Clinical effectiveness of a wearable hydration device

可穿戴水化装置的临床效果

• 批准号: 10773374
• 负责人: Eamon Johnson
• 金额: $ 5.46万
• 依托单位: TRITONX INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10773374
• 关键词: Academic Medical Centers; Accident and Emergency department; Acute; Aftercare; Area; Body Water; Businesses; Chronic Disease; Clinical; Clinical effectiveness; Communication; Computer software; Dehydration; Development; Devices; Diabetes Mellitus; Disease; Elderly; Emergency Care; Environment; Evaluation; Funding; Future; Grant; Health; Healthcare; Healthcare Systems; Heart Diseases; Home; Hydration status; Individual; Industry; Innovation Corps; Institutional Review Boards; Kidney Diseases; Laboratories; Lead; Learning; Life; Light; Liquid substance; Marketing; Measures; Medical; Migraine; Monitor; Persons; Phase; Process; Protocols documentation; Quality of life; Research; Resources; Sales; Small Business Technology Transfer Research; Techniques; Technology; Time; Training; Water; Work; commercialization; design; experience; extracellular; improved; innovation; member; programs; prototype; success; ward

Executive Summary of Predicate STTR Phase 1 Grant and Team This application seeks supplemental funding for growing our business around an innovative approach to measuring hydration. Our company is seeking STTR funding to refine our technique and demonstrate its utility in an area of high clinical need, in partnership with an academic medical center. At TritonX we believe that the future of health & wellness is in continuous monitoring. Monitoring hydration is a daily challenge for millions of people, especially older adults and people with common chronic diseases - migraines, kidney disease, heart disease, diabetes and other serious conditions. We have developed a wearable continuous hydration monitor that can detect users’ total body water, intracellular and extracellular water in real time to help them lead a better life, ward off diseases and maintain or improve their quality of life. Our company seeks to eliminate the burdens caused by dehydration not only on individuals but also on the health care system. Progress toward aims of our Phase I aims: Aim 1: Determine the ideal user experience, device settings and health care communication needs when conducting continuous monitoring of fluid levels among older adults in their homes. Progress: We have redesigned our prior prototype device, removing unnecessary features and upgrading components to increase efficiency and reliability for the current study. The improved device will enable us to better focus on customer experience as opposed to technical support. Aim 2: Compare device measured fluid levels to clinical and laboratory parameters pre and post treatment among acutely ill older adults presenting to the emergency department for dehydration. Progress: We have established protocols and identified team members to conduct our study in the proposed emergency care environment. IRB approval is complete. We have trained staff on protocols using our device. I-Corps Team Our I-Corps team: ? Corporate Officer: Dr Éamon Johnson, CEO TritonX Inc ? Technical Lead: Shravan Khare, CTO TritonX Inc ? Industry Expert: Greg Davis, advisor to TritonX Inc Dr Johnson and Mr Khare are founders of TritonX Inc and have devoted substantial personal resources to development of the small business and the technology. Mr Khare is the inventor of the technology. Mr Davis is an investor and advisor with TritonX with 25 years of experience in medical software sales and marketing. Dr Johnson and Mr Davis have worked closely for six years in research commercialization in health software. The team is committed to the success of the company and ready to commit to the I-Corps program fully. We view the program as an essential learning opportunity and look forward with great anticipation to the process of customer discovery. We are committed to thorough re-evaluation of our value proposition in light of the market reality we will discover through the I-Corps process.

Predicate STTR 第一阶段拨款和团队的执行摘要 该申请寻求补充资金，以围绕创新方法发展我们的业务 我们公司正在寻求 STTR 资金来改进我们的技术和 与学术医疗中心合作，展示其在高临床需求领域的实用性。 在 TritonX，我们相信健康与保健的未来在于持续监控。 补水是数百万人每天面临的挑战，尤其是老年人和患有常见病的人 慢性疾病 - 偏头痛、肾病、心脏病、糖尿病和其他严重疾病。 开发了一种可穿戴式连续水合监测器，可以检测用户的体内总水分， 实时监测细胞内和细胞外水，帮助他们过上更好的生活，预防疾病和 我们公司力求消除他们造成的负担。 脱水不仅影响个人，也影响医疗保健系统。 我们第一阶段目标的进展： 目标 1：确定理想的用户体验、设备设置和医疗保健通信需求 对家中老年人的液体水平进行连续监测时。 进展：我们重新设计了之前的原型设备，删除了不必要的功能并 升级组件以提高当前研究的改进设备的效率和可靠性。 将使我们能够更好地关注客户体验而不是技术支持。 目标 2：将设备测量的液位与前后的临床和实验室参数进行比较 对因脱水而到急诊科就诊的急症老年人进行治疗。 进展：我们已经制定了方案并确定了团队成员来进行我们的研究 拟议的紧急护理环境已完成IRB 批准。我们已对工作人员进行了协议培训。 使用我们的设备。 I军团团队 我们的 I-Corps 团队： 公司官员：TritonX 公司首席执行官 Éamon Johnson 博士 技术主管：Shravan Khare，TritonX Inc 首席技术官 行业专家：Greg Davis，TritonX Inc 顾问 Johnson 博士和 Khare 先生是 TritonX Inc 的创始人，并投入了大量的个人资源 哈雷先生是小企业和技术的发明者。 TritonX 的投资者和顾问，拥有 25 年医疗软件销售和营销经验。 约翰逊和戴维斯先生在健康软件研究商业化方面密切合作了六年。 该团队致力于公司的成功，并准备充分致力于 I-Corps 计划。 将该计划视为一次重要的学习机会，并满怀期待地期待这一过程 我们致力于根据市场彻底重新评估我们的价值主张。 我们将通过 I-Corps 流程发现现实。