospitals Internet Investigational Therapies Kentucky Medical Medical Faculty Medical center Medicine Neurological emergencies Neurology Operative Surgical Procedures Patient Recruitments Patients Physicians Positioning Attribute Principal Investigator Provider Randomized Rehabilitation therapy Research Research Infrastructure Research Personnel Resources Rural Rural Population Services Speed Spinal Cord Spinal cord injury Trauma Universities University Hospitals Urban Hospitals Veterans base clinical research site college design experience meetings member nervous system disorder neurosurgery professor response trauma centers treatment trial

项目摘要

DESCRIPTION (provided by applicant): This proposal describes the establishment of a Neurological Emergencies Treatment Trials (NETT) Network Clinical Site Hub at the University of Kentucky Medical Center (UKMC) in Lexington, Kentucky, in response to NIH/NINDS RFA-NS-06-009. The overall goal of this proposal is to identify UKMC as an academic medical facility with regional affiliate partners adept in "the evaluation of treatments for patients with a broad spectrum of neurological emergencies." The NETT Clinical Site Hub at UKMC is founded upon an intra- institutional collaboration between physician faculty members of the Departments of Emergency Medicine, Neurology, and Neurosurgery. Regional affiliate medical care facilities aligned with UKMC include the Department of Veterans Affairs Medical Center/Cooper Drive Division (DVAMC/CDD) in Lexington and "spoke" community hospitals located in non-urban environments throughout Central and Eastern Kentucky. The following Specific Aims are proposed: 1) To demonstrate the existence of an infrastructure for patient recruitment in "large, simple" clinical trials performed in acute-onset neurological disorders modeled by TBI, drawing upon the resources of a Level 1 Trauma Center situated within a broadly-based geographical network of referring hospitals in non-urban settings and 2) To demonstrate the existence of an infrastructure for patient recruitment in clinical trials performed in acute-onset neurological disorders, requiring Exception to Consent for Emergency Research.

描述（由申请人提供）：该提案描述了在肯塔基州列克星敦的肯塔基大学医学中心 (UKMC) 建立神经急症治疗试验 (NETT) 网络临床中心中心，以响应 NIH/NINDS RFA-NS- 06-009。该提案的总体目标是将 UKMC 确定为学术医疗机构，其区域附属合作伙伴擅长“对患有广泛神经系统紧急情况的患者进行治疗评估”。 UKMC 的 NETT 临床站点中心是在急诊医学、神经病学和神经外科部门的医师教员之间的机构内合作基础上建立的。与 UKMC 合作的地区附属医疗机构包括位于列克星敦的退伍军人事务部医疗中心/库珀大道分部 (DVAMC/CDD) 以及位于肯塔基州中部和东部非城市环境中的“辐射”社区医院。提出以下具体目标： 1) 利用位于 TBI 的 1 级创伤中心的资源，证明在以 TBI 为模型的急性发作神经系统疾病中进行的“大型、简单”临床试验中招募患者的基础设施的存在非城市地区转诊医院的广泛地理网络，以及 2) 证明在急性发作神经系统疾病临床试验中存在招募患者的基础设施，需要紧急研究同意例外。