Multiscale Biophotonics: A Platform for Interdisciplinary Biomedical Research Training and Career Development

多尺度生物光子学：跨学科生物医学研究培训和职业发展的平台

• 批准号: 10703493
• 负责人: BERNARD CHOI
• 金额: $ 42.41万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-12 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703493
• 关键词: Academia; Active Learning; Address; Applications Grants; Area; Articulation; Automobile Driving; Biological Sciences; Biomedical Research; Biomedical Technology; Biophotonics; Biophysics; Biotechnology; California; Career Choice; Case Study; Code; Color; Comprehension; Computer Analysis; Computer software; Custom; Development; Development Plans; Engineering; Faculty; Feedback; Fellowship; Fostering; Foundations; Frequencies; Geographic Locations; Goals; Growth; Image; Individual; Industrialization; Industry; Journals; Laboratories; Leadership; Learning; Learning Module; Measurement; Measures; Medical Device; Mentors; Mentorship; Microscopy; Modeling; Monitor; National Institute of General Medical Sciences; Performance; Phototherapy; Postdoctoral Fellow; Problem-Based Learning; Procedures; Publications; Questionnaires; Research; Research Personnel; Research Training; Schedule; Science; Scientist; Site; Students; Surveys; Technology; Thinking; Time; Tissues; Training; United States National Institutes of Health; Universities; Workforce Development; biomedical scientist; career; career development; course module; data acquisition; design; early-career faculty; economic impact; evidence base; experience; experimental study; faculty research; graduate student; innovation; instrument; instrumentation; laboratory module; learning outcome; lectures; meetings; metacognition; multidisciplinary; open source; outreach; point-of-care diagnostics; programs; project-based learning; research and development; simulation software; skill acquisition; skills; symposium; technology development; tool; virtual

PROJECT SUMMARY The overarching objectives and specific aims of this IPERT program are to (1) prepare trainees for successful multi-disciplinary Biophotonics careers and support biomedical workforce development. This will be achieved by (2) advancing the technical and operational proficiency of our trainees in Multiscale Biophotonics through an integration of modeling, computation, experiment, and problem-based learning, and (3) providing our trainees with sustained mentorship for professional development. This will be accomplished by establishing foundational technical and operational skills in the area of Multiscale Biophotonics during a 12-day onsite short course at the University of California, Irvine. This 12-day short course utilizes an integrated modular design and evidence based learning consisting of (a) lectures, (b) technology demonstrations, (c) laboratories combining hands-on data acquisition with computational analysis using our custom Virtual Tissue Simulator (VTS) software platform, (d) Team Science training, (e) mentored capstone problem-based learning (PBL) proposal development, (f) guest lectures on the use of an interdisciplinary Biophotonics approach to address biomedical problems, (g) panel discussions on academic and industrial career paths, and (h) tours of academic and industrial facilities. Further application and growth in trainee skill development will be accomplished by a mentored capstone problem-based learning project to be pursued for one year following the short course completion. In parallel with the short course and year-long PBL project, we will offer both technical and professional mentorship. Our technical mentorship aims to support Biophotonics, instrument and measurement design, technology development, as well as modeling, computation and usage of open-source Computational Biophotonics Tools. Our professional mentorship program aims to aid trainees in identifying appropriate short- and long-term professional goals and develop strategies to attain them. The course has been designed for interdisciplinary group of graduate student, post- doctoral researcher, and faculty scientists and engineers. We propose an aggressive outreach plan to support the participation of trainees who are traditionally underrepresented within STEM as well as from geographic regions that have historically received low levels of NIH support. We aim to train up to 20 individuals each year. In summary, our program provides a technical foundation and mentoring support for trainees to advance and apply an integrated technical proficiency in Multiscale Biophotonics to solve biomedical challenges. As the integration of expertise spanning modeling, computation and experiment are in demand in biomedical research and technology development, the proposed program advances NIGMS programmatic goals for training a diverse biomedical research workforce with expertise most relevant to the NIGMS Division of Biophysics, Biomedical Technology, and Computational Biosciences.

项目概要 该 IPERT 计划的总体目标和具体目标是 (1) 为学员​​做好准备 成功的多学科生物光子学职业并支持生物医学劳动力发展。这将 通过 (2) 提高多尺度学员的技术和操作熟练程度来实现 通过集成建模、计算、实验和基于问题的学习来实现生物光子学，以及 (3) 为学员​​提供持续的专业发展指导。这将实现 通过在多尺度生物光子学领域建立基础技术和操作技能 加州大学欧文分校为期 12 天的现场短期课程。这个为期 12 天的短期课程利用 集成模块化设计和基于证据的学习，包括 (a) 讲座、(b) 技术 演示，(c) 实验室将动手数据采集与使用我们的计算分析相结合 定制虚拟组织模拟器 (VTS) 软件平台，(d) 团队科学培训，(e) 指导顶峰 基于问题的学习（PBL）提案制定，（f）关于使用跨学科方法的客座讲座 解决生物医学问题的生物光子学方法，(g) 学术和工业小组讨论 职业道路，以及 (h) 参观学术和工业设施。受训者技能的进一步应用和增长 发展将通过一个有指导的基于问题的学习项目来完成 短期课程完成后一年。在短期课程和为期一年的 PBL 项目的同时， 我们将提供技术和专业指导。我们的技术指导旨在支持 生物光子学、仪器和测量设计、技术开发以及建模、 开源计算生物光子学工具的计算和使用。我们的专业指导 该计划旨在帮助学员确定适当的短期和长期职业目标并制定 实现这些目标的策略。该课程是为跨学科的研究生群体设计的， 博士研究员、教师科学家和工程师。我们提出了一项积极的外展计划来支持 传统上 STEM 以及来自不同地区的学员的参与 历史上获得 NIH 支持水平较低的地区。我们的目标是每人培训最多 20 人 年。 总之，我们的计划为学员的进步提供了技术基础和指导支持 并应用多尺度生物光子学的综合技术能力来解决生物医学挑战。作为 生物医学需要建模、计算和实验等专业知识的整合 研究和技术开发，拟议的计划推进了 NIGMS 的计划目标 培训具有与 NIGMS 部门最相关专业知识的多元化生物医学研究人员 生物物理学、生物医学技术和计算生物科学。