Medical Scientist National Research Service Award

医学科学家国家研究服务奖

• 批准号: 10703834
• 负责人: Marcus Ramsay Clark
• 金额: $ 127.72万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10703834
• 关键词: Medical; National Research Service Awards; Scientist

PROJECT SUMMARY The mission of The University of Chicago (UChicago) Medical Scientist Training Program (MSTP) is to train the next generation of clinician-scientists for impactful careers in the biomedical sciences. Impact is broadly defined as: providing fundamental insights into disease and relevant biological mechanisms, leading or making substantial contributions to translational efforts to identify better therapies and/or filling leadership roles that will determine how limited resources can best be used to improve human health. Our overall objective is to train outstanding and self-directed clinician scientists who can formulate and answer biologically and medically- important questions. To ensure the greatest impact, our program must reflect the diversity of the U.S. population in both who it trains and who it serves. To accomplish our mission and overall objective, we defined 15 specific and measurable objectives that stress the technical, operational and professional skills that support science identity and self-efficacy and are critical for a successful career as an independent biomedical investigator. Two unique features of the program enable our mission and provide an optimal training environment for the development of clinician-scientists. First, we are our own graduate program, the Interdisciplinary Scientist Training Program (ISTP). The ISTP allows integration of graduate and medical school classes in MS1, development of tailored curricula for each trainee, coordination across training transitions and uniform oversight and expectations during the graduate phase. Second, most trainees pursue a 1-4-3 progression of study rather than the traditional 2-4-2 progression. While trainees may pursue a 2-4-2, the 1-4-3 provides a continuous and in-depth graduate experience where trainees become well-trained scientists who can propose and rigorously test hypotheses. The 1-4-3 also provides a seamless transition between the preclinical and clinical phases which facilitates overall success in medical school. Multiple programmatic features ensure that fundamental scientific and clinical knowledge are interwoven to foster the development of impactful clinician-scientists. The UChicago MSTP enjoys sustained and substantial University financial backing including generous direct investment and support of facilities that cultivate innovative science. We are requesting 25 training slots to supplement University investments to support trainees for six of the typical eight years they spend in the MSTP. This requested investment by the NIH would constitute only 13% of total anticipated cost for our MSTP. We anticipate a program size of approximately 80 trainees and expect, based on our track record, that our trainees will contribute significantly to the U.S. biomedical enterprise.

项目概要 芝加哥大学 (UChicago) 医学科学家培训计划 (MSTP) 的使命是培训 下一代临床医生科学家在生物医学领域从事有影响力的职业。影响广泛 定义为：提供对疾病和相关生物机制的基本见解，领导或制造 为转化努力做出重大贡献，以确定更好的疗法和/或填补领导角色，这将 确定如何最好地利用有限的资源来改善人类健康。我们的总体目标是训练 杰出且自我指导的临床科学家，他们可以从生物学和医学角度制定和回答- 重要的问题。为了确保产生最大的影响，我们的计划必须反映美国的多样性。 其培训对象和服务对象的人口。为了完成我们的使命和总体目标，我们定义 15 个具体且可衡量的目标，强调支持的技术、操作和专业技能 科学认同和自我效能对于独立生物医学工作者的成功职业生涯至关重要 研究者。该计划的两个独特功能使我们能够完成使命并提供最佳的培训 为临床医生科学家的发展提供环境。首先，我们是我们自己的研究生项目， 跨学科科学家培训计划（ISTP）。 ISTP 允许研究生和医学专业的融合 MS1 中的学校课程、为每位学员开发定制课程、跨培训协调 研究生阶段的过渡以及统一的监督和期望。其次，大多数学员追求的是 1-4-3 学习进度而不是传统的 2-4-2 进度。虽然受训者可能会追求 2-4-2 阵型， 1-4-3 提供持续、深入的研究生体验，让学员成为训练有素的科学家 谁可以提出并严格检验假设。 1-4-3 还提供了之间的无缝过渡 临床前和临床阶段，促进医学院的整体成功。多程序化 特点确保基础科学和临床知识相互交织，以促进发展 有影响力的临床医生科学家。芝加哥大学 MSTP 享有持续且可观的大学财政支持 支持包括慷慨的直接投资和对培育创新科学设施的支持。我们是 请求 25 个培训名额来补充大学投资，以支持典型 8 个培训中的 6 个培训名额 他们在 MSTP 中度过了数年。 NIH 请求的投资仅占总投资的 13% 我们的 MSTP 的预期成本。我们预计该计划规模约为 80 名受训人员，并期望基于 根据我们的记录，我们的学员将为美国生物医学事业做出重大贡献。